MMC Projects

 2017

• Mathematicians develop theory which helps to unravel long-standing mysteries of animal movement How environment plays key role in changing movement behavior of animals) - press release on ScienceDaily
• Six degrees of separation: Why it is a small world after all. Study examines how small-world networks occur within bigger and more complex structures - press release on ScienceDaily
• Nomination for the Research Impact Award: Pattern Recognition in Big Data. Researchers: Professor Alexander Gorban, Professor Jeremy Levesley, Dr Ivan Tyukin, Dr Evgeny Mirkes, Dr Andrey Mudrov, Mathematical Sciences.
• High praise for Leicester data mining team’s research into trauma patient deaths (news story, 11 May 2017) - the paper E.M. Mirkes, T.J. Coats, J. Levesley, A.N. Gorban, Handling missing data in large healthcare dataset: a case study of unknown trauma outcomes, Computers in Biology and Medicine 75 (2016), 203-216 is highlighted by the journal 'Computers in Biology and Medicine'  as ‘honoured’ and ‘esteemed’
• Blessing of Dimensionality: One-Trial Correction of Legacy Artificial Intelligence (AI) Systems - press release on ScienceDaily: Helping robots correct errors on-the-fly and learn from each other

2016

• Development of new screening tool for toxic chemicals, with Department of Chemistry - press-release in ScienceDaily
• Handling missing data in large healthcare datasets, with TARN - press release in ScienceDaily: Trauma patient deaths peak at two weeks
• Systems Medicine: Novel Mathematical Approaches to Personalised Care in Asthma Patients with Respiratory Biomedical Research Unit/Department of Infection, Immunity & Inflammation.
• Evolution of adaptation mechanisms - press release in ScienceDaily
• Capillarity of Ideal Gas: Beyond Navier--Stokes equations - press release in ScienceDaily: New capillarity effects in ideal gases solve an old mathematical mystery.

 2014

• Modelling of global epigenetic changes in pneumococcus, with Department of Genetics - press-release in ScienceDaily: Breakthrough study discovers six changing faces of 'global killer' bacteria
• Computational diagnosis and risk evaluation for canine lymphoma, with Avacta Animal Health - Press release in ScienceDaily: New hope for beloved family pets: New blood test for canine cancer 

2012

• Mathematical Modeling of microRNA-Mediated Mechanisms of Translation Repression and Analysis of microRNA modes of action - press release in ScienceDaily: Mathematicians solve decade-old debate on regulation of protein production by microRNAs in cells  

2011

• Efficient Visual Intelligence Technologies with Industrial partners, supported by Innovate UK, two KTP projects) - the project aimed at developing computationally efficient methods, algorithms and tools in the area of intelligent image processing

2010

• Correlation, Risk and Crisis - press release in ScienceDaily 

2008

• Computational diagnosis and risk evaluation for canine lymphoma, with Avacta Animal Health - Press release in ScienceDaily: New hope for beloved family pets: New blood test for canine cancer 
• A Radulescu, A Gorban, A Zinovyev and A Lilienbaum. Robust Simplifications of Multiscale Biochemical Networks. BMC Systems Biology 2008, 2:86, doi:10.1186/1752-0509-2-86
• Mathematics explains puzzles of icy dust in the outer space: Analysis of the Cassini spacecraft's data on cryo-volcanic activity on Enceladus showed icy particles (dust) are the main source of Saturn's E ring. Based on this, a quantitative mathematical model by Dr Nikolay Brilliantov and colleagues explains the observed properties of the plumes. The results favor conditions of liquid water near Enceladus' surface, implying an 'underground' ocean which may be a habitat for life - the results are published in Nature, vol. 451, p.685 (2008), press release in The New York Times, in Astronomy and Science Daily

2007

• Mathematical Modelling of Brain, with international team from Japan and The Netherlands - University press release: Brain Power - Breakthrough in Mathematical Modelling
• Branching Principal Components, Principal Cubic Complexes and Topological Grammars

2006

• Cartography of Ratings results of the Political Atlas of the World

Knowledge Transfer Partnership (KTP) projects funded by Innovate UK foundation

• KTP009890 between ARM/Apical Ltd and the University of Leicester (Efficient Visual Intelligence Technologies), 2015-2017, Knowledge Base Supervisor Dr I.Y. Tyukin, lead academic Prof A.N. Gorban
• KTP010522 between Visual Management Systems Limited and the University of Leicester (Efficient Visual Intelligence Technologies), 2017-2019, Knowledge Base Supervisor Dr I.Y. Tyukin, lead academic Prof A.N. Gorban
• KTP010604 between Dataffirm Limited and the University of Leicester (Mining of Big Text Data), 2017-2019, Knowledge Base Supervisor Dr E.M. Mirkes, lead academic Prof A.N. Gorban
• KTP 10819 between Photek Ltd and the University of Leicester to develop a product range of image intensifiers enhanced with data analytics capabilities, 2017-2020, Knowledge Base Supervisor Dr A. Mudrov, Lead Academic Dr I.Y. Tyukin.

Industrial projects

With Weatherford Int.

• the magnetic flux leakage (MFL) method for the detection of defects in ferromagnetic (steel) tubulars. MFL identifies the position, size and shape of corrosion-related defects in steel casings used to protect boreholes drilled into oil and gas reservoirs.
• With Weatherford Int. Algorithms and software for pseudo-outcrop visualization of borehole and full-diameter rock core images to augment the ubiquitous unwrapped cylinder view and thereby assist non-specialist interpreters.
• With Weatherford Int. Lattice Boltzmann modelling of permeability and relative permeability of porous media for multi-phase flows.

With ARM/Apical Ltd.

• Detection and Tracking of Objects in Live Video Streams, learning models of tracking objects online and software library for intellectual analysis of video stream.
  - Scene Analysis Assisting for AWB Using Binary Decision Trees and Average Image Metrics
  - Learning Optimization for Decision Tree Classification of Non-categorical Data

With Avacta Animal Health.

• Computational diagnosis and risk evaluation for canine lymphoma - press release in ScienceDaily

With British Geological Survey, University of Bristol, and University of Leeds.

• Quaternary hydrate stability
  - Sensitivity of the global submarine hydrate inventory to scenarios of future climate change
  - Forecasting diffusive formation of free-gas methane layers in sea sediments

With British Geological Survey.

• Data mining for geological information: algorithms and software for data mining with uncertainty evaluation.

Biomedical projects

• Development new screening tool for toxic chemicals, with Department of Chemistry - Press release in ScienceDaily
• Mathematical Modeling of microRNA-Mediated Mechanisms of Translation Repression and Analysis of microRNA modes of action - press release in ScienceDaily: Mathematicians solve decade-old debate on regulation of protein production by microRNAs in cells  
• Modelling of global epigenetic changes in pneumococcus, with Department of Genetics - press-release in ScienceDaily: Breakthrough study discovers six changing faces of 'global killer' bacteria
• Handling missing data in large healthcare datasets, with TARN - press release in ScienceDaily: Trauma patient deaths peak at two weeks

Other highlights

• Fluorescence-based assay as a new screening tool for toxic chemicals: Our study involves development of fluorescent cell-based diagnostic assay as a new approach in high-throughput screening method
• Piece-wise quadratic approximations of arbitrary error functions for fast and robust machine learning
• Evolution of adaptation mechanisms: Adaptation energy, stress, and oscillating death
• Kinetic signatures of microRNA modes of action: having created a mathematical model that combines nine known mechanisms of miRNA action and estimated the model parameters from the literature, we have developed a computational tool for discriminating among different possible individual mechanisms of miRNA action based on translation kinetics data that can be experimentally measured (kinetic signatures).