Leicester Institute of Structural and Chemical Biology

LISCB Doctoral Training Programme

Overview

To introduce PhD students to the full extent of technical capabilities and resources in the Leicester Institute of Structural and Chemical Biology (LISCB), we have established a doctoral training programme for each new PhD cohort. By following this training element in the research degree, we hope for students to develop independence and a critical way of thinking, and become equipped with technical expertise beyond the specific tools and method used in their projects. The first year of the training programme is focussed on building skills across a broad range of techniques in structural and chemical biology. Subsequent years of the training programme are focussed on transferable skills, building independence and preparation for post-degree careers.

The training programme will supplement other activities offered by the Doctoral College and schools and departments.

Aims

  • To equip students, who have undergraduate training in different subject disciplines, with a practical knowledge of the techniques used in structural and chemical biology.
  • To connect practical aspects of structural and chemical biology to theory, and thereby creating coherence to further the student’s understanding and aptitude to research at the interface of traditional academic disciplines.
  • To enable students to understand the place of their individual projects in the wider research context.
  • To enable students to gain greater independence as doctoral candidates and, thereby, being prepared for the next stage of their career.
  • To create a cohort of first-year PhD students, and increase the sense of community in LISCB.

Journal Clubs

Journal clubs will take place on Friday mornings (9.00am, Common room) at the dates interleaved between the main session listed below. These will tie in with the subject material taught in the previous week. The journal club is open to all PhD students (1st, 2nd, 3rd and 4th years) in LISCB, Chemistry, Respiratory Sciences and MCB.

Research in Progress Seminars

Every Friday 12.30pm members of the department will give short presentations on their ongoing research.

Schedule

Date Topic
14 October 2022

Welcome
Introduction to Structural and Chemical Approaches to Biology

28 October 2022 Molecular biology I
11 November 2022 Molecular biology II
25 November 2022 Sample preparation protein and nucleic acid purification
9 December 2022 CryoEM from sample to grid to data to structure
13 January 2023 Biophysical techniques to explore biological systems
27 January 2023 X-ray from sample to crystal to data to structure
10 February 2023 NMR from sample to spectra to structure
24 February 2023 NMR dynamics
10 March 2023 Advanced fluorescence microscopy
24 March 2023 Single molecule microscopy I
21 April 2023 Single molecule microscopy II
5 May 2023 Methods and approaches in Chemical Biology molecular design, synthetic techniques
19 May 2023 Methods and approaches in Chemical Biology synthetic techniques
2 June 2023 Numerical skills training
Python programming
16 June 2023 Machine learning/AI
30 June 2023 Bioinformatics
14 July 2023 Applying structural and chemical biology to clinical research and drug discovery

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