Dr Thomas Wilkinson

I am a Research Fellow based in the NIHR Applied Research Collaboration (ARC) East Midlands based in the Leicester Diabetes Centre Leicester General Hospital. My research focuses on multiple long-term conditions and multimorbidity with a specific interest in frailty sarcopenia and kidney disease. I have a background in exercise physiology and I am interested in the role of lifestyle interventions in those living with chronic disease. I am a current member of the College of Life Sciences Mirror College Leadership Team.

 

I am a member of the Global Renal Exercise Group Organising Committee Member (Scientific Director) and UK ‘Exercise and Lifestyle’ CSG having recently co-authored the UKKA Exercise and lifestyle CPG in kidney disease. I am a contributor to the ‘Movement for Movement’’ resources and ‘Physical Activity: A Guide for Health Practitioners’ on kidney disease. I have been an invited presented to meetings around the world. I contribute teaching to the University of Leicester and Loughborough University and have external examined grants and postgraduate theses for UK and international institutions. I am a peer-reviewer for numerous high impact journals.

My research aims to address how to improve the health and well-being of people living with chronic disease. The majority of my work has focused on the role of lifestyle (e.g. physical activity) interventions as means to improve physical function and well-being. I have also conducted research into investigating the optimisation of measuring physical function in chronic disease e.g. kidney disease and have an interest in clinimetric properties. I have received funding from Kidney Research UK Kidney Care Appeal Renal Association and European Renal Association- European Dialysis Transplant Association.

h-index 21          i10-index 39          

 

2023 [n=14]

• Greenwood SA, et al. Evaluating the effect of a digital health intervention to enhance physical activity in people with chronic kidney disease (Kidney BEAM): A multi-centre, randomised controlled trial. Lancet Digital Medicine [IF: 30.8] 2023. In press

• Wilkinson TJ, Gore EF, Baker LA, Smith AC. Viscoelastic skeletal muscle properties and the association with physical performance in chronic kidney disease. Physiologia 2023, 3(3), 451-460. DOI: https://doi.org/10.3390/physiologia3030032

   

• Barbosa AC, Brison R, Gomes C, Wilkinson TJ, Duarte MP, Gruezo N, Ribeiro HS. Should We Consider Sarcopenia in Pediatric Patients with Chronic Kidney Disease? A Preliminary Cross-sectional Analysis. Pediatric Nephrology [IF: 3.4] 2023. In press

   

• MacRae J, Harasemiw O, Lightfoot CJ, Wytsma-Fisher K, Koufaki P, Robertson HL, Bohm C, Thompson S, Wilkinson TJ. Measurement properties of performance-based measures to assess physical function in chronic kidney disease: recommendations from a COSMIN systematic review. Clinical Kidney Journal [IF: 5.860] 2023, sfad170. DOI: doi.org/10.1093/ckj/sfad170

   

• Coyne E, Briggs J, Loud F, Bristow P, Young HML, Castle EM, Lightfoot CJ, Graham-Brown M, Eyre M, Ormandy P, Sachar A, Bevin A, Burton J, Wilkinson TJ, Koufaki P, Macdonald J, Ashman N, Greenwood SA. Achieving consensus on psychosocial and physical rehabilitation management for people living with kidney disease. Clinical Kidney Journal [IF: 5.860] 2023, sfad116. DOI: https://doi.org/10.1093/ckj/sfad116

   

• Greenwood SA, Oliveria BA, Asgari E, Ayis S, Baker LA, N Beckley-Hoelscher, Goubar A, Banerjee D, Bhandari S, Chilcot J, Burton JO, Kalra PA, Lightfoot CJ, Macdougall IC, McCafferty K, Mercer TH, Okonko DO, Reid C, Reid F, Smith AC, Swift PA, Watson E, Wheeler DC, Wilkinson TJ, Bramham K. A Randomized Trial of Intravenous Iron Supplementation and Exercise on Exercise Capacity in Iron-Deficient Nonanemic Patients With CKD. Kidney International Reports [IF: 6.234]. DOI: https://doi.org/10.1016/j.ekir.2023.05.002

   

• Wilkinson TJ, MacRae J, Thompson S, Bohm C. Making the case for standardized outcome measures in exercise and physical activity research in chronic kidney disease. Kidney and Dialysis 2023, 3(2), 219-228. DOI: https://doi.org/10.3390/kidneydial3020020

   

• Walkin CG, Young HML, Asghari E, Bhandari S, Billany RE, Bishop N, Bramham K, Briggs J, Burton JO, Campbell J, Castle EM, Chilcot J, Cooper N, Deelchand V, Graham-Brown MPM, Hamilton A, Jesky M, Kalra PA, Koufaki P, Macafferty K, Nixon AC, Noble H, Saynor ZL, Sothinathan C, Taal M, Wheeler D, Wilkinson TJ, Macdonald JM, Greenwood SA. The effect of a novel, digital physical activity and emotional well-being intervention on health-related quality of life in people with chronic kidney disease: study design and baseline data from a multicentre prospective, wait-list randomised controlled trial (Kidney BEAM). BMC Nephrology. In press

   

• Hawthorne G, Lightfoot CL, Smith AC, Khunti K, Wilkinson TJ. Multimorbidity prevalence and patterns in chronic kidney disease: findings from an observational multicenter UK cohort study. International Urology and Nephrology [IF: 2.12] 2023. DOI : 10.1007/s11255-023-03516-1

   

• Lightfoot CJ, Wilkinson TJ, Smith AC. Non-pharmacological management of chronic kidney disease. Medicine [IF: 1.899] 2023. DOI: 10.1016/j.mpmed.2022.12.004

   

• Goes CR, Vogt BP, Biruete A, Wilkinson TJ, Snelson M. Editorial: Nutrition and Metabolism in Kidney Diseases. Frontiers in Nutrition [IF: 6.590] 2023, 10. DOI: 10.3389/fnut.2023.1088977

   

• Ardavani A, Curtis F, Khunti K, Wilkinson TJ. The effect of pharmacist-led interventions on the management and outcomes in chronic kidney disease: a systematic review and meta-analysis protocol. Health Science Reports 2023 DOI:10.1002/hsr2.1064.

   

• Seidu S, Abdool M, Almaqhawi A, Wilkinson TJ, Kunutsor SK, Khunti K. Physical activity and risk of chronic kidney disease: systematic review and meta-analysis of 12 cohort studies involving 1,281,727 participants. European Journal of Epidemiology [IF: 12.434] 2023. DOI: 10.1007/s10654-022-00961-7

   

• O'Mahoney L, Routen A, Winifred E, Welford A, Chang C, Karamchandani U, Simms-Williams N, Cassambai S, Ardavani A, Wilkinson TJ, Hawthorne G, Curtis F, Kingsnorth A, Almaqhawi A. Ward T, Ayoubkhani D, Banerjee A, Calvert M, Shafran R, Stephenson T, Sterne J, Ward H, Evans R, Gillies C, Khunti K. A systematic review of the prevalence and long-term health effects of Long Covid among the general hospitalised and non-hospitalised population. eClinicalMedicine [IF: 17.033] 2023, 55(1010762). DOI: https://doi.org/10.1016/j.eclinm.2022.101762

   

  2022 [n=14]

   

• Mickute M, Zaccardi F, Razieh C, Sargeant J, Smith AC, Wilkinson TJ, Young HL, Webb D, Khunti K, Davies MJ, Yates T. Individual frailty phenotype components and mortality in adults with type 2 diabetes: A UK Biobank study. Diabetes Research and Clinical Practice [IF: 6.59] 2022, 24;195:110155. DOI: 10.1016/j.diabres.2022.110155.

   

• Lightfoot CJ*, Wilkinson TJ*, Yates T, Davies M, Smith AC. Self-Management Intervention through Lifestyle Education for Kidney health’ (the SMILE-K study): protocol for a single-blind longitudinal randomised control trial with nested pilot study. BMJ Open [IF: 3.007] 2022. DOI: 10.1136/bmjopen-2022-064916

   

• Lightfoot CJ, Wilkinson TJ, Hadjiconstantinou M, Graham-Brown M, Barratt J, Brough C, Burton JO, Hainsworth J, Johnson V, Martinez M, Nixon AC, Pursey V, Schreder S, Vadaszy N, Wilde L, Willingham F, Young HML, Yates T, Davies MJ, Smith AC. The co-development of ‘My Kidneys & Me’: a digital self-management programme for people with chronic kidney disease. J Med Internet Res [IF: 7.08] 2022, 24(11):e39657. DOI: doi:10.2196/39657

   

• Greenwood SA, Beckley-Hoelscher N, Asgari E, Ayis S, Baker LA, Banerjee D, Bhandari S, Branham K, Chilcot J, Burton J, Kalra PA, Lightfoot CJ, McCafferty K, Mercer TH, Okonko DO, Oliveria B, Reid C, Smith AC, Swift P, Mangelis A, Watson E, Wheeler DC, Wilkinson TJ, Reid F, Macdougall IC. The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial. BMC Nephrology [IF: 2.126] 2022, 23: 268. DOI: 10.1186/s12882-022-02896-3

   

• Wilkinson TJ: Miksza J; Zaccardi F; Lawson C; Nixon AC: Young HML; Khunti K; Smith AC. Frailty and cardiovascular, renal, and mortality outcomes among people with chronic kidney disease: a retrospective cohort study using electronic health records. J Cachexia Sarcopenia Muscle [IF: 12.9]. DOI: https://doi.org/10.1002/jcsm.13047

   

• Wilkinson TJ, O’Mahoney LO, Highton P, Viana JL, Ribeiro HS, Lightfoot CL, Curtis F, Khunti K. Physical activity and the ‘pediatric inactivity triad’ in children living with chronic kidney disease: a narrative review. Therapeutic Advances in Chronic Disease 2022 [IF: 5.621], 13, 1-15. DOI: 10.1177/20406223221109971

   

  *Invited review

   

• March DS, Wilkinson TJ, Burness T, Billany RE, Jackson K, Baker LA, Thomas A, Robinson KA, Watson EL, Graham-Brown MPM, Jones AW, Burton JO. The effect of non-pharmacological and pharmacological interventions on measures associated with sarcopenia in end-stage kidney disease: A systematic review and meta-analysis. Nutrients 2022 [IF: 5.719], 14(9), 1817. DOI: 10.3390/nu14091817

- Memory KE, Lightfoot CJ, Wilkinson TJ, Smith AC. A qualitative exploration of the facilitators and barriers to self-management in kidney transplant recipients. Journal of Nephrology. Accepted

- Lightfoot CL; Nair D; Bennett PN; Smith AC; Griffin AD: Warren M; Wilkinson TJ. Patient activation: the cornerstone of effective self-management in chronic kidney disease? Kidney and Dialysis 2022, 2(1), 91-105. DOI: 10.3390/kidneydial2010012

- Baker LA, March DS, Wilkinson TJ, Billany RE, Bishop NC, Castle EM, Chilcot J, Davies MD, Graham-Brown MPM, Greenwood SA, Junglee NA, Kanavaki AM, Lightfoot CJ, Macdonald JH, Rossetti GMK, Smith AC, Burton JO. Clinical practice guideline exercise and lifestyle in chronic kidney disease. BMC Nephrology [IF: 2.216] 2022, 23(75). DOI: 10.1186/s12882-021-02618-1

- Moore C; Santhakumaran S, Martin G, Wilkinson TJ, Caskey F, Magadi W, Gair R, Smith AC, Wellsted D; van der Veer SN. Symptom clusters in chronic kidney disease and their association with people’s ability to perform usual activities. PLoS ONE [IF: 3.24] 2022, 17(3): e0264312. DOI: 10.1371/journal.pone.0264312

- Wilkinson TJ, Ribeiro HS. Recognizing the importance of physical activity on sarcopenia in chronic kidney disease. Osteoporosis and Sarcopenia 2022, 8(1): 30-31. DOI: 10.1016/j.afos.2022.02.002

- Kanavaki AM, Lightfoot CJ, Palmer J, Wilkinson TJ, Smith AC, Jones CR. Kidney care during COVID-19 in the UK: perspectives of healthcare professionals on impacts on care quality and staff well-being. International Journal of Environmental Research and Public Health [IF: 3.390] 2022; 19 (188). DOI:  10.3390/ijerph19010188

- Wilkinson TJ, Lightfoot CJ, Palmer J, Smith AC. Navigating the COVID-19 infodemic in those living with kidney disease: access and trust in health information sources and the association with anxiety and depression. Current Medical Research & Opinion [IF: 2.580] 2022; 38 (1): 35-42. DOI: 10.1080/03007995.2021.1984221

2021 [21]

- Wilkinson TJ, Lightfoot CJ, Smith AC, Khunti K, Zaccardi F. Association of ethnicity and socioeconomic status with COVID-19 hospitalisation and mortality in those with and without chronic kidney disease. Kidney International Reports [IF: 4.164] 2021. DOI: 10.1016/j.ekir.2021.11.040 

- Mayes J, Billany R, Vasadzy N, Young H, Castle E, Bishop NC, Bramham K, Nixon A, Wilkinson TJ, Hamilton A, Saynor Z, Chilcot J, Macdonald JH, Picariello F, Greenwood SA. The rapid development of a novel kidney-specific digital intervention for self-management of physical activity and emotional wellbeing during the COVID-19 pandemic and beyond: Kidney Beam. Clinical Kidney Journal [IF: 4.452] 2021. DOI: 10.1093/ckj/sfab239

- Wilkinson TJ, Bishop NC, Billany RE, Lightfoot CJ, Castle EM, Smith AC, Greenwood SA. The effect of exercise training interventions in adult kidney transplant recipients: a systematic review and meta-analysis of randomised control trials. Physical Therapy Reviews 2021. DOI: 10.1080/10833196.2021.2002641

- Watson EL, Baker LA, Wilkinson TJ, Gould DW, Xenophontos S, Graham-Brown M, Major RW, Ashford RU, Viana JL, Smith AC. Inflammation and physical dysfunction: responses to moderate intensity exercise in chronic kidney disease. Nephrology Dialysis Transplantation [IF: 5.992] 2021. DOI: 10.1093/ndt/gfab333

- Lightfoot CJ, Wilkinson TJ, Palmer J, Kanavaki AM, Smith AC. Patient and staff experiences of remote kidney healthcare: lessons learnt from COVID-19. Journal of Nephrology [IF: 3.9] 2021. DOI: 10.1007/s40620-021-01175-y 

- Billany RE, Vadaszy N, Bishop NC, Wilkinson TJ, Adenwalla SF, Robinsion KA, Croker K, Brady EM, Wormleighton J, Parke K, Cooper NJ, Webster AC, Barratt J, McCann GP, Burton JO, Smith AC, Graham-Brown MPM. A pilot randomised controlled trial of a structured, home-based exercise program on cardiovascular structure and function in kidney transplant recipients: The ECSERT study design and methods. BMJ Open [IF: 2.496] 2021. DOI: 10.1136/bmjopen-2020-046945

- Bennett PN, Kohzuki M, Bohm C, Roshanravan B, Bakker SJL, Viana JL, MacRae JM, Wilkinson TJ, Wilund KR, Van Craenenbroeck AH, Sakkas GK, Mustata S, Fowler K, Macdonald J, Aleamany GM, Anding K, Avin KG, Escobar GL, Gabrys I, Goth J, Isnard M, Jhamb M, Kim JC, Wing J, Lightfoot CL, McAdams-DeMarco M, Manfredini F, Meade A, Molsted S, Parker K, Seguri-Orti E, Smith AC, Verdin N, Zheng J, Zimmerman D, Thompson S. Global Policy Barriers and Enablers to Exercise and Physical Activity in Kidney Care. Journal of Renal Nutrition [IF: 2.929] 2021. DOI: https://doi.org/10.1053/j.jrn.2021.06.007

- Krase AA, Terzis G, Giannaki CD, Stasinaki AN, Wilkinson TJ, Smith AC, Zorz C, Karatzaferi C, Stefanidid I, Sakkas GK. Seven months of aerobic intradialytic exercise training can prevent muscle loss in haemodialysis patients: an ultrasonography study. International Urology and Nephrology [IF: 1.843] 2021. DOI: https://doi.org/10.1007/s11255-021-02931-6

- Wilkinson TJ, Gabrys I, Lightfoot CL, Lambert K, Baker LA, Billany RE, Kanavaki A, Palmer J, Robinson KA, Nixon DGD, Watson EL, Smith AC. A systematic review of handgrip strength measurement in clinical and epidemiological studies of kidney disease: towards a standardized approach. Journal of Renal Nutrition [IF: 2.929] 2021. DOI: 10.1053/j.jrn.2021.06.005

- Wilkinson TJ, Gore EF, Baker LA, Watson EL, Smith AC. Muscle power and physical dysfunction: a model for tailoring rehabilitation in chronic kidney disease. Nephrology [IF: 1.749] 2021 26(10), 790-797. DOI: http://doi.org/10.1111/nep.13920

- Wilkinson TJ, Clarke AL, Nixon DGD, Hull KL, Song Y, Burton JO, Yates T, Smith AC. Prevalence and correlates of physical activity across kidney disease stages: an observational multicenter study. Nephrology Dialysis Transplantation [IF: 4.198] 2021 36(4), 641-649. DOI: https://doi.org/10.1093/ndt/gfz235 

- Wilkinson TJ, Nixon DGD, Palmer J, Lightfoot CL, Smith AC. Differences in physical symptoms between those with and without kidney disease: a comparative study across disease stages in a UK population. BMC Nephrology [IF: 2.3] 2021, 22 (147). DOI:  10.1186/s12882-021-02355-5 

- Wilkinson TJ, Miksza J, Baker LA, Lightfoot CL, Watson EL, Yates T, Smith AC. Association of sarcopenia with mortality and end-stage renal disease in those with chronic kidney disease: a UK Biobank study. Journal of Cachexia, Sarcopenia and Muscle [IF: 12.511] 2021. DOI: 10.1002/jcsm.12705

- Wilkinson TJ, Ashman J, Baker L, Watson E, Smith AC. Quantitative muscle ultrasonography using 2D textural analysis: a novel approach to assess skeletal muscle structure and quality in chronic kidney disease. Ultrasonic Imaging [IF: 1.571] 2021, 44(3). DOI: 10.1177/01617346211009788

- Lightfoot CL, Wilkinson TJ, Memory KM, Palmer JP, Smith AC. Reliability and validity of the Patient Activation Measure in CKD. Clin J Am Soc Nephrol [IF: 6.628] 2021, 16 (6) 880-888. DOI: https://doi.org/10.2215/CJN.19611220

- Wilkinson TJ, Lightfoot CJ, Memory K, Palmer J, Smith AC. Determinants of patient activation and its association with cardiovascular disease risk in chronic kidney disease: a cross-sectional study. Health Expectations [IF: 3.008] 2021, 24(3) 843-852 DOI: http://doi.org/10.1111/hex.13225

- Wilkinson TJ, Yates T, Baker LA, Zaccardi Z, Smith AC. Sarcopenic obesity and the risk of hospitalisation or death from COVID-19: findings from UK Biobank. Journal of Cachexia, Sarcopenia and Muscle Rapid Reports 2021. DOI: https://doi.org/10.1002/rco2.47

- Wilkinson TJ, Smith AC. Reply: Ad Hoc Measurements of the Anterior Thigh Muscle (Mass and Function) in Sarcopenia. Journal of Ultrasound Medicine [IF: 1.759] 2021. DOI: 10.1002/jum.15421

- Lightfoot CJ, Wilkinson TJ, Song Y, Burton JO, Smith AC. Perceptions of exercise benefits and barriers: the influence on physical activity behaviour in individuals undergoing haemodialysis and peritoneal dialysis. Journal of Nephrology [IF: 3.5] 2021. DOI: 10.1007/s40620-021-01024-y

- Watson EL, Wilkinson TJ, O’Sullivan TF, Baker LA, Gould DW, Xenophontos S, Graham-Brown M, Major R, Jenkinson C, Hewison, Phiip A, J, Smith AC. Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis. Journal of Steroid Biochemistry and Molecular Biology [IF: 3.785] 2021. DOI: 10.1016/j.jsbmb.2021.105861

- Wilkinson TJ, Smith AC. Physical activity and living well with kidney disease. Nature Reviews Nephrology [IF: 19.68] 2021. DOI: https://doi.org/10.1038/s41581-021-00398-3

2020 [10]

- Billany RE, Vadaszy N, Lightfoot CL, Graham-Brown MPM, Smith AC, Wilkinson TJ. Characteristics of effective home-based resistance training in patients with noncommunicable chronic diseases: a systematic scoping review of randomised controlled trials. Journal of Sports Sciences [IF: 2.597] 2020. DOI: 10.1080/02640414.2020.1861741

- Wilkinson TJ, Palmer J, Gore EF, Smith AC. The validity of the ‘General Practice Physical Activity Questionnaire’ against accelerometery in patients with chronic kidney disease: a validation study. Physiotherapy Theory and Practice [IF: 1.624] 2020. DOI: 10.1080/09593985.2020.1855684

- Nixon AC, Wilkinson TJ, Young HL, Taal MW, Pendleton N, Mitra S, Brady ME, Dhaygude AP, Smith AC. Symptom-burden in people living with frailty and chronic kidney disease. BMC Nephrology [IF: 1.43] 2020; 21 (411). DOI: 10.1186/s12882-020-02063-6 

- Wilkinson TJ, Gore EF, Vadaszy N, Nixon DGD, Watson EL, Smith AC. The utility of ultrasound as a valid and accurate diagnostic tool for sarcopenia: sex-specific cut-off values in chronic kidney disease. Journal of Ultrasound Medicine [IF: 1.759] 2020. DOI: 10.1002/jum.15421

- Watson EL, Major RW, Wilkinson TJ, Greening NJ, Gould DW, Barratt J, Smith AC. The association of muscle size, strength, and exercise capacity with all-cause mortality in non-dialysis dependent CKD patients. Clinical Physiology and Functional Imaging 2020. DOI: 10.1111/cpf.12655

- Wilkinson TJ, McAdams-Demarco M, Bennett PN, Wilund K. Advances in exercise therapy in pre-dialysis CKD, hemodialysis, peritoneal dialysis and kidney transplantation. Current Opinion in Nephrology and Hypertension [IF: 2.539] 2020. DOI: doi: 10.1097/MNH.0000000000000627

*Invited review

- Wilkinson TJ, Watson EL, Vadaszy N, Baker LA, Viana JL, Smith AC. Response of the oxygen uptake efficiency slope to exercise training in patients with chronic kidney disease. Kidney Research and Clinical Practice 2020. DOI: http://www.krcp-ksn.org/journal/view.html?uid=3841&vmd=Full

- Castle EM, Wilkinson TJ, Antcliffe L, Young HML. Renal rehabilitation services within the United Kingdom: protocol for a British Renal Society Rehabilitation Network survey of current practice and perspectives. Journal of Kidney Care June 2020. DOI: doi.org/10.12968/jokc.2020.5.3.120 

- Watson EL, Baker LA, Wilkinson TJ, Gould DW, Graham‐Brown MP, Major RW, Ashford RU, Philp A, Smith AC. Reductions in skeletal muscle mitochondrial mass are not restored following exercise training in patients with chronic kidney disease. The FASEB Journal [IF: 5.498] 2020; 34(1): 1755-1767. DOI: https://doi.org/10.1096/fj.201901936RR 

- Highton P, White AE, Nixon DGD, Wilkinson TJ, Neale J, Martin M, Bishop N, Smith AC. The influence of acute moderate-to-high intensity aerobic exercise on markers of immune function and microparticles in renal transplant recipients. American Journal of Physiology-Renal Physiology [IF: 3.323] 2020; 318(1): 76-85. DOI: https://doi.org/10.1152/ajprenal.00332.2019 

2019 [9]

- Wilkinson TJ, Nixon DGD, Hull KL, Richler-Potts D, Neale J, Song Y, Smith AC. Identification of the most clinically useful skeletal muscle mass indices pertinent to sarcopenia and physical performance in chronic kidney disease. Nephrology [IF: 1.913] 2019. DOI: https://doi.org/10.1111/nep.13678 

- Xenophontos S, Wilkinson TJ, Gould DW, Viana JL, Watson EL, Smith AC. Peak aerobic capacity from incremental shuttle walk test in chronic kidney disease. Journal of Renal Care [IF: 1.216] 2019; 0(0):0-5. DOI: 10.1111/jorc.12293 

- Wilkinson TJ, Nixon DGD, Smith AC. Postural stability during standing and the association with physical and cognitive functioning in non-dialysis chronic kidney disease. International Urology and Nephrology [IF: 1.692] 2019; 51:1407-1414 DOI: 10.1007/s11255-019-02192-4 

- Gould DW, Watson EL, Wilkinson TJ, Wormleighton J, Xenophontos S, Smith AC. Ultrasound assessment of muscle mass in response to exercise training in chronic kidney disease: a comparison with MRI. Journal of Cachexia, Sarcopenia and Muscle [IF: 12.511] 2019; 10: 748–755. DOI: 10.1002/jcsm.12429 

- Wilkinson T, Billany R, Lightfoot CJ, Graham-Brown M, Smith AC. 2019. Characteristics of effective home-based resistance training exercise in patients with chronic disease: a scoping review protocol. PeerJ Preprints 7:e27679v1 https://doi.org/10.7287/peerj.preprints.27679v1

- Wilkinson TJ, White EM, Nixon DGD, Gould DW, Watson EL, Smith AC. Near-infrared spectroscopy measured skeletal muscle haemoglobin oxygen saturation kinetics and exercise performance in chronic kidney disease. Clinical and Experimental Nephrology [IF: 2.100] 2019; 23(1), 32-42. DOI:  10.1007/s10157-018-1612-0 

- Wilkinson TJ, Richler-Potts D, Nixon DGD, Neale J, Smith AC. Anthropometry‐based equations to estimate body composition: a suitable alternative in renal transplant recipients and patients with non-dialysis dependent kidney disease? Journal of Renal Nutrition [IF: 2.318] 2019; 29(1), 16-23. DOI: https://doi.org/10.1053/j.jrn.2018.04.003 

- Wilkinson TJ, Xenophontos S, Gould DW, Vogt BP, Viana JL, Smith AC, Watson EL. Test-retest reliability, validation, and ‘minimal detectable change’ scores for the incremental shuttle walk test, sit-to-stand chair test, maximum leg extension strength, and cardiopulmonary exercise testing in patients with pre-dialysis chronic kidney disease. Physiotherapy Theory and Practice 2019; 35(6): 565-576. DOI: 10.1080/09593985.2018.1455249 

- Wilkinson TJ, Watson EL, Gould DW, Xenophontos S, Clarke AL, Vogt BP, Viana JL, Smith AC. 12-weeks supervised exercise improves self-reported symptom burden and fatigue in chronic kidney disease; a secondary analysis of the 'ExTra CKD' trial. Clinical Kidney Journal 2019; 12(1), 113-121. DOI: 10.1093/ckj/sfy071

*Selected by CKJ as ‘Highest Altmetric scoring articles’ in 2018 

2018 [7]

- Wilkinson TJ, Watson EL, Xenophontos S, Gould DW, Smith AC. The ‘minimum clinically important difference’ in frequently reported objective physical function tests following a 12-week renal rehabilitation exercise intervention in non-dialysis chronic kidney disease. American Journal of Physical Medicine & Rehabilitation [IF: 1.843] 2018. DOI: 10.1097/PHM.0000000000001080 

*Selected as monthly article providing CME credit to readers 
*Winner of Association of Academic Physiatrists Excellence in Research Writing Award

- MacKinnon HJ, Wilkinson TJ, Clarke AL, Gould DW, O’Sullivan TFO, Xenophontos S, Watson EL, Singh SJ, Smith AC. The association of physical function and physical activity with all-cause mortality and adverse clinical outcomes in non-dialysis chronic kidney disease: a systematic review. Therapeutic Advances in Chronic Disease [IF: 4.900] 2018; 9(11): 209–226. DOI: 10.1177/2040622318785575 

- Wilkinson TJ, Gould DW, Nixon DGD, Watson EL, Smith AC. Quality over quantity? Effects of skeletal muscle myosteatosis and fibrosis on physical functioning in chronic kidney disease. Nephrology Dialysis and Transplantation [IF 4.085] 2018; gfy139: 1-18. DOI: 10.1093/ndt/gfy139 

- Lemmey AB, Wilkinson TJ, Perkins CM, Nixon LA, Sheikh F, Jones JG, Ahmad YA, O’Brien TD. Muscle Loss Following a Single High-Dose Intramuscular Injection of Corticosteroids to Treat Disease Flare in Rheumatoid Arthritis Patients. European Journal of Rheumatology 2018 5(3), 160-164. DOI: 10.5152/eurjrheum.2018.17148 

- Watson EL, Gould DW, Wilkinson TJ, Xenophontos S, Clarke AL, Vogt BP, Viana JL, Smith AC. 12 weeks combined resistance and aerobic training confers greater benefits than aerobic alone in non-dialysis CKD. American Journal of Physiology-Renal Physiology [IF: 3.611] 2018 316(6), 1188-1196. DOI: 10.1152/ajprenal.00012.2018. 

- Wilkinson TJ, Lemmey AB, Clayton RJ, Jones JG, O’Brien TD. The ‘8-foot up and go’ test is the best way to assess physical function in the rheumatoid arthritis clinic. Rheumatology Advances in Practice [Rheumatology] 2018; rkx017. DOI: doi.org/10.1093/rap/rkx017 

2017 [3]

- Wilkinson TJ. Spinning exercise-induced rhabdomyolysis and AKI. Journal of Kidney Care 2017; 2(5): 245.

*Invited editorial

- Highton P, Neale J, Wilkinson TJ, Bishop L, Smith AC. Physical Activity, Immune Function and Inflammation in Kidney Patients: the PINK Study Protocol. British Medical Journal (BMJ) Open [IF 2.271] 2017; 7(5) e014713. DOI: 10.1136/bmjopen-2016-014713 

- Wilkinson TJ, Gould DW, Watson EL, Smith AC. Commentary: Renal function estimation and Cockcroft–Gault formulas for predicting cardiovascular mortality in population based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. Frontiers in Medicine Nephrology 2017. DOI: 10.3389/fmed.2017.00077 

- 2016 [3]

- Lemmey AB, Wilkinson TJ, O’Brien TD, Clayton RJ, Whale JL, Jones HSJ, Ahmad Y, Chitale S, Sheikh F, Jones JG, Maddison PJ. Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients. Rheumatology [IF 4.435] 2016; 55(10):1736-45. DOI: 10.1093/rheumatology/kew243. 

*Selected for feature in Atlas of Science November 2016.

- Wilkinson TJ, Shur NF, Smith AC. "Exercise as medicine" in chronic kidney disease. Scandinavian Journal of Medicine & Science in Sports [IF 3.025] 2016; 28(8): 985-988. DOI: 10.1111/sms.12714. 

- Wilkinson TJ, Lemmey AB, Ahmad Y, Chitale S, Sheikh F, Jones JG, Maddison PJ, O’Brien TD. Can creatine supplementation improve body composition and objective physical function in rheumatoid arthritis patients? A randomised control trial. Arthritis Care & Research [IF 4.039] 2016; 68(6): 729-737. DOI: 10.1002/acr.22747.

*Selected for feature in World Biomedical Frontiers Arthritis edition 2016 for outstanding quality and impact.

2015 [2]

- Wilkinson TJ. Commentary: Rheumatoid cachexia revisited: a metabolic co-morbidity in rheumatoid arthritis. Frontiers in Nutrition 2015; 2(37). DOI: 10.3389/fnut.2015.00037. 

- Wilkinson TJ, Lemmey AB, O'Brien TD, Ahmad Y, Chitale S, Sheikh F, Jones J. Significant muscle loss following intramuscular corticosteroid injection used to treat active rheumatoid arthritis; a case report. Journal of Rheumatology & Orthopedics 2015; 2(2). DOI: 10.7243/2055-7000-2-2. 

2014 [1]

- Wilkinson TJ, O’Brien TD, Lemmey AB. Oral creatine supplementation: A potential adjunct therapy for rheumatoid arthritis patients. World Journal of Rheumatology 2014; 4(3): 22-34. DOI: 10.5499/WJR.v4.i3.22

I currently supervise three PhD students and have supervised several BSc. and MSc. students to completion. I am willing to supervise prospective students with an interest in multimorbidity chronic disease lifestyle exercise and physical activity sarcopenia and frailty.

Current PhD students:

- Ashkon Ardavani, University of Leicester, PhD, 2021 – Present. Primary supervisor with Dr Ffion Curtis and Prof Kamlesh Khunti (‘Risk factor prevention for developing CKD in multi-ethnic groups living with multimorbidity’)
- Matt Lee, University of Leicester, PhD, 2021 – Present. Co-supervisor with Dr Seth O’Neil (‘The Impact of Achilles Tendinopathy and the relevance of Ultrasound Tissue Characteristics to the Elite Rugby Player’)
- Noemi Vadaszy, University of Leicester, PhD, 2019 - Present. Co-supervisor with Prof. AC Smith (‘Home-based exercise in CKD’)

Guest lecturer on the MSc. ‘Chronic Disease & Immunity’ course at the University of Leicester.

I am happy to be contacted to discuss work around my research interests e.g. multimorbidity chronic disease lifestyle exercise and physical activity sarcopenia and frailty

• Global Renal Exercise Group Organising Committee Member (Scientific Director)
• Society of Cachexia Sarcopenia and Wasting Disorders (Associate member #10750) UKKA (Scientist)
• British Renal Society Rehabilitation Network
• Kidney Research UK
• East Midlands Research into Ageing Network UK
• KRUK ‘Exercise and Lifestyle’ CSG
• Kidney Beam Working Group
• Midlands Sarcopenia Working Group Living Well with Kidney Disease
• SIG NIHR DART Diet and Physical Activity Assessment Toolkit Working Group

External grant reviewer: Kidney Research UK; FIN-RER- Health Research Programme of the Emilia-Romagna Bottom-up Projects-Call Abstract reviewer: UK Kidney Week conference Session chairs: UK Kidney Week

• University of Leicester Merit Award 2020 for outstanding excellence and achievement in the previous year.
• Association of Academic Physiatrists Excellence in Research Writing Award 2019 for article on “The ‘minimum clinically important difference’ in frequently reported objective physical function tests following a 12-week renal rehabilitation exercise intervention in non-dialysis chronic kidney disease.”
• Lockwood Award 2017 Renal Association 2017. For significant contribution to renal medicine research
• Travel Grant European Renal Association- European Dialysis Transplant Association Congress 2017 Madrid. Awarded as shortlisted for one of the “best abstracts presented by young authors”. 

Television: Notts TV

Podcasts: Keep It Renal (discussion around transplant research and self-management research with Katherine Memory (student) and Dr Carl May Bristol UK)

Print: Leicester Mercury

Radio: BBC Radio Leicester

Online: Various including Renal and Urology News, BBC News, Daily Mail, Health Europa, Nursing Times, News-Medical.net.

• Ph.D Clinical Exercise and Health Physiology
• Postgraduate Certificate in Higher Education (PGCHE) Associate Fellow of the Higher Education Academy’
• B.Sc. (with Honours) Sport and Exercise Science