Professor Toru Suzuki

Professor/Chair of Cardiovascular Medicine/Associate Dean

School/Department: Cardiovascular Sciences, Department of

Telephone: +44 (0)116 204 4741



My research interests are centred on understanding the mechanistic basis of cardiovascular diseases with a special interest in translational aspects.


Notable fields of interest include - aortic diseases, gut microbiome and heart disease, cardiovascular biomarkers/proteomics/phenomics -- Leicester PI for the UK Consortium on MetAbolic Phenotyping (MAPUK), clinical/healthcare data science


Publications (from most recent) - 
Israr MZ, Zhan H, Salzano A, Voors AA, Cleland JG, Anker SD, Metra M, van Veldhuisen DJ, Lang CC, Zannad F, Samani NJ, Ng LL, Suzuki T; BIOSTAT-CHF investigators (full author list as appendix). Surrogate markers of gut dysfunction are related to heart failure severity and outcome-from the BIOSTAT-CHF consortium. Am Heart J. 2022;248:108-119.
Israr MZ, Ibrahim W, Salzano A, Sarmad S, Wilde MJ, Cordell RL, Greening NJ, Brightling CE, Siddiqui S, Suzuki T; EMBER consortium. Association of gut-related metabolites with respiratory symptoms in COVID-19: A proof-of-concept study. Nutrition. 2022;96:111585.
Shehata E, Parker A, Suzuki T, Swann JR, Suez J, Kroon PA, Day-Walsh P. Microbiomes in physiology: insights into 21st-century global medical challenges. Exp Physiol. 2022;107:257-264.
Israr MZ, Bernieh D, Salzano A, Cassambai S, Yazaki Y, Heaney LM, Jones DJ, Ng LL, Suzuki T. Association of gut-related metabolites with outcome in acute heart failure. Am Heart J. 2021;234:71-80.
Braverman AC, Mittauer E, Harris KM, Evangelista A, Pyeritz RE, Brinster D, Conklin L, Suzuki T, Fanola C, Ouzounian M, Chen E, Myrmel T, Bekeredjian R, Hutchison S, Coselli J, Gilon D, O'Gara P, Davis M, Isselbacher E, Eagle K. Clinical Features and Outcomes of Pregnancy-Related Acute Aortic Dissection. JAMA Cardiol. 2021;6:58-66.
Israr MZ, Salzano A, Yazaki Y, Voors AA, Ouwerkerk W, Anker SD, Cleland JG, Dickstein K, Metra M, Samani NJ, Ng LL, Suzuki T; BIOSTAT-CHF consortium.  Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT-CHF. Eur J Heart Fail. 2020;22:1486-1490.
Yazaki Y, Aizawa K, Israr MZ, Negishi K, Salzano A, Saitoh Y, Kimura N, Kono K, Heaney L, Cassambai S, Bernieh D, Lai F, Imai Y, Kario K, Nagai R, Ng LL, Suzuki T. Ethnic differences in association of outcomes with trimethylamine N-oxide in acute heart failure patients. ESC Heart Fail. 2020;7:2373-2378.
Salzano A, Israr MZ, Garcia DF, Middleton L, DAssante R, Marra AM, Arcopinto M, Yazaki Y, Bernieh D, Cassambai S, Page K, Rengo G, Bossone E, Cittadini A, Shaw JA, Suzuki T.  Circulating cell-free DNA levels are associated with adverse outcomes in heart failure; testing liquid biopsy in heart failure.  Eur J Prev Cardiol. 2020:2047487320912375.
Salzano A, Israr MZ, Yazaki Y, Heaney LM, Kanagala P, Singh A, Arnold JR, Gulsin GS, Squire IB, McCann GP, Ng LL, Suzuki T. Combined use of trimethylamine N-oxide with BNP for risk stratification in heart failure with preserved ejection fraction: findings from the DIAMONDHFpEF study. Eur J Prev Cardiol. 2019:2047487319870355.
Yazaki Y, Salzano A, Nelson CP, Voors AA, Anker SD, Cleland JG, Lang CC, Metra M, Samani NJ, Ng LL, Suzuki T.  Geographical location affects the levels and association of trimethylamine N‐oxide with heart failure mortality in BIOSTAT‐CHF: a post-hoc analysis. Eur J Heart Fail. 2019 Jul 28. doi: 10.1002/ejhf.1550.
Cassambai S, Salzano A, Yazaki Y, Bernieh D, Wong M, Israr MZ, Heaney LM, Suzuki T.  Impact of acute choline loading on circulating trimethylamine N-oxide levels. Eur J Prev Cardiol. 2019 18:2047487319831372.
Suzuki T, Yazaki Y, Voors AA, Jones DJL, Chan DCS, Anker SD, Cleland JG, Dickstein K, Filippatos G, Hillege HL, Lang CC, Ponikowski P, Samani NJ, Van Veldhuisen DJ, Zannad F, Zwinderman AH, Metra M, Ng LL.  Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF).  Eur J Heart Fail. 2019;21:877-886.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators. Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research. Circulation. 2018;137:1846-60.
Israr MZ, Heaney LM, Ng LL, Suzuki T.  B-type Natriuretic Peptide Molecular Forms for Risk Stratification and Prediction of Outcome after Acute Myocardial Infarction.   Am Heart J. 2018;200 37-43.
Suzuki T, Israr Z, Heaney LM, Takaoka M, Squire IB, Ng LL.  Prognostic role of molecular forms of B-type natriuretic peptide in acute heart failure.  Clin Chem. 2017;63:880-6.


Topics would include - biomarkers (metabolomics/proteomics) and integration with data science (cohort science) from translational/clinical applications/uses.


Analytical/data sciences (cohorts/biomarkers), clinical science.

Press and media

Biomarkers (including aortic diseases and gut microbiome in heart disease), clinical science/medicine (aortic/vascular).


Director, Leicester Life Sciences Accelerator
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