I've worked at the University of Leicester since 2016, and have taught and researched on genetics and genomics, primarily focused on humans. I've particulalry enjoyed mentoring postgraduate researchs through my role as a supervisor and as postgraduate tutor. I've enjoyed outreach activities, including scientific advisor to the ITV drama "Code of a Killer", broadcast in 2015, with over 5 million viewers, which dramatises the invention of DNA fingerprinting and its first application to a criminal case by Alec Jeffreys here at Leicester.
My research interest is in the structural variation of genomes across species, populations, individuals and cells. My work focuses mostly on human genomes, with an interest in the mutational and evolutionary origins of structural variation, and its consequences for disease.
I have a long-standing interest in structural variation of genomic regions containing genes involved in immunity, and an interest in structural variation of the asbestos-related cancer mesothelioma, as part of the Leicester Mesothelioma Programme.
There is plenty of interesting research to be done that could form a PhD project in the area of structural variation, evolution or disease. I have recently supervised projects on structural variation of mesothelioma, genetic analysis of lung disease and structural variation analysis in large genomic datasets. For currently offered projects, search for "Hollox" on FindaPhD.com, but I'm happy to supervise projects across the spectrum of genome structural variation, so feel free to contact me by email to discuss potential projects in more detail.
I teach on many different courses across biological sciences on both evolutionary and medical aspects of genetics and genomics. These include first year molecular cell biology and genetics for medical students, first year Introductory Genetics, second year Genomes, and Genes Development and Inheritance, and third year Medical Genetics, Evolutionary Genetics and Human Genetics. I also supervise research projects for the MSc in Molecular Genetics and MSc in Bioinformatics.
Press and media
Human genetic variation disease or evolution.
BA(Hons) Natural Sciences, University of Cambridge
PhD Genetics, University College London
Senior Fellow of the Higher Education Academy
Fellow of the Royal Society of Biology