The roles of virulence proteins in infectious diseases due to Streptococcus pneumoniae
The genes that determine susceptibility to pneumonia
Bacterial sensory perception
Characterisation of the interactions of the Streptococcus pneumoniae toxin, pneumolysin, with soluble molecules of the immune system
Structural characterization of initiating components of the innate immune system
Identification of host receptors for bacteriophages which infect Clostridium difficile
The role of peptidoglycan remodelling in Listeria monocytogenes persistence
Nutritional virulence: how is the metabolism of Mycobacterium tuberculosis adapted to the pathogenic lifestyle?
Investigation of Rpf-dependency phenomenon in clinical Mycobacterium tuberculosis isolates
Regulation of protein secretion by serine/threonine protein kinases in mycobacteria
The impact of bacteriophages on pneumococcal metabolism and virulence
Understanding environmental determinants of microbial virulence as a route to design anti-infectives
If you are interested in any of these projects or require further information regarding postgraduate opportunities in the department please send an informal enquiry to Dr Caroline Beardsmore.
Please note: you will need to secure your own funding for these projects unless funding is specified.