Research opportunities
Funding
The Institute for Precision Health offers numerous funding opportunities to enhance your research and industrial collaborations via the UKRI MRC Impact Acceleration Accounts (IAA) award. Funding calls will be announced via the Institute and drugdiscovery@le.ac.uk mailbox at several points during the year. There may be further opportunity for small awards in between formal calls, so please email drugdiscovery@le.ac.uk to talk through your ideas.
Additionally, the Institute can provide funding to facilitate networking opportunities for grant development. Please contact Lynne Howells (lh28@le.ac.uk) for further information.
Postgraduate research
The Institute for Precision Health has an active postgraduate community. New studentships will be announced here, and we welcome enquiries about our PhD projects.
Our new PhD studentship opportunities
- Developing a translational clinical interface for using RNA sequencing data in the evaluation of prospective tuberculosis (TB) risk
- Inequalities in precision medicine in under-served groups
- Circulating RNA as a liquid biopsy for cancer detection and tissue-of-origin prediction
- Predicting circulatory mortality and morbidity using deep learning and retinal imaging
Our new students are undertaking world-leading research in the following areas:
Functional investigation of a potential novel drug target for progressive lung fibrosis
- Catherine McMullen, supervised by Dr Katy Roach and Professor Louise Wain
Developing a virtual asthma patient
- Mahesh Ola, supervised by Dr Himanshu Kaul and Professor Chris Brightling
Investigation of proteomic biomarkers of hypertension using microsampling-based mass spectrometry detection
- Elliott Gyedu, supervised by Dr Pankaj Gupta and Dr Dennis Bernieh
Radiomic and multiomic investigation of molecular pathways in concentric left ventricular myocardial remodelling in Type 2 Diabetes (T2DM)
- Nikita Bhakta, supervised by Professor Leong Ng and Dr Alastair Moss
Mechanisms of intrinsic resistance to bispecific antibodies in diffuse large B cell lymphoma (DLBCL)
- Joshua Bray, supervised by Dr Harriet Walter and Professor Martin Dyer
Understanding the effect of SGLT2i on muscle health in those with chronic disease
- Cian Sutcliffe, supervised by Professor Melanie Davies and Dr Luke Baker
Further postgraduate research
2021
Targeting Mutant FBXW7 to Disable MCL1 and Induce Therapeutic Apoptosis
- Daniel Rowell Faulkner, supervised by Professor Dean Fennell
Novel therapeutic and diagnostic approaches for EML4-ALK driven lung cancer
- Savvas Papageorgiou, supervised by Professor Andrew Fry
2020
microRNAs and fibrosis progression in asymptomatic Aortic Stenosis: towards an integrated imaging and biomarker precision medicine approach to risk stratification
- Osekafore Adewuyi, supervised by Dr Anvesha Singh
Identifying mechanisms of drug resistance in endometrial cancer
- Gemma Donaldson, supervised by Professor Catrin Pritchard
2019
Using patient electronic health records to understand the interplay between disease severity, symptoms, co-morbidity and long-term health outcomes
- Urvee Karsanji, supervised by Professor Mick Steiner
Prediction of outcome in community acquired pneumonia admissions using Artificial Intelligence and machine learning based algorithms
- Daniel Lozano Rojas, supervised by Dr Rob Free
The relationship between repetitive DNA and clinical radioresponse in rectal cancer
- Leanne Herbert, supervised by Dr Cristina Tufarelli
Barriers to CD19 therapy in B cell malignancies
- Gethin Thomas, supervised by Dr Harriet Walter
Developing a new bioinformatics platform for integration and analysis of high throughput ‘omics data to inform drug discovery and precision medicine approaches
- Emma Croot, supervised by Dr Athanasios Didangelos