People
Dr Erol Gaillard
Associate Professor
School/Department: Respiratory Sciences, Department of
Telephone: +44 (0)116 252 3261
Email: eag15@leicester.ac.uk
Publications
PUBLICATIONS
Gawlik-Lipinski A, Hassen S, Ramphul M, Gaillard EA, Quint JK, Gillies CL, Lo D. Risk Factors for Life-Threatening Asthma Attacks and Asthma-Related Mortality in Children-A Systematic Review. Pediatr Pulmonol. 2025 Aug;60(8):e71255. doi: 10.1002/ppul.71255.
Lo D, Lawson C, Broomfield J, Gillies C, Shabnam S, Gaillard EA, Pinnock H, Quint J. Risk factors for recurrent attacks of wheeze in preschool children: a population-based cohort study in England. Arch Dis Child. 2025 Jun 20:archdischild-2024-328375. doi: 10.1136/archdischild-2024-328375.
Cottini M, Poto R, Bhattacharjee A, Galant S, Lipworth B, Gaillard EA, Greig R, Berti A, Lombardi C, Menzella F, Ventura L, Comberiati P, Chan R. Characterizing the preserved ratio impaired spirometry phenotype in all severities of asthma. Respir Med. 2025 Aug;244:108180. doi: 10.1016/j.rmed.2025.108180.
Diver S, Symon F, Satchwell J, Lipscombe H, Green RH, Woltmann G, Roland D, Gaillard EA, Hansell A, Brightling C, Cuthbertson L. Under the weather: an epidemic thunderstorm asthma event in Leicester, June 2023. BMJ Open Respir Res. 2025 Apr 17;12(1):e002588. doi: 10.1136/bmjresp-2024-002588.
Ryan D, Kocks JWH, Williams S, Correia de Sousa J, Barne M, Bates MJ, Bouloukaki I, Daines L, Gaillard E, Mak V, Ostrem A, Barnard A. The asthma diagnosis jigsaw puzzle: An adaptable teaching concept to facilitate the diagnosis of asthma in adults and children presenting to primary care. NPJ Prim Care Respir Med. 2025 Mar 15;35(1):14. doi: 10.1038/s41533-024-00410-w.
Seear PJ, Welsh KG, Satchwell J, Patel D, Pashley CH, Wardlaw AJ, Gaillard EA. Positive sputum fungal culture, fungal sensitisation, and airway microbial diversity in asthmatic children. Med Mycol. 2025:25;63 doi: 10.1093/mmy/myaf005.
Chan R, Gochicoa-Rangel L, Cottini M, Comberiati P, Gaillard EA, Ducharme FM, Galant SP. Ascertainment of small airway dysfunction using oscillometry to better define asthma control and future risk: are we ready to implement it in clinical practice? Chest. 2025 May;167(5):1287-1296. doi: 10.1016/j.chest.2024.12.020.
Aliaroof M, Ibrahim W, Aung H, Cordell RL, Wilde MJ, Richardson M, Salman D, Singapuri A, Free RC, Gaillard E, Thomas P, Monks PS, Brightling CE, Siddiqui S, Greening NJ.. Oscillometry to assess ventilation heterogeneity during hospital admission for acute cardiorespiratory illness. ERJ Open Res. 2025 Jun 23;11(3):00351-2024. doi: 10.1183/23120541.00351-2024.
Pan D, Martin CA, Nazareth J, Sze S, Al-Oraibi A, Gogoi M, Grolmusova N, Divall P, Decker J, Fletcher E, Williams C, Hay J, Baggaley RF, Wyllie AL, Stephenson I, Gaillard E, Nellums LB, Clark TW, Van-Tam JN, Cowling BJ, Hollingsworth TD, Gray L, Barer M, Pareek M. Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infectiousness: a protocol for a systematic review and meta-analysis. BMJ Open. 2024 Dec 2;14(12):e085127. doi: 10.1136/bmjopen-2024-085127.
Khaleva E, Brightling C, Eiwegger T, Altraja A, Bégin P, Blumchen K, Bossios A, Bourdin A, Ten Brinke A, Brusselle G, Silvia Bumbacea R, Bush A, Casale TB, Clarke GW, Chaudhuri R, Fan Chung K, Coleman C, Corren J, Dahlén SE, Deschildre A, Djukanovic R, Eger K, Exley A, Fleming L, Fowler SJ, Gaillard EA, Gappa M, Gupta A, Michael Haitchi H, Hashimoto S, Heaney LG, Hedlin G, Henderson M, Hua W, Jackson DJ, Karadag B, Helen Katelaris C, Koh MS, Volkmar Kopp M, Koppelman GH, Kull I, Kurukulaaratchy RJ, Lee JH, Mahler V, Mäkelä M, Masoli M, Mathioudakis AG, Mazon A, Melén E, Milger K, Moeller A, Murray CS, Nagakumar P, Nair P, Negus J, Nieto A, Papadopoulos NG, Paton J, Pijnenburg MW, Pike KC, Porsbjerg C, Rattu A, Rupani H, Rusconi F, Rutjes NW, Saglani S, Seddon P, Siddiqui S, Singer F, Tajiri T, Turner S, Upham JW, Vijverberg SJH, Wark PAB, Wechsler ME, Yasinska V, Roberts G. Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma. Eur Respir J. 2024 Nov 7:2400691. doi: 10.1183/13993003.00691-2024.
Hakizimana A, Lo DKH, Roland D, Rai VK, Danvers L, Rowlands R, Ahmed MI, Herzallah R, Gaillard EA. Effectiveness of paediatric asthma hubs: a clinical pilot study. Arch Dis Child. 2024 Oct 29:archdischild-2023-326635. doi: 10.1136/archdischild-2023-326635.
Lo D, Lawson C, Gillies C, Shabnam S, Gaillard EA, Pinnock H, Quint JK. Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study. Thorax. 2024 Oct 16;79(11):1050-1059. doi: 10.1136/thorax-2023-221210.
Roy M, Ramphul M, Gronnier M, Divall P, Lemaire-Paquette S, Ducharme F, Cote A, Gaillard E, Couillard S. Diagnostic accuracy of fractional exhaled nitric oxide (FeNO) with or without blood eosinophils in childhood, adolescent, and adult asthma: protocol for a systematic review and meta-analysis. medRxiv 2024.07.14.24310394; doi: https://doi.org/10.1101/2024.07.14.24310394.
Hakizimana A, Devani P, Gaillard EA. Current technological advancement in asthma care. Expert Rev Respir Med. 2024 Jul;18(7):499-512. doi: 10.1080/17476348.2024.2380067.
Cornelius V, Babalis D, Carroll WD, Cunningham S, Fleming L, Gaillard E, Gupta A, Janani L, Kennington E, Murray C, Nagakumar P, Roberts G, Seddon P, Sinha I, Streatfield C, Weir E, Saglani S. Treating severe paediatric asthma with mepolizumab or omalizumab: a protocol for the TREAT randomised non-inferiority trial. BMJ Open. 2024 Aug 21;14(8):e090749. doi: 10.1136/bmjopen-2024-090749.
Ahmed MI, Dayman N, Blyth N, Madge J, Gaillard E. Impact of CFTR Modulators on exercise capacity in adolescents with cystic fibrosis. ERJ Open Res. 2024 Feb 19;10(1):00687-2023. doi: 10.1183/23120541.00687-2023.
Riveron TP, Wilde MJ, Ibrahim W, Carr L, Monks PS, Greening NJ, Gaillard EA, Brightling CE, Siddiqui S, Hansell AL, Cordell RL. Characterisation of volatile organic compounds in hospital indoor air and exposure health risk determination. Building and Environment 2023;242: https://doi.org/10.1016/j.buildenv.2023.110513.
Paracha R, Lo DKH, Montgomery U, Ryan L, Varakantam V, Gaillard EA. Relationship between asthma medication adherence, asthma attacks and lung function parameters in children managed in UK primary care. NPJ Prim Care Respir Med. 2023 Mar 25;33(1):12. doi: 10.1038/s41533-022-00323-6.
Mallet MC, Mozun R, Pedersen ESL, Ardura-Garcia C, Gaillard EA, Latzin P, Moelller A, Kuehni CE; LUIS study group. Prevalence of childhood cough in epidemiological studies depends on the question used: findings from two population-based studies. Swiss Med Wkly. 2023 Mar 8;153:40044. doi: 10.57187/smw.2023.40044.
Alshlowi M, Hakizimana A, Alraimi A, Devani P, Lundblad LKA, Beardsmore CS, Gaillard EA. Differences in respiratory oscillometry measurements using mouthpiece, mouth, and nasal mask in healthy adults. J Appl Physiol (1985). 2023 Jan 1;134(1):142-146. doi: 10.1152/japplphysiol.00491.2022.
Wadah I., Wilde M.J., Cordell R.L., Richardson M., Salman D., Free R.C., Zhao B., Singapuri A., Hargadon B., Gaillard EA, Suzuki T., Ng L.L., Coats T., Thomas P., Monks P.S., Brightling CE, Greening NJ, Siddiqui S. Visualisation of exhaled breath metabolites reveals distinct diagnostic signatures for acute cardiorespiratory breathlessness. Sci Transl Med 2022, Vol 14, doi: 10.1126/scitranslmed.abl5849.
Khaleva E, Rattu A, Brightling C, Bush A, Bossios A, Bourdin A, Chung KF, Chaudhuri R, Coleman C, Dahlén SE, Djukanovic R, Deschildre A, Fleming L, Fowler SJ, Gupta A, Hamelmann E, Hashimoto S, Hedlin G, Koppelman GH, Melén E, Murray CS, Pilette C, Porsbjerg C, Pike KC, Rusconi F, Williams C, Ahrens B, Alter P, Anckers F, van den Berge M, Blumchen K, Brusselle G, Clarke GW, Cunoosamy D, Dahlén B, Dixey P, Exley A, Frey U, Gaillard EA, Giovannini-Chami L, Grigg J, Hartenstein D, Heaney LG, Karadag B, Kaul S, Kull I, Licari A, Maitland-van der Zee AH, Mahler V, Schoos AM, Nagakumar P, Negus J, Nielsen H, Paton J, Pijnenburg M, Ramiconi V, Vilarnau SR, Principe S, Rutjes N, Saglani S, Seddon P, Singer F, Staudinger H, Turner S, Vijverberg S, Winders T, Yasinska V, Roberts G; COMSA working group in the 3TR consortium. Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA). Eur Respir J. 2023 Apr 3;61(4):2200606. doi: 10.1183/13993003.00606-2022.
Devani P, Lo DKH, Gaillard EA. Practical approaches to the diagnosis of asthma in school-age children. Expert Rev Respir Med. 2022 Sep 22:1-9. doi: 10.1080/17476348.2022.2126355.
Turner S, Cotton S, Wood J, Bell V, Raja EA, Scott NW, Morgan H, Lawrie L, Emele D, Kennedy C, Scotland G, Fielding S, MacLennan G, Norrie J, Forrest M, Gaillard E, de Jongeste J, Pijnenburg M, Thomas M, Price D. Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT. Southampton (UK): National Institute for Health and Care Research; 2022 May.PMID:35679443.
Teo KW, Patel D, Sisodia S, Roland D, Gaillard EA, Tang JW. Rhinovirus persistence during the COVID-19 pandemic-Impact on pediatric acute wheezing presentations. J Med Virol. 2022 Nov;94(11):5547-5552. doi: 10.1002/jmv.27986.
Turner S, Cotton S, Wood J, Bell V, Raja EA, Scott NW, Morgan H, Lawrie L, Emele D, Kennedy C, Scotland G, Fielding S, MacLennan G, Norrie J, Forrest M, Gaillard EA, de Jongste J, Pijnenburg M, Thomas M, Price D. Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial. Lancet Respir Med. 2022 Jun;10(6):584-592. doi: 10.1016/S2213-2600(21)00486-0.
Bhavra K, Wilde M, Richardson M, Cordell R, Thomas P, Zhao B, Bryant L, Brightling CE, Ibrahim W, Salman D, Siddiqui S, Monks P, Gaillard EA. The utility of a standardised breath sampler in school age children within a real-world prospective study. J Breath Res. 2022;16. doi: 10.1088/1752-7163/ac5526.
Ramphul M, Welsh KG, May RD, Ghebre MA, Rapley L, Woods J, Cohen ES, Herath A, Monteiro W, Rousseau K, Thornton DJ, Brightling CE, Gaillard EA. Sputum biomarkers during acute severe asthma attacks in children- a case-control study. Acta Paediatr. 2022 Mar;111(3):620-627. doi: 10.1111/apa.16186.
Holden K, Makinde M, Wilde M, Richardson M, Coats T, Monks P, Gaillard EA. Assessing the feasibility and acceptability of online measurements of exhaled volatile organic compounds (VOCs) in children with preschool wheeze: a pilot study. BMJ Paediatr Open. 2021;5(1):e001003. doi: 10.1136/bmjpo-2020-001003.
Ramphul M, Gaillard EA. Diagnosis and management of acute asthma in children. Practitioner. June 2021; 265(1849):17-21.
Wardlaw AJ, Rick E, Ozyigit LP, Scadding A, Gaillard EA, Pashley CH. New perspectives in the diagnosis and management of Allergic Fungal Airway Disease. J Asthma Allergy. 2021;14:557-573. doi: 10.2147/JAA.S251709.
Lo DKH, Beardsmore C, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA. Risk Factors for Asthma Attacks and Poor Control in Children: A Prospective Observational Study in UK Primary Care. Arch Dis Child. 2022 Jan;107(1):26-31. doi: 10.1136/archdischild-2020-320110.
Nuttall A, Beardsmore CE, Gaillard EA. Ventilation Heterogeneity in Children with Severe Asthma. Eur J Pediatr. 2021;180:3399-3404.
Ramphul M, Lo DKH, Gaillard EA. Precision medicine for paediatric severe asthma: current status and future direction. J Asthma Allergy. 2021;14:525-538. doi: 10.2147/JAA.S265657.
Gaillard EA, Moeller A. Evidence-based European guidelines for the diagnosis of asthma in children aged 5–16 years. Lancet Respir Med. 2021 Jun;9(6):558-560. doi: 10.1016/S2213-2600(21)00183-1.
Yang Y, Lo DKH, Beardsmore C, Roland D, Richardson M, Danvers L, Wilson A, Gaillard EA. Implementing Spirometry and Fractional Exhaled Nitric Oxide (FeNO) Testing in Childhood Asthma Management in UK primary care – an observational study to examine training and implementation cost and impact on patient’s health utilization and outcome. Arch Dis Child. 2022 Jan;107(1):21-25. doi: 10.1136/archdischild-2020-319310.
Gaillard EA, Kuehni CE, Turner S, Goutaki M, Holden KA, de Jong C, Lex C, Lo DKH, Lucas JS, Midulla F, Mozun R, Piacentini G, Rigau D, Rottier B, Thomas M, Tonia T, Usemann J, Yilmaz O, Zacharasiewicz A, Moeller A. European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5 to 16 years. Eur Respir J 2021;4:58:2004173 doi: 10.1183/13993003.04173-2020.
Patel D, Dacanay KC, Pashley CH, Gaillard EA. Comparative Analysis of Clinical Parameters and Sputum Biomarkers in Establishing the Relevance of Filamentous Fungi in Cystic Fibrosis. Front Cell Infect Microbiol. 2021 Jan 22;10:605241. doi: 10.3389/fcimb.2020.605241.
Zhao B, Bryant L, Cordell R, Wilde M, Salman D, Ruszkiewicz D, Ibrahim W, Singapuri A, Coats T, Gaillard E, Beardsmore C, Suzuki T, Ng L, Greening N, Thomas P, Monks P, Brightling C, Siddiqui S, Free RC. LabPipe: an extensible bioinformatics toolkit to manage experimental data and metadata. BMC Bioinformatics. 2020 Dec 2;21(1):556. doi: 10.1186/s12859-020-03908-5.
Welsh KG, Holden KA, Wardlaw AJ, Satchwell J, Monteiro W, Pashley CH, Gaillard EA. Fungal sensitization and positive fungal culture from sputum in children with asthma are associated with reduced lung function and acute asthma attacks respectively. Clin Exp Allergy. 2021 Jun;51(6):790-800. doi: 10.1111/cea.13799.
Gaillard EA. Improving the management of chronic asthma in children. Practitioner December 2020;264 (1843): 11-14.
Ardura-Garcia C, Cuevas-Ocaña S, Freitag N, Kampouras A, King JA, Kouis P, Mensink-Bout SM, Whitehouse AL, Williams E, Dassios T, Duijts L, Ersu RH, Gaillard EA, Horsley AR, Proesmans M, Rottier R, Schramm D, Moeller A, Pijnenburg MW. ERS International Congress 2020 virtual: highlights from the Paediatric Assembly. ERJ Open Res. 2021 Mar 22;7(1):00893-2020. doi: 10.1183/23120541.00893-2020.
Moeller A, Thanikkel L, Duijts L, Gaillard E, Garcia-Marcos L, Kantar A, Tabin N, Turner S, Zacharasiewicz A, Pijnenburg M. Covid-19 infection in children with underlying chronic respiratory diseases: survey results from 147 centers. ERJ Open Res. 2020 Oct 26;6(4):00409-2020. doi: 10.1183/23120541.00409-2020.
Roland D, Teo K, Bandi, S, Lo D, Gaillard EA. COVID-19 is not a driver of clinically significant viral wheeze and asthma. Arch Dis Child. 2021 Apr;106(4):e22. doi: 10.1136/archdischild-2020-320776.
Holden KA, Ibrahim W, Salman D, Cordell R, McNally T, Patel B, Phillips R, Beardsmore C, Wilde M, Bryant L, Singapuri A, Monks P, Brightling C, Greening N, Thomas P, Siddiqui S, Gaillard EA. Use of the ReCIVA device in breath sampling of patients with acute breathlessness: a feasibility study. ERJ Open Res. 2020 Nov 23;6(4):00119-2020. doi: 10.1183/23120541.00119-2020.
Jurca M, Goutaki, M, Latzin P, Gaillard EA, Spycher BD, Kuehni CE. Isolated night cough in children: how does it differ from wheeze? Eur Respir J Open.2020. doi: 10.1183/23120541.00217-2020.
Lo DK, Beardsmore CS, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA. Feasibility and acceptability of spirometry and FeNO testing for children’s asthma in UK primary care: a prospective observational cohort study. Br J Gen Pract. 2020 Oct 29;70(700):e809-e816. doi: 10.3399/bjgp20X713033.
Lo DK, Beardsmore CS, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA. Lung function and asthma control in school-age children managed in UK primary care: a cohort study. Thorax. 2020 Feb;75(2):101-107. doi: 10.1136/thoraxjnl-2019-213068.
Turner S, Cotton SC, Emele CD, Thomas R, Fielding S, Gaillard EA, de Jongste JC, Morgan H, Neilson AR, Norrie J, Pijnenburg M, Price D, Thomas M. Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy: a randomised trial (RAACENO). Trials. 2019 Oct 4;20(1):573. doi: 10.1186/s13063-019-3500-7.
Ghebre MA, Pang PH, Desai D, Hargadon B, Newby C, Woods J, Rapley L, Cohen SE, Herath A, Gaillard EA, May RD, Brightling CE. Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum. BMC Pulm Med. 2019 Aug 8;19(1):144. doi: 10.1186/s12890-019-0906-7.
Lo D, Maniyar A, Gupta S, Gaillard E. High prevalence of bronchiectasis on chest CT in a selected cohort of children with severe Asthma. BMC Pulm Med. 2019 Jul 26;19(1):136. doi: 10.1186/s12890-019-0900-0.Nuttall A, Velásquez W, Beardsmore CS, Gaillard EA. Lung clearance index: assessment and utility in children with asthma. Eur Respir Rev. 2019 Nov 20;28(154):190046. doi: 10.1183/16000617.0046-2019.
Pedersen ESL, Spycher BD, de Jong CCM, Halbeisen F, Ramette A, Gaillard EA, Granell R, Henderson AJ, Kuehni CE. The Simple 10-Item Predicting Asthma Risk in Children Tool to Predict Childhood Asthma-An External Validation. J Allergy Clin Immunol Pract. 2019 Mar;7(3):943-953.e4. doi: 10.1016/j.jaip.2018.09.032.
Ibrahim W, Wilde M, Cordell R, Salman D, Ruszkiewicz D, Bryant L, Richardson M, Free RC, Zhao B, Yousuf A, White C, Russell R, Jones S, Patel B, Awal A, Phillips R, Fowkes G, McNally T, Foxon C, Bhatt H, Peltrini R, Singapuri A, Hargadon B, Suzuki T, Ng LL, Gaillard E, Beardsmore C, Ryanna K, Pandya H, Coates T, Monks PS, Greening N, Brightling CE, Thomas P, Siddiqui S. Assessment of breath volatile organic compounds in acute cardiorespiratory breathlessness: a protocol describing a prospective real-world observational study. BMJ Open. 2019 Mar 8;9(3):e025486. doi: 10.1136/bmjopen-2018-025486.
Wilde MJ, Cordell RL, Salman D, Zhao B, Ibrahim W, Bryant L, Ruszkiewicz D, Singapuri A, Free RC, Gaillard EA, Beardsmore C, Thomas CLP, Brightling CE, Siddiqui S, Monks PS. Breath analysis by two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection - Method optimisation and integration within a large-scale clinical study. J Chromatogr A. 2019 Jun 7;1594:160-172. doi: 10.1016/j.chroma.2019.02.001.
Ahmed MI, Kulkarni H, Shajpal S, Patel D, Patel P, Claydon A, Modha DE, Gaillard EA. Early detection of non-tuberculous mycobacteria in children with cystic fibrosis using induced sputum at annual review. Pediatr Pulmonol. 2019 Mar;54(3):257-263. doi: 10.1002/ppul.24220.
Butler MGJ, Ramphul M, Monteiro W, Taylor H, Gaillard EA. Processing small sputum samples: a method validation study. J Asthma. 2020 Feb;57(2):136-139. doi: 10.1080/02770903.2018.1553054.
Patel D, Popple S, Claydon A, Modha DE, Gaillard EA. Posaconazole therapy in children with cystic fibrosis and Aspergillus-related lung disease. Med Mycol. 2020 Jan 1;58(1):11-21. doi: 10.1093/mmy/myz015.
Danvers L, Lo DKH, Gaillard EA. The role of objective tests to support a diagnosis of asthma in children. Paediatr Respir Rev. 2019. doi: 10.1016/j.prrv.2019.02.001.
Saglani S, Bush A, Carroll W, Cunningham S, Fleming L, Gaillard E, Gupta A, Murray C, Nagakumar P, Paton J, Roberts G, Seddon P, Sinha I. Biologics for paediatric severe asthma: trick or TREAT? Lancet Respir Med. 2019 Apr;7(4):294-296. doi: 10.1016/S2213-2600(19)30045-1.
Andrews G, Lo DKH, Richardson M, Wilson A, Gaillard EA. Prospective observational cohort study of symptom control prediction in paediatric asthma by using the Royal College of Physicians three questions. NPJ Prim Care Respir Med. 2018 Oct 24;28(1):39. doi: 10.1038/s41533-018-0107-5.
Ions R, Narayanan M, Browning M, Gaillard EA, Stiefel G, Tang JW. Case presentation: persistent adenovirus B3 infections associated with bronchiolitis obliterans treated with cidofovir in a child with mosaic tetrasomy 9p. BMC Infect Dis. 2018 Oct 22;18(1):529. doi: 10.1186/s12879-018-3441-x.
Holden KA, Roland D, Welsh KG, Gaillard EA. Comparison of blood eosinophil numbers between acute asthma and stable disease in children with preschool wheeze. Pediatr Allergy Immunol Pulmonol. 2017, doi: 10.1089/ped.2017.0802.
Welsh KG, Rousseau K, Fisher G, Bonser LR, Bradding P, Brightling CE, Thornton DJ, Gaillard EA. MUC5AC and a glycosylated variant of MUC5B alter mucin composition in children with acute asthma. Chest. 2017 Oct;152(4):771-779. doi: 10.1016/j.chest.2017.07.001.
Spycher B, Cochrane C, Granell R, Sterne JAC, Silverman M, Pedersen E, Gaillard EA, Henderson J, Kuehni CE. Temporal stability of multiple trigger and episodic viral wheeze in early childhood. Eur Respir J. 2017 Nov 2;50(5):1700014. doi: 10.1183/13993003.00014-2017.
Jurca M, Ramette A, Dogaru CM, Goutaki M, Spycher BD, Latzin P, Gaillard EA, Kuehni CE. Prevalence of cough throughout childhood: A cohort study. PLoS One. 2017 May 24;12(5):e0177485. doi: 10.1371/journal.pone.0177485.
Lo D, Gaillard B, Bullous L, Gaillard E. Diagnosis and Management of Childhood Asthma in Primary Care. Practice Nursing. 2016;27:488-93.
Vardavas CI, Hohmann C, Patelarou E, Martinez D, Henderson AJ, Granell R, Sunyer J, Torrent M, Fantini MP, Gori D, Annesi-Maesano I, Slama R, Duijts L, de Jongste JC, Aurrekoetxea JJ, Basterrechea M, Morales E, Ballester F, Murcia M, Thijs C, Mommers M, Kuehni CE, Gaillard EA, Tischer C, Heinrich J, Pizzi C, Zugna D, Gehring U, Wijga A, Chatzi L, Vassilaki M, Bergström A, Eller E, Lau S, Keil T, Nieuwenhuijsen M, Kogevinas M. The independent role of prenatal and postnatal exposure to active and passive smoking on the development of early wheeze in children. Eur Respir J. 2016 Jul;48(1):115-24. doi: 10.1183/13993003.01016-2015.
Kulkarni H, Akwei S, Luyt DK, Gaillard EA, Mulla H, Pandya P (2015) Cardiac Troponin I Levels in Children with Acute Severe Asthma Treated with IV Salbutamol . Lung Dis Treat 1:102. doi:10.4172/ldt.1000102.
Saunders RV, Modha DE, Claydon A, Gaillard EA. Chronic Aspergillus fumigatus colonisation of the paediatric cystic fibrosis airway is common and may be associated with a more rapid decline in lung function. Med Mycol. 2016 Jul 1;54(5):537-43. doi: 10.1093/mmy/myv119.
Arthur GK, Duffy SM, Roach KM, Rob A. Hirst RA, Shikotra A, Gaillard EA, Bradding P. KCa3.1 K+ channel expression and function in human bronchial epithelial cells. PLoS One. 2015 Dec 21;10(12):e0145259. doi: 10.1371/journal.pone.0145259.
Haines A, Davies E, Higgins B, Menzies-Gow A, Thomas M, Masoli M, Gaillard E. Identifying The Most Cost-Effective Way of Diagnosing Asthma In Adults Using Multiple Tests - A Cost-Utility Analysis From The Nice Asthma Guideline. Value Health. 2015 Nov;18:A361.
Marshall L, Beardsmore CS, Pescatore A, Kuehni CE, Gaillard EA. Airway eosinophils in older teenagers with outgrown preschool wheeze: A Pilot study. Eur Respir J. 2015 Nov;46(5):1486-9. doi: 10.1183/13993003.00174-2015.
Gaillard EA, McNamara PS, Murray CS, Pavord ID, Shields MD. Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial? Clin Exp Allergy. 2015 Sep;45(9):1384-95. doi: 10.1111/cea.12535.
Pescatore AM, Spycher BD, Jurca M, Gaillard EA, Kuehni CE. Environmental and socioeconomic data do not improve the Predicting Asthma Risk in Children (PARC) tool. J Allergy Clin Immunol. 2015 May;135(5):1395-7.e1-3. doi: 10.1016/j.jaci.2014.10.053.
Brugha RE, Mushtaq M, Round T, Gadhvi DH, Dundas I, Gaillard E, Koh L, Fleming LJ, Lewis DJ, Sanak M, Wood HE, Barratt D, Mudway IS, Kelly FJ, Griffiths CJ, Grigg J. Carbon in airway macrophages from children with asthma. Thorax. 2014 Jul;69(7):654-9. doi: 10.1136/thoraxjnl-2013-204734.
Brand PL, Caudri D, Eber E, Gaillard EA, Garcia-Marcos L, Hedlin G, Henderson J, Kuehni CE, Merkus PJ, Pedersen S, Valiulis A, Wennergren G, Bush A. Classification and pharmacological treatment of preschool wheezing: changes since 2008. Eur Respir J. 2014 Apr;43(4):1172-7. doi: 10.1183/09031936.00199913.
Pescatore AM, Dogaru CM, Duembgen L; Silverman M, Gaillard EA, Spycher BD, Kuehni C. A simple asthma prediction tool for pre-school children with wheeze or cough. J Allergy Clin Immunol. 2014 Jan;133(1):111-8.e1-13. doi: 10.1016/j.jaci.2013.06.002.
Wain LV, Odenthal-Hesse L, Abujaber R, Sayers I, Beardsmore C, Gaillard EA, Chappell S, Dogaru CM, McKeever T, Guetta-Baranes T, Kalsheker N, Kuehni CE, Hall IP, Tobin MD, and Hollox EJ. Copy number variation of the beta-defensin genes in Europeans: No supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma. PLoS One. 2014 Jan 3;9(1):e84192. doi: 10.1371/journal.pone.0084192.
Browning MJ, Lim MTC, Kenia P, Whittle M, Doffinger R, Barcenas-Morales G, Kumararatne D, Viskaduraki M, O'Callaghan C and Gaillard EA. Pneumococcal polysaccharide vaccine responses are impaired in a subgroup of children with cystic fibrosis. J Cyst Fibros. 2014 Dec;13(6):632-8. doi: 10.1016/j.jcf.2014.02.002.
Gaillard EA, Grigg J, Tellabati A, McNally T, Whittaker A, Beardsmore CS. Isolation of cells from the lower airways in infants with wheeze by sputum induction. Eur Respir J. 2013 Feb;41(2):483-5. doi: 10.1183/09031936.
Liu JC, Modha DE, Gaillard EA. What is the clinical significance of filamentous fungi positive sputum cultures in patients with cystic fibrosis? J Cyst Fibros. 2013 May;12(3):187-93. doi: 10.1016/j.jcf.2013.02.003.
Lim MTC, Jeyarajah K, Jones P, Pandya H, Doffinger R, Kumararatne D, Browning MJ, Gaillard EA. Specific antibody deficiency in children with chronic wet cough. Arch Dis Child. 2012 May;97(5):478-80. doi: 10.1136/archdischild-2011-300691.
Gaillard EA, Kota P, Gentszch M, Dokholyan NV, Stutts MJ, Tarran R. Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases. Pflugers Arch. 2010 Jun;460(1):1-17. doi: 10.1007/s00424-010-0827-z.
Garcia-Caballero A, Rasmussen JE, Gaillard E, Watson MJ, Olsen JC, Donaldson SH, Stutts MJ, Tarran R. SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11412-7. doi: 10.1073/pnas.0903609106.
Gaillard EA, Shaw NJ, Wallace HL, Vince G, Southern KW. Electrical potential difference across the nasal epithelium is reduced in premature infants with chronic lung disease but is not associated with lower airway inflammation. Pediatr Res. 2007 Jan;61(1):77-82. doi: 10.1203/01.pdr.0000250035.10339.ce.
Eisenhut M, Wallace H, Barton P, Gaillard EA, Newland P, Diver M, Southern KW. Pulmonary edema in meningococcal septicaemia associated with reduced epithelial chloride transport. Pediatr Crit Care Med. 2006 Mar;7(2):119-24. doi: 10.1097/01.PCC.0000200944.98424.E0.
Gaillard EA, Shaw NJ, Subhedar NV, Wallace HL, Southern KW. Natal potential difference increases with gestation in moderately preterm neonates on the first postnatal day. Arch Dis Child Fetal Neonatal Ed. 2005 Mar;90(2):F172-3. doi: 10.1136/adc.2004.054494.
Gaillard EA, Carty H, Southern KW: The persistently abnormal chest radiograph in children. Current Paediatrics. 2004. doi: 10.1016/j.cupe.2004.04.012.
Bissaker S, Hindley C, Gaillard EA, Shaw NJ. The effect of pre-transfer advice, stabilisation and transport on respiratory status of infants being transported with respiratory distress syndrome. J Neonatal Nurs 2004;10:96-8.
Gaillard EA, Shaw NJ. Chronic lung disease in infancy following prematurity. Hosp Med. 2003 Nov;64(11):640-3. doi: 10.12968/hosp.2003.64.11.2341.
Gaillard EA, Carty H, Heaf D, Smyth RL. Reversible bronchial dilatation in children: comparison of serial HRCT scans of the lungs. Eur J Radiol. 2003 Sep;47(3):215-20. doi: 10.1016/s0720-048x(02)00122-5.
Gaillard EA, Shaw NJ, Subhedar NV, Wallace HL, Southern KW. Airway ion transport on the first postnatal day in infants delivered vaginally or by elective caesarian section. Pediatr Res. 2003 Jul;54(1):58-63. doi: 10.1203/01.PDR.0000069842.09976.CB.
Gaillard EA, Shaw NJ, Subhedar NV, Wallace HL, Southern KW. Employing the nasal potential difference as a diagnostic test for cystic fibrosis in neonates: potential pitfalls. J Pediatr. 2002 Aug;141(2):295-6. doi: 10.1067/mpd.2002.124978.
Gaillard EA, Cooke RWI, Shaw NJ. Improved survival and neurodevelopmental outcome following prolonged ventilation in preterm neonates who have received surfactant. Arch Dis Child Fetal Neonatal Ed. 2001 May;84(3):F194-6. doi: 10.1136/fn.84.3.f194.