People

Directors

Professor Don Jones

• Professor in Translational Biomarkers
• Head of Division of Cancer Sciences
• Research in application of Mass Spectrometry in Biomarker discovery through to clinical implementation

Professor Jones' Profile

Professor Leong L Ng

• Professor of Medicine and Therapeutics
• Consultant Physician
• Research in Biomarkers of Heart Failure including NT-ProBNP, PENK and second generation risk markers

Professor Ng's Profile

Dr Pankaj Gupta

• Consultant Chemical Pathologist and Metabolic Physician
• Co-Director National Centre for Adherence Testing (NCAT)
• Vice-Chair, Working Group on Cardiovascular Pharmacotherapy and Adherence. European Society of Hypertension
• Translational Research in drug adherence particularly around hypertension drugs

Professor Toru Suzuki

• Professor of Cardiovascular Medicine
• Leicester PI for the UK Consortium on MetAbolic Phenotyping (MAPUK)
• Research in Aortic Disease and novel CVD markers from the Gut/Heart axis including TMAO
• Co-lead of LeDucq Network of Excellence

Professor Suzuki's Profile

Post-Doctoral Staff

Dr Dennis Bernieh

• Research Fellow
• Proteomics, Metabolomics, Microsampling, Biomarker discovery/validation
• Involves the application of mass spectrometry-based omics approaches to understand how fundamental metabolic processes are altered in multimorbid cardiovascular disease

Dr Bernieh's ORCID profile

Dr Thong Huy Cao (MD, MSc Med, PhD)

• Research Associate (funded by the NIHR Leicester Biomedical Research Centre)
• Clinician–scientist with experience in cardiology, cardiovascular research, and student supervision in clinical and translational science, as well as experience in teaching and clinical instruction for medical students
• Heart failure (HFrEF, HFpEF, HFimpEF), mass spectrometry-based multi-omics (proteomics, metabolomics, lipidomics), biomarker discovery for risk stratification, prognosis, and precision medicine and identification of novel therapeutic targets

Dr Cao's ORCID profile Dr Cao's Profile

Dr Dan Lane

• Post-Doctoral Research Associate (funded by the NIHR Leicester Biomedical Research Centre)
• Method development, validation, and clinical translation for mass spectrometry tests for both small molecule (adherence testing/therapeutic drug monitoring) and bottom-up proteomics (hypertension). Biomarker discovery for cardiometabolic diseases. Development of software (ValidateLabs™) for validation data processing
• Automation and development of rapid multiplexed assays for clinical use and commercialisation

Dr Lane's ORCID profile

Dr Ellen Liggett

• Post-Doctoral Research Associate (Funded by the BHF Leicester Centre of Research Excellence)
• Structural Mass Spectrometry and Proteomics
• Cardiovascular Interventions

Dr Liggett's ORCID profile

Dr Colleen Maxwell

• Post-Doctoral Research Associate (funded by the British Heart Foundation)
• BHF project grant investigating a novel proteomic panel for the exclusion of coronary artery disease in low-risk individuals
• Particularly interested in developing high throughput, scalable bottom-up proteomics protocols and LC-MS methods that can be applied to large clinical cohorts

Dr Maxwell's ORCID profile

Dr Farah Salim

• Post-Doctoral Research Associate (funded by the NIHR Leicester Biomedical Research Centre)
• Mass spectrometry based proteomic and metabolomic research to identify and validate biomarkers of early heart failure in people with type 2 diabetes
• High-throughput proteomic and small-molecule LC-MS assay development, optimisation, and validation for application in large clinical cohorts

Dr Salim's ORCID profile

Dr Jodie Sandhu

• Post-Doctoral Research Associate (Funded by the British Heart Foundation)
• Metabolomic and Lipidomic profiling in T2D patients with asymptomatic Heart Failure
• Metabolomics, Lipidomics and targeted MS Assays in Cardiovascular Research

Dr Sandhu's ORCID profile

Dr Gez Williams

• Post-Doctoral Research Associate (Funded by the British Heart Foundation)
• BHF funded Research in asymptomatic aortic stenosis and sudden cardiac death experience in proteomics discovery and targeted as well as discovery metabolomics
• IAA-MRC funded woman’s health research project: Sex-Based Differences in Guideline-Directed Medical Therapy (GDMT) Plasma Levels

Dr Williams' ORCID profile

Technical staff

Dr Raj Singh

• Mass Spectrometry Manager
• Research interests in Biomarkers, Biomonitoring and molecular elucidation
• Experience in DNA adduct method development, drug metabolite ID and all aspects of LC-MS