Professor Nicola Cooper

Professor of Healthcare Evaluation Research

School/Department: Population Health Sciences, Department of

Telephone: +44 (0)116 229 7267



I am Professor of Healthcare Evaluation Research at the University of Leicester and Deputy Director of the NIHR-funded Complex Reviews Support Unit ( My primary research interest is in the interface and integration of medical statistics and health economics.

My areas of research include:

· Health technology assessment

· Evidence synthesis (including network meta-analysis and diagnostic test accuracy) and its integration within a decision modelling context

· Data visualisation in health technology assessment

· Economic evaluation alongside clinical trials

· Bayesian methods in healthcare


Web-based tools developed by the Complex Reviews Support Unit (CRSU):

MetaInsight: An interactive web-based tool for the analysis and interrogation of network meta-analyses (frequentist and Bayesian).

· Binary: · Continuous:

MetaDTA: An interactive web-based tool for the analysis and interrogation of diagnostic test accuracy meta-analyses



Xin Y, Nevill C, Nevill J, Gray E, Cooper NJ, Bradbury N, Sutton AJ. Feasibility study for interactive reporting of network meta-analysis: Experiences from the development of the MetaInsight COVID-19 app for stakeholder exploration, re-analysis and sensitivity analysis from living systematic reviews. BMC Medical Research Methodology.

Freeman SC, Cooper NJ, Sutton AJ, Crowther MJ, Carpenter JR, Hawkins N. Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: application to a melanoma network. Statistical Methods in Medical Research 2022 doi:10.1177/09622802211070253

March DS, Hurt AW, Grantham CE, Churchward DR, Young HML, Highton PJ, Dungey M, Bishop NC, Smith AC, Graham-Brown MPM, Cooper NJ, Burton JO. A cost-effective analysis of the CYCLE-HD randomised controlled trial. Kidney International Reports. 2021; 6(6): 1548-1557.

Quinn TJ, Burton JK, Carter B, Cooper NJ, Dwan K, Field R, Freeman SC, Geue C, Hsieh PH, McGill K, Nevill CR, Rana D, Sutton A, Rowan MT, Xin Y. Following the Science? Comparison of the methodological and reporting quality of covid-19 and other research. BMC Medicine 2021; 19(46).

Smith E, Cooper NJ, Sutton AJ, Abrams KRA, Hubbard SJ. A Review of the Quantitative Effectiveness Evidence Synthesis Methods Used in Public Health Intervention Guidelines. BMC Public Health. 2021; 278.

Cerullo E, Quinn T, McCleery J, Vounzoulaki E, Cooper NJ, Sutton A.  Interrater agreement in dementia diagnosis: a systematic review and meta-analysis. International Journal of Geriatric Psychiatry. 2021. (

Patel A, Cooper NJ, Freeman SC, Sutton AJ. Graphical Enhancements to Summary Receiver Operating Characteristic (SROC ) Plots to Facilitate the Analysis and Reporting of Meta-analysis of Diagnostic Test Accuracy Data. Research Synthesis Methods 2021; 12(1) (

Owen R, Bradbury N, Xin Y, Cooper NJ, Sutton AJ. MetaInsight: An interactive web-based tool for analyzing, interrogating and visualizing network meta-analyses using R-shiny and netmeta. Research Synthesis Methods. 2019. 99: 64-74. DOI: 10.1016/j.jclinepi.2018.03.005

Freeman SC, Kerby CR, Patel A, Cooper NJ, QuinnT, Sutton AJ. Development of an interactive web-based tool to conduct and interrogate meta-analysis of diagnostic test accuracy studies: MetaDTA. BMC Medical Research Methodology 2019. 19(81) 10.1186/s12874-019-0724-x

Cooper NJ, Kendrick D, Timblin C, Hayes M, Majsak-Newman G, Meteyard K, Hawkins A, Kay B. The short-term cost of falls, poisonings and scalds occurring at home in children under 5 years old in England: multicenter longitudinal study.  Injury Prevention  2016. doi:10.1136/injuryprev-2015-041808



M.Sc. in Medical Statistics


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