People
Professor Eamonn Mallon
Professor of Evolutionary Biology, Associate Dean of Research
School/Department: Genetics and Genome Biology, Department of
Telephone: +44 (0)116 252 3488
Email: ebm3@leicester.ac.uk
Profile
Eamonn Mallon was born in Dublin and attended Trinity College Dublin completing a BA (Mod.) in Zoology, going on to study for a PhD in ant colony self-organisation with Professor Nigel Franks at the University of Bath.
A move to Switzerland and bumblebees followed to work with Professor Paul Schmid-Hempel at the ETH Zurich. At the ETH, Professor Mallon studied the role of immunity in pollinator behaviour.
This continued when Professor Mallon took up a position at the University of Leicester, where current research involves studying epigenetic factors in social insects.
Research
Epigenetics is defined as the heritable change in expression of a gene without any change in the DNA sequence. Everything we do - diet, habitat, social interactions, even aging - causes chemical modifications on genes that will turn those genes on or off: epigenetic changes. Many diseases including cancer and Alzheimer's show epigenetic changes between the normal or healthy state.
Professor Mallon’s group research epigenetics in insects, mainly bumblebees and wasps. This is done both as a model of more complicated systems, e.g. humans, and because of insects’ importance to humanity’s survival. For example, insect pollination services are worth 14.2 billion euros to Europe's economy.
Visit https://le.ac.uk/social-epigenetics-lab for more details
Publications
Pozo, M., Hunt, B.J., Mallon, E.B. et al. (2021) The effect of DNA methylation on bumblebee colony development. BMC Genomics 22, 73
Marshall, H. van Zweden, J.S., Van Geystelen, A., Benaets, K., Wäckers, F., Mallon, E.B. & Wenseleers, T. (2020) Genome-wide search for parent-of-origin allele specific expression in Bombus terrestris. Evolution Letters 4 (6), 479-490
Marshall, H., Jones, A.R.C., Lonsdale, Z.N., & Mallon, E.B. (2020) Bumblebee worker castes show differences in allele-specific DNA methylation and allele-specific expression. Genome Biology and Evolution 12 (8), 1471-1481
Jones, A.R.C. & Mallon, E.B. (2020) Evidence of capacitation in the parasitoid wasp, Nasonia vitripennis and its potential role in sex allocation Ecology and Evolution 0:1-9
Hunt, B.J., Mallon, E.B. & Rosato E. (2019) In silico identification of a molecular circadian system with novel features in the crustacean model organism Parhyale hawaiensis. Frontiers in Physiology.10, p 1325
Marshall, H., Lonsdale, Z.N., & Mallon, E.B. (2019) Methylation and Gene Expression Differences Between Reproductive Castes of Bumblebee Workers. Evolution Letters. 3(5), pp 485-499.
Harrison, M.C., Mallon, E.B., Twell, D. & Hammond, R.L. (2019) Deleterious mutation accumulation in Arabidophis thaliana pollen genes: a role for a recent relaxation of selection. Genome Biology and Evolution Volume 11, Issue 7 Pages 1939-1951.
Bebane, P., Hunt, B.J. Pegoraro, M., Jones, A. M., Marshall, H., Rosato, E., & Mallon, E.B. (2019) The neonicotinoid, imidicloprid affects gene expression and methylation in the buff-tailed bumblebee Bombus terrestris. Proc. R. Soc. B Biol. Sci. 286 (1905)
Price, J., Harrison, M.C., Hammond, R.L., Adams, S., Gutierrez-Marcos J.F., & Mallon, E.B. (2018) Alternative splicing associated with phenotypic plasticity in the bumble bee Bombus terrestris Molecular Ecology 27 (4) pp 1036-1043
Lonsdale, Z.N., Lee, K.D., Kyriakidou, M., Amarasinghe, H.E., Nathanael, D., O'Connor, C.J. & Mallon, E.B. (2017) Allele specific expression and methylation in the bumblebee, Bombus terrestris . PeerJ 5:e3798
Supervision
Social insects
Social evolution
Epigenetics
Pesticides
Teaching
Professor Mallon teaches the statistical components of the first year course in modules BS1040, BS1070 and MB1080, and convenes the second year module BS2004, Contemporary techniques in biological data analysis.
Press and media
Insects
Evolution
Epigenetics
Qualifications
- 1997-2001: PhD, University of Bath (Supervisor: Nigel Franks)
- 1992-1997: BA (Hons), Trinity College Dublin, Natural Sciences (Zoology)