Wellcome Trust Projects 2023
Projects in Theme 1 (Genomics for Drug Development and Pharmacogenetics)
- Multi-omic approaches to understand the medium and long-term effects of COVID-19 and identify novel therapeutic opportunities (T1/46)
- Exploring the contribution of complex genomic variation to fibrosis risk (T1/51)
- The role of rare genetic variants in progressive pulmonary fibrosis (T1/53)
- Applying machine learning to find clinical and genetic predictors for radiotherapy side effects (T1/54)
- Genetic epidemiology of chronic cough (T1/57)
- Phenome wide association studies of the human leukocyte antigen region (T1/62)
Projects in Theme 2 (Genomics for Precision Medicine in Underserved Populations)
Three projects listed under Cross-Theme projects below.
Projects in Theme 3 (Genetically Informed Causal Inference and Risk Prediction)
- Providing up-to-date risk estimates from prognostic models: further development and application of temporal recalibration (T3/48)
- Social inequality in child mental health difficulties – understanding epigenetic and family pathways (T3/49)
- Achilles tendon disorders – How much of it is your Genes? (T3/59)
Projects in Theme 4 (Ethical, Legal and Social Implications of Genomics and Genomic Epidemiology Studies)
- Maternal and paternal futures: responsibilisation practices in the preconception period to ensure health outcomes for babies (T4/44)
- Examining the legal, ethical and social implications of whole genome sequencing at birth (T4/50)
- Developing a framework to increase diversity in genomic studies (T4/52)
- Combining insights and analytical approaches from genomics and sociology to explore trajectories of substance use by young people. (T4/61)
Cross-Theme Projects
- Mucin genetic variation in lung disease (T12/55)
- Understanding asthma through population-scale long-read sequencing of diverse genomes (T12/56)
- Applying multi-omics to understand the functional role genetic variants play in the biology of lung function and COPD (T13/60)
- Why are men and women so different? – Investigating sex-specific genomic-risk and telomere length (T23/45)