Institute for Precision Health

Research opportunities

Funding

The Institute for Precision Health offers numerous funding opportunities to enhance your research and industrial collaborations via the UKRI MRC Impact Acceleration Accounts (IAA) award. Funding calls will be announced via the Institute and drugdiscovery@le.ac.uk mailbox at several points during the year. There may be further opportunity for small awards in between formal calls, so please email drugdiscovery@le.ac.uk to talk through your ideas.

Additionally, the Institute can provide funding to facilitate networking opportunities for grant development. Please contact Lynne Howells (lh28@le.ac.uk) for further information.

Internship - expression of interest from investigators

The Institute for Precision Health is pleased to announce that they will fund, over Summer 2024, one 4-week health-related research internship for a 2nd year undergraduate student as part of the Institute’s widening participation strategy.
This scholarship, which will offer a valuable training opportunity, is open to 2nd year undergraduate home students belonging to any school within the University of Leicester (only UoL students will be considered).

This internship should preferably run between the 10th June and 19th July (allowing final Unitemps payments to be made prior to end of financial year).

The successful candidate will receive a stipend at the real living wage rate (currently £12/hr) for a period of 4 weeks. The internship will be supported by up to £250 towards project costs.

We are now calling for an expression of interest from investigators. If you are able to host a student over the summer for a 4 week health-related project, please could you provide:

  • Name and Department
  • Prospective project title with brief project overview
  • Skills the student would gain from the project.

Please send the above details to Lynne Howells lh28@leicester.ac.uk by 8 December.
Projects will be advertised to students in the New Year, interviews conducted in the 1st week of March, and outcomes communicated to all applicants by the week commencing 11/03/24.

Postgraduate research

The Institute for Precision Health has an active postgraduate community. New studentships will be announced here, and we welcome enquiries about our PhD projects. 

Our students are undertaking world-leading research in the following areas:

Circulating RNA as a liquid biopsy for cancer detection and tissue-of-origin prediction

Inequalities in precision medicine in under-served groups

Proteomic investigation of markers of chronic inflammation in cardiovascular disease

Functional investigation of a potential novel drug target for progressive lung fibrosis

Developing a virtual asthma patient

Investigation of proteomic biomarkers of hypertension using microsampling-based mass spectrometry detection

  • Elliott Gyedu, supervised by Dr Pankaj Gupta and Dr Dennis Bernieh

Radiomic and multiomic investigation of molecular pathways in concentric left ventricular myocardial remodelling in Type 2 Diabetes (T2DM)

Mechanisms of intrinsic resistance to bispecific antibodies in diffuse large B cell lymphoma (DLBCL)

Understanding the effect of SGLT2i on muscle health in those with chronic disease

Further research

2021

Targeting Mutant FBXW7 to Disable MCL1 and Induce Therapeutic Apoptosis

  • Daniel Rowell Faulkner, supervised by Professor Dean Fennell

Novel therapeutic and diagnostic approaches for EML4-ALK driven lung cancer

2020

microRNAs and fibrosis progression in asymptomatic Aortic Stenosis: towards an integrated imaging and biomarker precision medicine approach to risk stratification

Identifying mechanisms of drug resistance in endometrial cancer

2019

Using patient electronic health records to understand the interplay between disease severity, symptoms, co-morbidity and long-term health outcomes

Prediction of outcome in community acquired pneumonia admissions using Artificial Intelligence and machine learning based algorithms

  • Daniel Lozano Rojas, supervised by Dr Rob Free

The relationship between repetitive DNA and clinical radioresponse in rectal cancer

Barriers to CD19 therapy in B cell malignancies

Developing a new bioinformatics platform for integration and analysis of high throughput ‘omics data to inform drug discovery and precision medicine approaches

  • Emma Croot, supervised by Dr Athanasios Didangelos

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