Example MD projects

Self-funding students or students seeking MD studentship opportunities are encouraged to view the example projects offered below by supervisors in our department. If you are interested, please contact the relevant supervisor for each project.

In the case of supervisors or co-supervisors who work in other departments, their main department is denoted in parentheses following their name.

Title	Supervisor	Co-supervisor
The novel application of clinical optical coherence tomography and pressure wire assessment to post-mortem computed tomography angiography	Dr David Adlam	Professor Bruno Morgan (Leicester Cancer Research Centre)
Cardiologists' knowledge, attitudes and application of risk towards Implantable Cardioverter Defibrillators	Dr T R Betts	Professor G André Ng
Plasma matrix metalloproteinase as predictors of prognosis in acute decompensated heart failure	Professor Leong Loke Ng	Professor Alison H Goodall
Biomarkers in diastolic heart failure	Professor Leong Loke Ng	Professor Iain B Squire
What is the incidence, mechanism and optimal management of severe hypertension after carotid endarterectomy?	Professor A Ross Naylor	Professor Iain B Squire
Predictors of functional recovery and left ventricular remodelling following acute myocardial infarction	Professor Iain B Squire	Professor Matt Bown
The significance of glucose transporters in the abdominal aortic aneurysm pathogenesis	Professor Matt Bown	Professor Rob Sayers
An investigation into microRNA expression profiles in abdominal aortic aneurysm disease	Professor Matt Bown	Professor Rob Sayers
An investigation into genetic polymorphisms and abdominal aortic aneurysms	Professor Matt Bown	Dr P Stafford/Dr Fernando Soares Schlindwein (Department of Engineering)
An investigation into gene expression profiles in abdominal aortic aneurysms	Professor Rob Sayers	Professor Matt Bown
STARTREC – Simplifying technologies for peripheral arterial disease recognition	Professor Rob Sayers	Professor Matt Bown
The natural history of type II endoleaks after endovascular abdominal aortic aneurysm repair	Professor Rob Sayers	Professor David G Lambert
The In Vitro Effects of Antiangiogenic Treatment on Abdominal Aortic Aneurysms	Mr E Choke	Professor Rob Sayers
Investigating the analgesic effects of intrathecal Nociceptin (N/OFQ)	Professor Jonathan P Thompson	Professor David G Lambert
The role of the endogenous nociceptin system in modulating the inflammatory processes of sepsis and the systemic inflammatory response syndrome	Professor Jonathan P Thompson	Professor Gerry McCann
Complete versus lesion-only Primary PCI pilot - Cardiac MRI substudy	Professor Gerry McCann	Professor Tony Gershlick
Endothelial homeostasis as a therapeutic modality in post-cardiac surgery inflammatory organ injury	Professor Gavin J Murphy	Professor Gerry McCann
Exploring possible causes for coronary stent thrombosis	Professor Tony Gershlick	Professor Alison H Goodall
Intracoronary Adenosine Versus Sodium Nitroprusside and Control for Attenuation of Microvascular Obstruction during Primary PCI	Professor Tony Gershlick	Dr Amit Mistri
Blood Pressure Variability and Stroke	Professor Jonathan P Thompson	Dr Frank Proudlock (Psychology and Vision Sciences)
The epidemiology of major trauma: The analysis of a multiagency injury research register implications for better prevention and treatment	Dr R Mackenzie	Professor Timothy J Coats
Investigating persistent atrial fibrillation using non-contact array and body surface potential mapping	Professor G André Ng	Dr P Stafford/Dr A Sandilands
ULTIMATE: Using Lifemap to Investigate Malignant Arrhythmia Therapy	Professor G André Ng	Dr Will Nicolson
Role of signal averaged P waves in predicting recurrence of AF after pulmonary vein isolation	Professor G André Ng	Dr P Stafford/Dr A Sandilands
Engineering of novel angiopoietin 2 trap	Professor Nick Brindle	Dr Peter Moody (Department of Molecular and Cell Biology)
Dissecting cell signalling pathways by incorporation of unnatural amino acids for synthetic biology	Professor Nick Brindle	Dr Ralf Schmid (Department of Molecular and Cell Biology)