Leicester Cancer Research Centre


The primary remit of the Leicester ECMC is to support early phase oncology clinical trials and translational research programmes. Our early phase trial portfolio is run through the Hope Clinical Trials Centre which is directed by our ECMC clinical lead, Prof Anne Thomas. HCTC benefits from ECMC-funded trials pharmacy and nursing support. On average each year, the facility hosts nearly 4000 patient visits.

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Clinical trial planning and work-up

HCTC has capability to deliver first-in-man and early phase academic and commercial trials which are often part of key national and international multi-site studies. If you wish to bring a study into the portfolio, all enquiries should be directed to Prof Anne Thomas or Lydianne Lock in the first instance.
Prior to any formal trial work-up for progression to Green Light status, project approval must be obtained through the Cancer Research Strategy Board to ensure that there is sufficient capacity and staffing to undertake the proposed work. 

Statistical support

Statistical support in trial design, sample size calculation, writing and reviewing statistical analysis plans (SAP), trial end-point analyses and dissemination can be applied for through our ECMC trials statistician based at the Leicester Clinical Trials Unit.  The Statistician has a particular interest in statistical programming and automation of results procedures to improve data output efficiency. Applications can be made by filling out the ECMC Stats Collaboration Request Form

ECMC study support

The ECMC research and tissue collection team are able to support study-related paperwork and ethical submissions for non CTIMPs. In addition, applications can be made to support sample collection and processing from across Leicester’s hospital sites. Priority will be given to support: phase I clinical trials; multi-centre consortia; short term support to accelerate research outputs; support for new academics; where key staff are on long-term leave; where samples support numerous research projects.
All enquiries should be directed to the ECMC translational research manager, Dr Lynne Howells in the first instance.

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