Research groups

Metalloenzyme mechanism with sub-turnover frequency time resolution

Structure-based drug discovery

Structural architecture of DNA repair machinery

Structure and function of RNA processing complexes

Stabilising Protein-Protein interactions

RNA Splicing: from single-molecules to therapy

Regulation and molecular architecture of apoptotic protein complexes

Conformational mechanisms of lung and liver disease

Synthetic organic chemistry and chemical biology

Understanding the functional role of Formaldehyde in health and disease

Biospectroscopy and imaging

Metalloenzyme mechanisms

Enzyme structure and function

Molecular mechanisms of sensory perception and metabolic regulation in bacteria

Structural biology of signal transduction and epigenetic gene regulation

Single molecule dynamics of gene expression

Chromatin structure and function

Molecular modelling and bioinformatics

Structural biology of transcriptional repression complexes

Metallopharmaceuticals for the treatment of cancer

Structural biology of Ca2+-transport regulation complexes

Structural biology of complement activation