Alharbi, A., Thompson, J. P., Brindle, N. P. & Stover, C. M (2019) “Ex vivo modelling of the formation of inflammatory platelet-leucocyte aggregates and their adhesion on endothelial cells, an early event in sepsis” Clin. Exp. Med. 19, 321-337.
Issa, E, Moss, AJ, Fischer, M, Kang, M, Ahmed, S, Farah, H, Bate, N, Giakomidi, D & Brindle NPJ (2018) “Development of an orthogonal Tie2 ligand resistant to inhibition by Ang2” Molecular Pharmaceutics 15, 3962-3968.
Alawo, DOA, Tahir, TA, Fischer,M, Bates, D, Amirova, SR & Brindle, NPJ (2017). "Regulation of Angiopoietin Signalling by Soluble Tie2 Ectodomain and Engineered Ligand Trap." Sci Reports 7(1): 3658.
Fischer, M., M. Kang and N. P. Brindle (2016). "Using experimental evolution to probe molecular mechanisms of protein function." Protein Sci 25(2): 352-359.
Tahir, TA, Singh, H & Brindle NPJ. The RNA binding protein hnRNP-K mediates post –transcriptional regulation of Uncoupling Protein-2 by angiopoietin-1. Cell Signal (2014) 26 1379-1384.
Brindle, NP, Sale, JE, Arakawa, H, Buerstedde, JM, Nuamchit, T, Sharma, S, Steele, KH. Directed evolution of an Angiopoietin-2 ligand trap by somatic hypermutation and cell surface display. J Biol Chem (2013) 288, 33205-33212.
Singh H, Hansen TM, Patel N, Brindle NPJ. The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling. PLoS ONE (2012) 7(1): e29319.
Singh, H, Tahir, TA, Alawo, DOA, Issa, E & Brindle NPJ. Molecular control of angiopoietin signaling. Biochem Soc Trans (2011) 39 1592-1596.
Hansen, TM, Singh, H, Tahir, TA & Brindle NPJ (2010) “Effects of Angiopoietin-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface” Cellular Signalling 22 527-532.
Kopp, PM, Bate, N, Hansen, TM, Brindle, NP, Praekelt, U, Debrand, E, Coleman, S, Mazzeo, D, Goult, BT, Gingras, AR, Pritchard, CA, Critchley, DR, Monkley, SJ (2010) “Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1” European Journal of Cell Biology 89 661-673.