Postgraduate research
Genetics
Behavioural Genetics
- Environmental factors and sleep regulation
- Circadian behaviours across Drosophila species
- Systems biology of neurogenesis
- Genomics and computational biology
- Evolutionary and developmental biology
- Genetic basis of variation in social organisation
Professor Charalambos Kyriacou
- Molecular basis of circadian, tidal, and seasonal rhythms in arthropods
- Molecular genetics of aggression in drosophila
- Molecular analysis of electromagnetic sensitivity in insects and mammals
- Ageing
- Epigenetics
- Social insects
- Methylation
- Molecular and functional investigations of complex behaviours in Drosophila, especially circadian rhythms
- Circadian clock and development
- Drosophila Cryptochrome and its role in physiology
Genetic Variation Mutation and Evolution
- Studying the genetic architecture, genotype-phenotype correlations, and evolution of complex traits in recently admixed populations
- Characterisation of the host-pathogen interactions underlying susceptibility to helicobacter pylori in recently admixed populations
- Tracing the evolutionary relationships of human microbial communities in genetically diverse populations
- Investigation into the demographic history, trait evolution and contemporary legacies of recent African migrations using a combination of ancient DNA and modern DNA analyses
- Systems biology of neurogenesis
- Genomics and computational biology
- Evolutionary and developmental biology
- Population genetics (in various species)
- Mathematical modelling of genetic diversity
- Bioinformatic approaches for whole genome sequencing data
- Taxonomic and evolutionary studies in flowering plants, in particular the Saxifragaceae
- Population genetics and molecular ecology of aquatic plants
- Population genetic effects of haplodiploidy
- Genetic basis of haplodiploidy
- Application of genetics to conservation
- Causes and consequences of structural variation in respiratory disease
- Structural variation in the asbestos-related cancer mesothelioma
- Human population, evolutionary and forensic genetics
- Animal forensics and conservation genetics
- Ecological and evolutionary epigenetics
- Transgenerational epigenetic inheritance
- Epigenetic consequences of pollution exposure
- Human meiotic recombination processes and genome diversity
- Genome dynamics of mitochondrial DNA and nuclear insertions
- Forensic genetics solutions for combatting wildlife crime
- Evolution of gene control networks, plant fertility, pollen, germ cells, biotechnology
- Sexual reproduction in model and crop plants
- Plant developmental biology
Medical Genetics
- Drosophila models of human diseases
- Sleep and health
- Exploiting genetic modifiers of neurodegenerative disease to elucidate mechanisms of pathogenesis and identify potential therapeutic strategies
- Causes and consequences of structural variation in respiratory disease
- Structural variation in the asbestos-related cancer mesothelioma
- Personalising breast cancer treatment according to predicted toxicity
- Radiogenomics and biomarkers
- Breast surgery and reconstruction
- Patients' views on breast cancer treatment and predictive testing
- Genetic prediction of radiotherapy response in breast, lung and prostate cancers
Microbial Genetics and Pathogenicity
- Exploring how genetic variation and slippery DNA in bacterial pathogens contributes to virulence, host adaptation and resistance to phages
- Characterisation of the host-microbe interactions underlying susceptibility to Helicobacter pylori in recently admixed populations
- Tracing the evolutionary relationships of human microbial communities in genetically diverse populations
Professor Martha Clokie
- Ecology and molecular biology of bacteriophages and their relationship with bacterial hosts
- Development of methods to study host-specific phageomes
- Induction of prophages in vivo
- Phage-based diagnostics
- Phage-based vaccines
- Discovery of phages infecting "exotic" bacteria
- Chemo-ecology of bacterial interactions
- Bacterial natural product biosynthesis, modification and utilization
Dr Spyridon Megremis
- Bacteriophage Biology, Bacteriophage Therapy, Microbial and viral ecology (microbiome, virome), Respiratory Science (chronic lung disease)
- My research focuses on the development of experimental systems (laboratory and computational) and research strategies to guide and support the implementation of phage therapy in chronic lung diseases
- Genomic diversity of bacteriophages
- Engineering of bacteriophages
- Phage-host interactions
- Antimicrobial resistance, host-pathogen interaction and environmental stress responses of respiratory bacteria including Staphylococcus aureus, Haemophilus influenzae and Moraxella catarrhalis
- Phase variable epigenetic control as switchboard in microbial physiology and pathogenicity
- Mining the bacterial lipoproteome to identify novel transcriptional regulators
- Molecular mechanisms shaping polymicrobial interactions and antibiotic resistance
- Bacterial communication and the switch between host species
Plant Biodiversity Cell and Molecular Genetics
- Molecular cytogentics, genomics, chromatin
- Biodiversity and its exploitation
- Bioinformatics, retrotransposons, repetitive DNA structure, evolution and function, cereals, bovids, model plant and animal species, tropical crops
- Crossover formation in model plants and crop species
- Cross kingdom analysis of meiotic chromosome behaviour
- Adaptation and evolution of meiosis in polyploids
- Evolution of gene control networks, plant fertility, pollen, germ cells, biotechnology
- Sexual reproduction in model and crop plants
- Plant developmental biology