People

Dr Ed Galyov

Reader

School/Department: Genetics and Genome Biology Department of

Telephone: +44 (0)116 252 2980

Email: eg98@leicester.ac.uk

Profile

"Current post (since Oct 2007): Reader Education/Degrees: BSc MSc. (Chemistry) 1985 Leningrad (St. Petersburg) University Russia PhD. (Molecular Biology) 1990 Institute of Molecular Biology Russian Acad. Sci. Moscow Russia"

Research

"Phage biology Phage therapy Interactions of bacterial pathogens with host cells and phages Environmental biology of bacterial pathogens Burkholderia pseudomallei Pseudomonas aeruginosa E. coli Salmonella Staphylococcus aureus"

Publications

(0) "Galyov E.E. Håkansson S. Forsberg Å. and Wolf-Watz H. 1993. A secreted protein kinase of Yersinia pseudotuberculosis is an indispensable virulence determinant. Nature 361(6414) pp.730-732. Galyov E.E. Wood M.W. Rosqvist R. Mullan P.B. Watson P.R. Hedges S. and Wallis T.S. 1997. A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa. Molecular microbiology 25(5) pp.903-912. Stevens M.P. Wood M.W. Taylor L.A. Monaghan P. Hawes P. Jones P.W. Wallis T.S. and Galyov E.E. 2002. An Inv/Mxi‐Spa‐like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Molecular microbiology 46(3) pp.649-659. Stevens M.P. Stevens J.M. Jeng R.L. Taylor L.A. Wood M.W. Hawes P. Monaghan P. Welch M.D. and Galyov E.E. 2005. Identification of a bacterial factor required for actin‐based motility of Burkholderia pseudomallei. Molecular microbiology 56(1) pp.40-53. Galyov E.E. Brett P.J. and DeShazer D. 2010. Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis. Annual review of microbiology 64 pp.495-517. Shan J. Korbsrisate S. Withatanung P. Adler N.L. Clokie M.R. and Galyov E.E. 2014. Temperature dependent bacteriophages of a tropical bacterial pathogen. Frontiers in microbiology 5 p.599. Lazar Adler N.R. Stevens M.P. Dean R.E. Saint R.J. Pankhania D. Prior J.L. Atkins T.P. Kessler B. Nithichanon A. Lertmemongkolchai G. and Galyov E.E. 2015. Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice net intracellular replication and a novel protein conferring serum resistance. PLoS One 10(4) p.e0121271. Egilmez H.I. Morozov A.Y. Clokie M.R. Shan J. Letarov A. and Galyov E.E. 2018. Temperature-dependent virus lifecycle choices may reveal and predict facets of the biology of opportunistic pathogenic bacteria. Scientific reports 8(1) pp.1-13. Imam M. Alrashid B. Patel F. Dowah A.S. Brown N. Millard A. Clokie M.R. and Galyov E.E. 2019. vB_PaeM_MIJ3 a novel jumbo phage infecting Pseudomonas aeruginosa possesses unusual genomic features. Frontiers in microbiology p.2772. Egilmez H.I. Morozov A.Y. and Galyov E.E. 2021. Modelling the spatiotemporal complexity of interactions between pathogenic bacteria and a phage with a temperature-dependent life cycle switch. Scientific reports 11(1) pp.1-13. ".

Supervision

"Phage biology Phage therapy Interactions of bacterial pathogens with host cells and phages Environmental biology of bacterial pathogens"

Teaching

"MB3020 Advanced Topics in Medical Microbiology (Convenor) MB2020 Medical Microbiology BS1040 Microbiology and Cell Biology (practicum) BS3X00 3rd year projects (Departmental coordinator)"

Press and media

"Phage biology Russian science"
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