Portfolio

Microscopic CoronavirusSince 2014, LD3 has secured seven consecutive rounds of funding from the MRC CiC translational scheme with over 3.1M being awarded to date including our recent 2020 award of £647K. During the last two years (2018 – 2019), LD3 has successfully supported 26 projects across the College of Life Science. Priority research areas include, but are not limited to, respiratory sciences, cardiovascular diseases, oncology and infectious diseases.

LD3’s current focus is on the development of molecular diagnostics, imaging technologies, diagnostic devices and the validation of clinically relevant biomarkers for drug efficacy monitoring or prediction of treatment response/failure.

Examples of successful applications

Bacterial aerosol sampling device (MASS)

  • Prof Mike Barer (Respiratory Sciences)
  • Device development and Diagnostics

Application of a phage-PCR based technology to develop novel diagnostic tools for Tuberculosis

  • Pranab Haldar (Respiratory sciences)
  • Development of Molecular Diagnostics

Creating a decoy trap to block Covid19 

  • Nick Brindle (MCB) Leicester Institute of Structural and Chemical Biology (LISCB)
  • Drug Discovery

Establishing the Leicester Molecular Diagnostics (LMD) facility

  • Stratification of patients to targeted therapies through liquid and tissue biopsy
  • Caroline Cowley (Leicester Cancer Research Centre)

Application of artificial intelligence in paediatric Ophthalmology

  • Mervyn Thomas (Department of Neuroscience, Psychology and Behaviour)
  • Interdisciplinary project – Diagnostics and Medical Imaging

The fail-safe interatrial shunt device

  • Dave Adlam (Cardiovascular Sciences)
  • Device Development