Dr Lauren O'Mahoney

Lauren is a Research Associate within the UK National Institute for Health Research (NIHR) in Applied Research Collaborations (ARC) East Midlands team. Based in the Diabetes Research Centre at Leicester General Hospital, her expertise include diabetes and metabolic health, cardiometabolic disease, and multiple long-term conditions.

Lauren is primarily working on a NIHR ARC-EM funded project investigating an electronic decision-support system for the deintensification of potentially inappropriate medications amongst older frail people with type 2 diabetes. In addition Lauren is currently working on a range of projects within her team in relation to type 2 diabetes, multimorbidity, and Long Covid. 

Throughout the Coronavirus pandemic Lauren has contributed to Long Covid related research and continues to be a member of the National Long Covid Research Working Group led by Professor Kamlesh Khunti.

Academic peer-reviewed journal articles

O'Mahoney LL, Routen A, Gillies C, Ekezie W, Welford A, Zhang A, Karamchandani U, Simms-Williams N, Cassambai S, Ardavani A, Wilkinson TJ, Hawthorne G, Curtis C, Kingsnorth AP, Almaqhawi A, Wrd T, Ayoubkhani D, Banerjee A, Calvert M, Shafran R, Stephenson T, Sterne J, Ward H, Evans RE, Zaccardi F, Wright S, Khunti K. The prevalence and long-term health effects of Long Covid among hospitalised and non-hospitalised populations: a systematic review and meta-analysis. eClinicalMedicine. 2023; 55: 101762.

Behnood SA, Shafran R, Bennett SD, Zhang AXD, O'Mahoney LL, Stephenson TJ, et al. Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies. J Infect. 2022;84(2):158-70.

Campbell MD, West DJ, O'Mahoney LL, Pearson S, Kietsiriroje N, Holmes M, et al. The relative contribution of diurnal and nocturnal glucose exposures to HbA1c in type 1 diabetes males: a pooled analysis. J Diabetes Metab Disord. 2022;21(1):573-81.

Coales EM, Ajjan RA, Pearson SM, O'Mahoney LL, Kietsiriroje N, Brož J, et al. Application of Machine Learning to Assess Interindividual Variability in Rapid-Acting Insulin Responses After Subcutaneous Injection in People With Type 1 Diabetes. Can J Diabetes. 2022;46(3):225-32.e2.

Hafiz MS, Campbell MD, O'Mahoney LL, Holmes M, Orfila C, Boesch C. Pulse consumption improves indices of glycemic control in adults with and without type 2 diabetes: a systematic review and meta-analysis of acute and long-term randomized controlled trials. Eur J Nutr. 2022;61(2):809-24.

Howard E, Attenbourgh A, O'Mahoney LL, Sakar A, Ke L, Campbell MD. Postprandial vascular-inflammatory and thrombotic responses to high-fat feeding are augmented by manipulating the lipid droplet size distribution. Nutr Metab Cardiovasc Dis. 2021;31(9):2716-23.

Kietsiriroje N, Pearson SM, O'Mahoney LL, West DJ, Ariëns RA, Ajjan RA, et al. Glucose variability is associated with an adverse vascular profile but only in the presence of insulin resistance in individuals with type 1 diabetes: An observational study. Diab Vasc Dis Res. 2022;19(3):14791641221103217.

O'Mahoney LL, Churm R, Stavropoulos-Kalinoglou A, Ajjan RA, Orsi NM, Mappa G, et al. Associations Between Erythrocyte Membrane Fatty Acid Compositions and Biomarkers of Vascular Health in Adults With Type 1 Diabetes With and Without Insulin Resistance: A Cross-Sectional Analysis. Can J Diabetes. 2022;46(2):111-7.

O'Mahoney LL, Dunseath G, Churm R, Holmes M, Boesch C, Stavropoulos-Kalinoglou A, et al. Omega-3 polyunsaturated fatty acid supplementation versus placebo on vascular health, glycaemic control, and metabolic parameters in people with type 1 diabetes: a randomised controlled preliminary trial. Cardiovasc Diabetol. 2020;19(1):127.

O'Mahoney LL, Highton PJ, Kudlek L, Morgan J, Lynch R, Schofield E, et al. The impact of the COVID-19 pandemic on glycaemic control in people with diabetes: A systematic review and meta-analysis. Diabetes Obes Metab. 2022;24(9):1850-60.

O'Mahoney LL, Kietsiriroje N, Pearson S, West DJ, Holmes M, Ajjan RA, et al. Estimated glucose disposal rate as a candidate biomarker for thrombotic biomarkers in T1D: a pooled analysis. J Endocrinol Invest. 2021;44(11):2417-26.

O'Mahoney LL, Matu J, Price OJ, Birch KM, Ajjan RA, Farrar D, et al. Omega-3 polyunsaturated fatty acids favourably modulate cardiometabolic biomarkers in type 2 diabetes: a meta-analysis and meta-regression of randomized controlled trials. Cardiovasc Diabetol. 2018;17(1):98.

Stephenson T, Pinto Pereira SM, Shafran R, de Stavola BL, Rojas N, McOwat K, et al. Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study. Lancet Child Adolesc Health. 2022;6(4):230-9.

Wilkinson TJ, O'Mahoney LL, Highton P, Viana JL, Ribeiro HS, Lightfoot CJ, et al. Physical activity and the 'pediatric inactivity triad' in children living with chronic kidney disease: a narrative review. Ther Adv Chronic Dis. 2022;13:20406223221109971.

Other scholarly publications

O'Mahoney L, Khunti K. Long covid: risk factors, outcomes, and future directions for research. BMJ Medicine. 2022;1(1):e000257.

Routen A, O’Mahoney L, Ayoubkhani D, Banerjee A, Brightling C, Calvert M, et al. Understanding and tracking the impact of long COVID in the United Kingdom. Nature Medicine. 2022;28(1):11-5.