Postgraduate research

Health Sciences

Allied Health Professions

Professor Debi Bhattacharya

My research programmes focus on applying behavioural science to medicines optimisation challenges and intervention implementation. Recent studies include:

  • Developing and validating scales to identify the determinants and magnitude of medication adherence for people prescribed multiple medicines

  • Developing deprescribing interventions for dependence forming medication and polypharmacy in older people

  • Developing a theory and evidence informed framework of dissemination


Professor David Wright

  • Medicines optimisation for older people in care homes
  • Medicines administration for people with dysphagia
  • Integration of community pharmacy services within primary care

Dr Sion Scott

  • Application of behavioural science to design and evaluate interventions targeting practitioner and patient behaviour
  • Deprescribing for older people in the hospital setting
  • Addressing barriers to medication adherence

 

Biostatistics

Dr Rebecca Baggaley

  • Infectious Disease Epidemiology
  • Infection Transmission Mathematical Modelling
  • Economic Evaluations, in particular Decision Analytic and Markov Modelling
  • Measuring Wider Impacts of COVID-19 Interventions
  • Infectious Disease Screening Strategies for Hard-to-Reach Populations

Dr Sarah Booth

  • Survival analysis and competing risks
  • Methodology for developing, validating and updating prognostic models
  • Analysis of population-based cancer registry data

Professor Sylwia Bujkiewicz

  • Methods for Multi-parameter Evidence Synthesis
  • Bayesian Methods in Healthcare Evaluation
  • Bayesian Evidence Synthesis for Surrogate Endpoints Evaluation
  • Statistical Methods in Health Technology Assessment

Professor Nicola Cooper

  • Interface and Integration of Medical Statistics and Health Economics
  • Methods for Statistical Modelling of Cost Data
  • Integration of Evidence Synthesis within a Decision-Modelling Context
  • Handling of Missing Data in Economic Evaluations Conducted Alongside Clinical Trials
  • Application of Bayesian Statistical Methods to the above 

Dr Suzanne Freeman

  • Multi-parameter Evidence Synthesis includng Network Meta-Analysis and Component Network Meta-Analysis
  • Evidence Synthesis of Time-To-Event Outcomes
  • Individual Participant Data Meta-Analysis and Network Meta-Analysis
  • Bayesian Evidence Synthesis

Professor Laura Gray

  • Design and Analysis of Clinical Trials (particularly cluster and stepped wedge trials and those testing complex interventions)
  • Systematic Reviews and Meta-Analysis
  • Prognostic Model Development and Validation

Dr Stephanie Hubbard

  • Statistical Methods for Systematic Reviews and Meta-analysis
  • Meta-Analysis and Network Meta-Analysis of Complex Multi-Component Interventions
  • Evidence Synthesis of Public Health Interventions

Professor Paul Lambert

  • Relative Survival Methods, in particular Modelling of Excess Mortality
  • Casual Inference Methods
  • Epidemiological Design

Dr Tim Lucas

  • Environmental epidemiology
  • Machine learning
  • Global health
  • Spatial statistics

Dr Mark Rutherford

  • Methods for Analysing Population-Based Registry Data
  • Relative Survival Methods and Competing Risks Methodology
  • Modelling and Projecting Cancer Incidence
  • Prognostic Model Development and Validation
  • Approaches for Extrapolating Survival Curves

Professor Alex Sutton

  • Meta-Analysis and Systematic Review Methods
  • Multi-Parameter Evidence Synthesis Including Network Meta-Analysis
  • Statistical Methods in Health Economics and Health Technology Assessment
  • Graphical Methods For Displaying Statistical Information 

Dr Lucy Teece

  • Health inequalities and improving research generalisability
  • COVID-19 and long-COVID related research
  • Prognosis research including prognostic model development and validation
  • Survival analysis methods including competing risks

Diabetes Research Centre

Dr Ffion Curtis

  • Lifestyle interventions in community and clinical settings
  • Prevention and management of chronic conditions such as diabetes and multimorbidity
  • Systematic reviews of quantitative and qualitative studies

Professor Melanie Davies, CBE

  • Lifestyle and obesity management for diabetes prevention and management
  • Management of diabetes and cardiovascular risk in South Asian populations
  • Clinical trial design
  • Lifestyle and physical activity interventions in the treatment of chronic disease
  • Clinical trial design
  • Complex interventions, including self-management and diabetes prevention
  • Novel glucose lowering therapies
  • Sedentary behaviour and health
  • Novel therapies for obesity
  • Type 2 diabetes mellitus in younger patients
  • Diabetes screening
  • Type 2 Diabetes

Dr Charlotte Edwardson

  • Levels and patterns of physical activity and sedentary behaviour in different populations
  • Effects of physical activity and sedentary behaviour on metabolic health and chronic disease
  • Interventions to increase physical activity and reduce sedentary behaviour
  • Objectively measured physical activity and sedentary behaviour
  • Randomised controlled trials

Dr Clare Gillies

  • Use of real world data for health research
  • Evidence synthesis and decision models for health research
  • Systematic Reviews and Meta-Analysis
  • Prevention of diabetes and cardiovascular disease 

Dr Pankaj Gupta

  • Non -Adherence to medications: Its diagnosis and management using novel chemical adherence testing by LC-MS/MS
  • Study of Renin angiotensin aldosterone axis and its counter regulation
  • Resistant Hypertension:  Causes and Management
  • Biofeedback to manage patients with multiple medication intolerances

Dr Michelle Hadjiconstantinou

  • Behaviour change
  • Qualitative research methods (exploratory, evaluation)
  • Theory-based intervention development (including behavioural lifestyle self-management interventions, diabetes prevention)
  • Digital-based interventions
  • Long-term conditions and Multi-morbidity (i.e. type 2 diabetes, type 1 diabetes)
  • Patient-reported outcome measures

Professor Kamlesh Khunti

  • Epidemiological studies of diabetes and cardiovascular disease and early detection and screening for these diseases, in particular among South Asian people
  • Interventional studies of prevention and management of people with of type 2 diabetes and cardiovascular disease
  • Models of delivering care for people with diabetes and cardiovascular disease
  • Hypoglycaemia
  • Therapeutic inertia
  • Multimorbidity
  • Covid-19 related research

Dr Samuel Seidu

  • Systematic Reviews and Meta-Analysis
  • Management of older people with diabetes and cardiometabolic multimorbidity 
  • Epidemiological studies of diabetes and cardiovascular disease  
  • Interventional studies of prevention of type 2 diabetes and cardiovascular disease 
  • Models of delivering care for people with diabetes and cardiovascular disease 
  • Therapeutic inertia 

Dr Alex Rowlands

  • Accelerometer measurement of free-living physical behaviours (physical activity, sedentary behaviour and sleep)
  • Analytical methods for the quantification of physical behaviours
  • Effects of physical behaviours on health

Dr David Webb

  • Continous Glucose Monitoring and hyperinsulinaemic – euglycaemic clamp systems
  • Novel biomarkers in the prediction and management of Type 2 diabetes
  • Insulin sensitivity measures and their therapeutic application in human diabetes research
  • Epidemiology of screen-detected type 2 diabetes and early phase glucose dysregulation
  • Novel vasculopathic mechanisms in Type 1 and Type 2 Diabetes mellitus

Dr Thomas Wilkinson

  • Applied health research 
  • Lifestyle (including dietary, exercise, and physical activity) interventions in the treatment of chronic disease, in particular chronic kidney disease and those living with multimorbidity 
  • Sarcopenia and frailty in those living with chronic diseases
  • Evaluation of clinimetric properties of patient reported outcome measures (PROMs)

Dr Thomas Yates

  • Effects of sedentary behaviour and different types of physical activity on metabolic health
  • Treatment and prevention of type 2 diabetes and chronic disease by decreasing sedentary behaviour, and increasing light movement, walking or more intensive movement-based therapies
  • Interaction between mediation and lifestyle therapies (diet and exercise) for weight loss and diabetes management
  • Physical activity and obesity epidemiology using regional, national and international datasets
  • Translating physical activity and diabetes prevention programmes into routine practice

Dr Francesco Zaccardi

  • Use of large electronic health record datasets for epidemiological investigations  
  • Statistical models for etiological, demographic, and prognostic research
  • Use of alternative risk metrics for clinical interpretation of RCTs
  • Comparative-effectiveness pharmacoepidemiological studies
  • Evidence-based medicine and clinical guidelines

Genetic Epidemiology

Professor Frank Dudbridge

  • Statistical Methods in Genetic Association Studies
  • Prediction of Disease Risk from Genetic Data
  • Mendelian Randomisation for Causal Inference in Epidemiology
  • Integrative Analysis of Genetic, Epigenetic and –Omic Data
  • Evolutionary Analysis of Malignant Tumour
  • Genetic Epidemiology of Cardiovascular Disease, Breast Cancer, and Psychiatric Disorders

Dr Anna Guyatt

  • Epidemiology of multimorbidity, particularly cardiorespiratory multimorbidity
  • Genetic epidemiology of lung function and respiratory disease
  • Mendelian randomisation for causal inference in epidemiology
  • Development of longitudinal population cohort studies
  • Predictors of occupational wellbeing in healthcare workers

Professor Martin Tobin

  • Investigation of the genetic determinants of common complex diseases and traits, including:
    • precision medicine
    • genome-wide studies of common and rare sequence variation
    • influence of copy number variation
    • lung function and respiratory disease
    • smoking cessation
    • cardiovascular disease and traits, particularly blood pressure
    • genomics in drug discovery, drug repositioning and stratified medicine
    • development and utilisation of new methods for the above studies

Mental Health, Ageing, Public Health and Primary Care (MAPP)

Professor Terry Brugha

  • Measurement (Psychopathology, Stressful Life Events, Social Networks, Autism in Adulthood)
  • Social Support Networks
  • Prevention of Depression
  • Evaluation of Services for the Severely Mentally Ill
  • Epidemiological Surveys of Mental Disorders including Autism Spectrum Disorders 

Professor Umesh Kadam

  • Heart failure
  • Multimorbidity
  • Ageing
  • Clinical epidemiology
  • Clinical informatics
  • Data science
  • Healthcare systems

Professor Alice Smith (Kidney Lifestyle Research Group)

We are engaged in a translational pathway, spanning experimental research through to implementation, centred on the key aims of improving/maintaining physical function and enabling/encouraging regular physical activity in Chronic Kidney Disease (CKD).

Overall we hypothesise that our proposed translational pathway will:

  • improve quality of life in CKD
  • improve patient health outcomes in CKD
  • reduce the healthcare and socio-economic cost burden of CKD

via impact on:

  • activities of daily living, self-care and employment
  • engagement in activities that are meaningful and important to the individual (hobbies, leisure activities, social activities)
  • independent living
  • ability to fulfil caring responsibilities for others eg spouse, parents, children
  • metabolic and cardiovascular health
  • cardiovascular events
  • co-morbidities
  • falls
  • deterioration of renal function in those whose CKD is associated with poor metabolic and/or vascular health
  • health and social care usage

Dr Chris Williams 

  • Older person’s care across primary, secondary, community and social care
  • Health systems, workforce development, quality and safety in primary care
  • Complex intervention studies and use of mixed methods
  • Primary care approaches to global health

Dr Kate Williams

  • Incontinence
  • Women's health
  • Qualitative research methods
  • Mixed methods research

Social Science Applied to Health Improvement Research (SAPPHIRE)

Professor Natalie Armstrong

  • Healthcare improvement research, particularly drawing on social science theory and methods
  • Population-based screening
  • Women’s and children’s health
  • Overdiagnosis, overtreatment, and overuse 

Dr Jennifer Creese

  • Healthcare workforce and human resources for health
  • Healthcare organisational culture and practice
  • Migrant and minority health experiences
  • Qualitative research; ethnography

Dr Kate Kirk

  • Healthcare workforce and wellbeing; emotion, work and regulation
  • Quality, safety and risk, knowledge translation and evidence based practice
  • Emergency and urgent care
  • Qualitative research and ethnography

Dr Nicola Mackintosh

  • contribution of patients and families to safety, particularly regarding escalation of care for life threatening illness
  • Service boundaries and their implications for patient journeys, safety and quality
  • e-health technologies and telemedicine, and changing patient-provider relationships
  • role of measurement in improvement and implementation science
  • ethnographies of health care work

Dr Mohammad Farhad Peerally

  • Use of mix methods to curate learning from patient safety incidents
  • Organisational responses following adverse events in healthcare
  • Applying high reliability theory to healthcare practice
  • Safety in Gastrointestinal endoscopy
  • Barrett's oesophagus screening

Professor Carolyn Tarrant

  • Influences on staff and patient behaviours related to prevention of healthcare associated infections and optimisation of antibiotic use
  • Patient experience of quality and safety in healthcare
  • Theory-based intervention development & evaluation
  • Qualitative Research; ethnography

The Infant Mortality and Morbidity Studies (TIMMS)

Professor Liz Draper

  • Data harmonisation and standardisation for preterm birth cohorts – both national and international
  • Outcomes from neonatal and paediatric intensive care
  • Surveillance and confidential enquiries into perinatal mortality and morbidity

Professor Samantha Johnson

  • Developmental psychology and psychopathology
  • Assessing neurodevelopmental outcomes in childhood
  • Long term neurodevelopmental outcomes after high risk birth
  • Educational outcomes after high risk birth

Dr Lucy Smith

  • Statistical methodology around the measurement and monitoring of adverse pregnancy outcomes
  • Qualitative research to understand parents’ and clinicians’ experiences of pregnancy loss, neonatal mortality and preterm birth
  • Use of large-scale routine health data to monitor and reduce inequalities in health 

Dr Brad Manktelow

  • The use of quantitative data for quality improvement in healthcare
  • Statistical process control (SPC) methodology applied to healthcare
  • Statistical methods for the routine reporting of healthcare quality indicators
  • The selection of quality indicators for quality assurance and quality improvement in healthcare

Professor Elaine Boyle

  • Effects of gestational age at birth on neonatal and later outcomes
  • Late preterm and early term birth
  • Assessment and management of neonatal pain
  • Enteral feeding in preterm infants
  • Neonatal randomised controlled trials

Dr Sarah Seaton

  • Epidemiology, experiences and outcomes following neonatal and/or paediatric intensive care
  • Outcomes and experiences following transport by paediatric critical care teams 
  • Supporting parents and families who have or had a critically ill child
     

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