Genetics
Behavioural Genetics
- Social evolution and social behaviour
- Reproductive conflicts in social groups
- Social insects
- Role of genes in behaviour
Professor Charalambos Kyriacou
- Molecular basis of circadian, tidal, and seasonal rhythms in arthropods
- Molecular genetics of aggression in drosophila
- Molecular analysis of electromagnetic sensitivity in insects and mammals
- Epigenetics
- Social insects
- Methylation
- Molecular neurobiology of complex behaviours in drosophila, especially circadian rhythms
- Molecular Investigation of diel vertical migration in Artic and Antarctic krill
- Genes, brain, and behaviour
- Identifying molecular mechanisms of behaviour using drosophila as a model system - research combines molecular genetics, bioinformatics, and population biology
Genetic Variation Mutation and Evolution
- Roles of retrotransposons (Mobile DNA Sequences) in genetic diversity, genetic disease, and genome evolution of Humans, non-human primates, and rodents
- Bioinformatics of high copy number repeats in the human genome
- Studying the genetic architecture, genotype-phenotype correlations, and evolution of complex traits in recently admixed populations
- Characterisation of the host-pathogen interactions underlying susceptibility to helicobacter pylori in recently admixed populations
- Investigation into the ethnic origins, demographic history, and contemporary legacies of the trans-Atlantic slave trade, using a combination of ancient DNA and modern DNA analyses
- Taxonomic and evolutionary studies in flowering plants, in particular the Saxifragaceae.
- Population genetics and molecular ecology of aquatic plants
- Causes and consequences of gene copy number variation
- Molecular evolution of Tyrosine Kinases
- Y-chromosomal, autosomal, and X-chromosomal haplotypes and the histories of human populations
- Mutation processes, including ectopic recombination and gene conversion
- Genetic genealogy
- Human meiotic tecombination processes and genome diversity
- Genome dynamics of mitochondrial DNA and nuclear insertions
Medical Genetics
- Exploring DNA sequence variation in humans by technology development, bioinformatics, and genotyping, to understand common disease aetiology, drug responses, genome structure/function, and population genetics
- Development and application of bioinformatic resources for the identification, re-use, and sharing of sequence variation data relating to inherited human diseases
- Genetic risks of ionizing radiation and chemical mutagens: germline mutation induction and radiation-induced genomic instability in irradiated human families and laboratory mice
- Molecular mechanisms of genome maintenance and cancer suppression
- Genetic control of cancer cell phenotypes that promote tumour development and evolution
- Exploiting genetic modifiers of neurodegenerative disease to elucidate mechanisms of pathogenesis and identify potential therapeutic strategies
- Telomere molecular dynamics in normal and immortal cells, including cells that use the alternative lengthening of telomeres mechanism
- Molecular mechanisms and consequences of Herpes virus integration and excision from telomeres
- Genetic prediction of radiotherapy response in breast, lung and prostate cancers
Microbial Genetics and Pathogenicity
- Gene regulation and host pathogen interactions by campylobacter jejuni
- Characterisation of chemotaxis signal transduction pathways
- Lipooligosaccharide biosynthesis
- Iron regulation
- Mechanistic basis for generation of mutations in tandem DNA repeat tracts of bacterial pathogens and their contributions to virulence, host adaptation and population structure
- Ecology and molecular biology of bacteriophages and their relationship with bacterial hosts
- Antimicrobial resistance and virulence mechanisms of staphylococcus aureus and streptococcus pneumoniae
- Phase variable epigenetic control as switchboard in microbial physiology and pathogenicity
Plant Biodiversity
- Developing and using tools for comparative and evo-devo analyses in plants
- Fruit/caryopsis development in crop species
- Molecular cytogentics, genomics, chromatin
- Biodiversity and its exploitation
- Bioinformatics, retrotransposons, repetitive DNA structure, evolution and function, cereals, bovids, model plant and animal species, tropical crops
- Crossover formation in model plants and crop species
- Cross kingdom analysis of meiotic chromosome behaviour
- Adaptation and evolution of meiosis in polyploids
- Genetic analysis of telomeres in yeast
- Genetics of yeast hybrids
- Exploiting natural genetic variation for yeast strain development
- Molecular and cell biology of plant sexual reproduction
- Functional studies of proteins regulating asymmetric cell division and germ cell specification
- Genome-wide studies of transcriptional and cell cycle networks in male gametogenesis
- Gene regulation by small RNAs
Plant Cell and Molecular Genetics
- Developing and using tools for comparative and evo-devo analyses in plants
- Fruit/caryopsis development in crop species
- Molecular cytogentics, genomics, chromatin
- Biodiversity and its exploitation
- Bioinformatics, retrotransposons, repetitive DNA structure, evolution and function, cereals, bovids, model plant and animal species, tropical crops
- Crossover formation in model plants and crop species
- Cross kingdom analysis of meiotic chromosome behaviour
- Adaptation and evolution of meiosis in polyploids
- Genetic analysis of telomeres in yeast
- Genetics of yeast hybrids
- Exploiting natural genetic variation for yeast strain development
- Molecular and cell biology of plant sexual reproduction
- Functional studies of proteins regulating asymmetric cell division and germ cell specification
- Genome-wide studies of transcriptional and cell cycle networks in male gametogenesis
- Gene regulation by small RNAs