Nuclear magnetic resonance spectroscopy

Nuclear magnetic resonance (NMR) in the Department of Chemistry is provided by three state-of-the-art, high-resolution solution state instruments. This service is available to both undergraduates and postgraduates for applications such as confirmation of target synthesis, purity analysis and structure elucidation.

The service is also available on a contractual basis. Contact Vanessa Timmermann for more details: chemnmr@le.ac.uk

drx400Bruker DRX400

  • Location: George Porter Building, lower ground floor, -1.20
  • Primary use: Postgraduate research
  • Access: Open access with sample changer
  • Probe: QNP (1H / 13C / 31P / 19F)
  • Variable temperature: High and low temperature available

About

The DRX400 spectrometer is primarily for postgraduate research purposes. 

It is equipped with a 60 position sample changer which is controlled and accessed using ICONNMR software. 

The spectrometer is mostly used to obtain 1H NMR and 19F NMR spectra. 13C{1H} and 2D spectra – such as COSY and HMQC – should be submitted for overnight accumulation after 5pm on weekdays or at weekends.

Non-routine use (for variable temperature spectra, for example) of the DRX400 can be booked by contacting the service manager (Vanessa) to arrange a time.

av500Bruker AV500

  • Location: George Porter Building, first floor, 1.03
  • Primary use: Undergraduate teaching
  • Access: Open access with sample changer
  • Probe: BBO 5mm – Z gradient (1H / 31P - 109Ag)
  • Variable temperature: Limited high temperature available

About

The AV500 spectrometer is the open access NMR spectrometer for undergraduates. Postgraduate research workers may use the spectrometer when undergraduate lab classes are not running.

It is equipped with a 5mm BBO probe and a 60 position sample changer which is controlled and accessed using ICONNMR software.

13C{1H} and 2D spectra – such as COSY and HSQC – should be submitted for overnight accumulation after 5pm on weekdays or at weekends. For NMR experiments not in the automation window, please consult the service manager (Vanessa).

av400Bruker AV400

  • Location: George Porter Building, second floor, 2.02
  • Primary use: Postgraduate research
  • Access: Restricted open access with sample changer
  • Probe: BBFO 5mm – Z gradient (1H / 19F / 15N - 31P)
  • Variable temperature: High temperature available

About

The AV400 spectrometer is the chemistry department’s newest NMR spectrometer. Samples can be submitted to the service manager (Vanessa) for manual acquisition. Trained postgraduate students are allowed acquisition manually whereas all postgraduate workers may use the spectrometer under automation control.

The spectrometer has a 5mm BBFO probe and a 60 position sample changer which is controlled and accessed using ICONNMR software.

It is capable of running a wide range of 1D and 2D spectra on a multitude of NMR nuclei, as well as DOSY spectra.