Gene and genome analysis

Module code: BS7101

In this module you will study the very broad role bioinformatics plays in the fields of genetics and genomics. We will look at the basic molecular and cellular processes underlying gene expression, genome structure and evolution as well as the techniques used to study them. We will investigate genome sequencing and genome annotation, and the emerging areas of functional and comparative genomics. Since statistical analyses underpin many informatic challenges in biology, we will explore these analyses and the statistical tools supporting them (specifically the R programming language) in the context of two major application areas -transcriptomics, and molecular evolution and phylogeny. We will also consider the role of statistics in genetic mapping and genetic epidemiology.