Microbial Sciences projects

The roles of virulence proteins in infectious diseases due to Streptococcus pneumoniae

The genes that determine susceptibility to pneumonia

Bacterial sensory perception

Characterisation of the interactions of the Streptococcus pneumoniae toxin, pneumolysin, with soluble molecules of the immune system

Structural characterization of initiating components of the innate immune system

Identification of host receptors for bacteriophages which infect Clostridium difficile

The role of peptidoglycan remodelling in Listeria monocytogenes persistence

Nutritional virulence: how is the metabolism of Mycobacterium tuberculosis adapted to the pathogenic lifestyle?

Investigation of Rpf-dependency phenomenon in clinical Mycobacterium tuberculosis isolates

Regulation of protein secretion by serine/threonine protein kinases in mycobacteria

The impact of bacteriophages on pneumococcal metabolism and virulence

Understanding environmental determinants of microbial virulence as a route to design anti-infectives

Informal enquiries

If you are interested in any of these projects or require further information regarding postgraduate opportunities in the department please send an informal enquiry to Dr Caroline Beardsmore.

Funding

Please note: you will need to secure your own funding for these projects unless funding is specified.