Cancer cells promote cell division errors

Kellie Lucken - PhD Student

In this image we see three cells about to divide.

The cell in the centre of the image has normal bipolar morphology and will divide successfully into two daughter cells without any errors. The other two cells about to divide have duplicated their centrosomes (in green) and have tried to cluster these into a pseudo-bipolar state.

This arrangement has detrimental implications for chromosome biorientation promoting chromosomal segregation errors and cancer progression through accumulated genetic mutations.