People
Dr Cristina Tufarelli
Wellcome Trust Research Career Re-entry Fellow
School/Department: Genetics and Genome Biology, Department of
Telephone: +44 (0)116 223 1853
Email: ct296@leicester.ac.uk
Profile
Research
Publications
1. Ahmad A, Strohbuecker S, Scotti C, Tufarelli C, Sottile V. In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif. Cells. 2020 Nov 13;9(11):2471.
2. Karwad MA, Couch DG, Wright KL, Tufarelli C, Larvin M, Lund J, O'Sullivan SE. Endocannabinoids and Endocannabinoid-Like Compounds Modulate Hypoxia-Induced Permeability in CaCo-2 Cells via CB 1, TRPV1, and PPARα. Biochem Pharmacol 2019 Oct;168:465-472
3. Al-Khyatt W, Tufarelli C, Khan R, Iftikhar SY. Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro. BMC Cancer 2018 Feb 1;18(1):121
4. Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M, Graham B, Smith AJH, Lund JN, Hughes J, Higgs DR, Tufarelli C. DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7526-E7535
5. Ahmad A, Strohbuecker S, Tufarelli C*, Sottile V*. SOX1-OT and its link to SOX1 gene expression in neural differentiation and cancer. Cell Mol Life Sci. 2017 Oct 17; 74(22):4245-4258 - *corresponding authors
6. Vafadar-Isfahani N, Parr C, McMillan LE, Sanner J, Yeo Z, Saddington S, Peacock O, Cruickshanks HA, Meehan RR, Lund JN, & Tufarelli C. Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer. Epigenetics. 2017 Jun 3;12(6):465-475
7. Xu, H., Aboobaker, A., Emes, R., Lund, J. & Tufarelli, C. TECDetec: Transposable element chimeric transcripts detector, <https://github.com/gooday23/TECDetec> (2014).
8. Peacock O, Lee AC, Cameron F, Tarbox R, Vafadar-Isfahani N, Tufarelli C*, Lund JN. Inflammation and MiR-21 pathways functionally interact to downregulate PDCD4 in colorectal cancer. PLoS One. 2014 Oct 13;9(10):e110267 - *corresponding author
9. Cruickshanks HA, Vafadar-Isfahani N, Dunican DS, Lee A, Sproul D, Lund JN, Meehan RR, Tufarelli C. Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer. Nucleic Acids Res. 2013 Aug 1;41(14):6857-6869
10. Armstrong CA, Jones GD, Anderson R, Iyer P, Narayanan D, Sandhu J, Singh R, Talbot CJ, Tufarelli C. DNMTs are required for delayed genome instability caused by radiation. Epigenetics. 2012 Aug;7(8):892-902