Professor Melanie Davies

Professor of Diabetes Medicine

Profile

Professor Melanie Davies is the Director of the Leicester NIHR Biomedical Research Centre, Director of the Patient Recruitment Centre Leicester and a Professor in Diabetes Medicine. She has published over 550 original articles and has over £60m of grant funding. She was awarded a CBE in the 2016 New Year’s Honour’s List for services to diabetes research.

Professor Davies’ research interests include the causes, screening, prevention, self-management and treatment of type 2 diabetes mellitus. She is the Principal Investigator on a number of large global studies in the field of diabetes, obesity, physical activity, sedentary behaviour and cardiovascular disease.

The COVID-19 pandemic particularly impacts on people with cardiometabolic multimorbidity – those patients who have two or more of heart disease, stroke or diabetes. There is a higher risk still for people with type 2 diabetes and obesity who are from BAME groups.

The University of Leicester and the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre have world leading experts in respiratory disease and cardiometabolic conditions and a strong link to the NIHR’s Applied Research Centre East Midlands, based at Leicester Glenfield Hospital, which leads the multimorbidity research across England and hosts the Centre for BME Health.

Research

  • Diabetes
  • Obesity
  • Cardiovascular Disease
  • Sedentary Behaviour
  • Physical Activity

Publications

Patel N, Willis A, Stone M, Barber S, Gray L, Davies M, Khunti K. Developing a Conceptually Equivalent Type 2 Diabetes Risk Score for Indian Gujaratis in the UK. Journal of Diabetes Research 2016, 9 pages, Article ID 8107108 http://dx.doi.org/10.1155/2016/8107108

Simmons RK, Borch-Johnson K, Lauritzen T, Rutten GEHM, Sandbaek A, Van Den Donk M, Black J, Tao L, William E, Davies MJ, Khunti K, Sharp S, Wareham N, Griffin S. A randomised trial of the effect and cost-effectiveness of early intensive multifactorial therapy on five-year cardiovascular outcomes in individuals with screen-detected type 2 diabetes: the ADDITION-Europe study Health Technol Assess 2016 Aug;20(64):1-86. doi: 10.3310/hta20640 PMID: 27583404

Khunti K, Gillies C, Dallosso H, Brady E, Gray LJ, Kilgallen G, Willis A, Zafar A, Davies MJ. Assessment of response rates and yields for Two opportunistic Tools for Early detection of Non-diabetic hyperglycaemia and Diabetes (ATTEND). A randomised controlled trial and cost-effectiveness analysis. Diabetes Research and Clinical Practice (2016), Available Online 6th May 2016, doi:http://dx.doi.org/10.1016/j.diabres.2016.04.054

Dhalwani NN, Zaccardi F, O'Donovan G, Carter P, Hamer M, Yates T, Davies MJ, Khunti K. Association between lifestyle factors and the incidence of multimorbidity in an older English population. J Gerontol A Biol Sci Med Sci (2016) doi: 10.1093/gerona/glw146, First published online: July 28, 2016

Gray L, Yates T, Troughton J, Khunti K, Davies MJ. Engagement, retention, and progression to type 2 diabetes: a retrospective analysis of the cluster-randomized "Let's Prevent Diabetes" trial". PLoS Medicine 2016, July 12 http://dx.doi.org/10.1371/journal.pmed.1002078 [Accepted Article 3 June 2016]

Davies MJ, Chatterjee S, and Khunti K (2016). The treatment of type 2 diabetes in the presence of renal impairment: what we should know about newer therapies. Clinical Pharmacology: Advances and Applications. 2016 Jun 23;8:61-81. doi: 10.2147/CPAA.S82008. eCollection 2016 PMID: 27382388

Chatterjee S, Khunti K, Davies MJ. Optimizing Management of Glycaemia. Best Practice & Research: Clinical Endocrinology and Metabolism (2016), In Press, Accepted Manuscript, Available online 13 June 2016, doi:10.1016/j.beem.2016.06.002

Zaccardi F, Davies MJ, Dhalwani NN, Webb DR, Housley G, Shaw D, Hatton JW, Khunti K. Trends in hospital admissions for hypoglycaemia in England: a retrospective, observational study. Lancet Diabetes Endocrinol. 2016 Jun 9. pii: S2213-8587(16)30091-2. doi: 10.1016/S2213-8587(16)30091-2. [Epub ahead of print] PMID: 27293218

Khunti K, Chatterjee S, Carey M, Daly H, Batista-Ferrer H, and Davies MJ. New drug treatments versus structured education programmes for type 2 diabetes: comparing cost-effectiveness. Lancet Diabetes Endocrinol. 2016 May 24. Epub ahead of print. DOI: 10.1016/S2213-8587(16)30048

Rowlands AV, Yates T, Khunti K, Davies MJ, Edwardson CL. Raw accelerometer data analysis with GGIR R-package: Does accelerometer brand matter? Med Sci Sports Exerc. 2016 May 13. [Accepted Manuscript online]. DOI: 10.1249/MSS.0000000000000978. PMID: 27183118

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