Professor Ed Hollox


School/Department: Genetics and Genome Biology, Department of

Telephone: +44 (0)116 252 3407



Dr Ed Hollox joined the University of Leicester in 2006 to teach and research genetics and genomics, primarily focusing on humans.

Dr Hollox has particularly enjoyed mentoring postgraduate researchers in the roles of supervisor and postgraduate tutor.

Dr Hollox has partaken in and enjoyed many outreach activities, including acting as scientific advisor to the ITV drama Code of a Killer, broadcast in 2015 and attracting over five million viewers, which dramatised the invention of DNA fingerprinting and its first application to a criminal case by Sir Alec Jeffreys FRS at the University of Leicester.


Dr Hollox’s main research interest is in the structural variation of genomes across species, populations, individuals and cells. This work is mainly focused on human genomes, with an interest in the mutational and evolutionary origins of structural variation, and its consequences for disease.

Dr Hollox has a long-standing interest in structural variation of genomic regions containing genes involved in immunity, and an interest in structural variation of the asbestos-related cancer mesothelioma, as part of the Leicester Mesothelioma Programme.


For a list of my research publications, please click on the link below to search for me on Pubmed.


I am also an author of the textbook Human Evolutionary Genetics.


There is plenty of interesting research to be done that could form a PhD project in the area of structural variation, evolution or disease.

Dr Hollox has recently supervised projects on structural variation of mesothelioma, genetic analysis of lung disease and structural variation analysis in large genomic datasets.

For currently offered projects, search for "Hollox" on, but Dr Hollox is happy to supervise projects across the spectrum of genome structural variation, and welcomes contact by email to discuss potential projects in more detail.


Dr Hollox teaches on many different courses across biological sciences on both evolutionary and medical aspects of genetics and genomics. These include first year molecular cell biology and genetics for medical students, first year Introductory Genetics, second year Genomes, and Genes Development and Inheritance, and third year Medical Genetics, Evolutionary Genetics and Human Genetics.

Dr Hollox also supervises research projects for the MSc in Molecular Genetics and MSc in Bioinformatics. 

Press and media

The effects of human genetic variation on disease and evolution.


BA(Hons) Natural Sciences, University of Cambridge

PhD Genetics, University College London

Senior Fellow of the Higher Education Academy

Fellow of the Royal Society of Biology

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