Dr Ralf Schmid
Associate Professor in Bioinformatics
School/Department: Molecular Cell Biology, Department of
Email: rs206@leicester.ac.uk
Profile
Research
Publications
(0) Discovery and structure relationships of salicylanilide derivatives as potent, non-acidic P2X1 receptor antagonists
M Tian, A Abdelrahman, Y Baqi, E Fuentes, D Azazna, C Spanier, S Densborn, S Hinz, R Schmid, CE Müller (2020)
Journal of medicinal chemistry 63 (11), 6164-6178
Mapping the site of action of human P2X7 receptor antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the intersubunit allosteric pocket
AB Dayel, RJ Evans, R Schmid (2019)
Molecular pharmacology 96 (3), 355-363
ATP-gated P2X receptor channels: molecular insights into functional roles
R Schmid, RJ Evans (2019)
Annual review of physiology 81, 43-62
A mechanism for CO regulation of ion channels
SM Kapetanaki, MJ Burton, J Basran, C Uragami, PCE Moody, JS Mitcheson, R Schmid, NW Davies, P Dorlet, MH Vos, NM Storey, E Raven (2018)
Nature communications 9 (1), 1-10
Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120
RC Allsopp, S Dayl, R Schmid, RJ Evans (2017)
Scientific reports 7 (1), 1-12 35
A heme-binding domain controls regulation of ATP-dependent potassium channels
MJ Burton, SM Kapetanaki, T Chernova, AG Jamieson, P Dorlet, J Santolini, PCE Moody, JS Mitcheson, NW Davies, R Schmid, EL Raven, NM Storey (2016)
Proceedings of the National Academy of Sciences 113 (14), 3785-3790
The splicing landscape is globally reprogrammed during male meiosis
R Schmid, SN Grellscheid, I Ehrmann, C Dalgliesh, M Danilenko, MP Paronetto, S Pedrotti, D Grellscheid, RJ Dixon, C Sette, IC Eperon, DJ Elliott (2013)
Nucleic acids research 41 (22), 10170-10184
Fascaplysin as a specific inhibitor for CDK4: Insights from molecular modelling
MI Shafiq, T Steinbrecher, R Schmid (2012)
Public Library of Science 7 (8), e42612
Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel
JA Roberts, RC Allsopp, S El Ajouz, C Vial, R Schmid, MT Young, RJ Evans (2012)
Proceedings of the National Academy of Sciences 109 (12), 4663-4667
Cytosolic metal handling in plants: determinants for zinc specificity in metal transporters and metallothioneins
CA Blindauer, R Schmid (2010)
Metallomics 2 (8), 510-529
annot8r: GO, EC and KEGG annotation of EST datasets
R Schmid, ML Blaxter (2008)
BMC bioinformatics 9 (1), 1-6
A transcriptomic analysis of the phylum Nematoda
J Parkinson, M Mitreva, C Whitton, M Thomson, J Daub, J Martin, R Schmid, N Hall, B Barrell, RH Waterston, JP McCarter, ML Blaxter (2004)
Nature genetics 36 (12), 1259-1267
PartiGene—constructing partial genomes
J Parkinson, A Anthony, J Wasmuth, R Schmid, A Hedley, M Blaxter (2004)
Bioinformatics 20 (9), 1398-1404
Supervision
Teaching
Undergraduate Teaching:
BS2040 Bioinformatics, BS2093 Protein Control in Cellular Regulation, BS3070 Structural Biology
Postgraduate Teaching (MSc in Bioinformatics):
BS7102 Proteins: Structure and Bioinformatics, BS7105 Bioinformatics Programming and Advanced Topics in Bioinformatics, BS7120 Steered Research Project
Press and media
Qualifications
Diplom Chemiker (sehr gut) Albert-Ludwigs-Universität Freiburg
Dr. rer. nat. (summa cum laude) Albert-Ludwigs-Universität Freiburg
FHEA