Publications

Below are references from the Biostatistics Research Group from 2011. The list is generated from Scopus and thus there will be a small number of references missing. See individual pages for some more details on publications and outputs.

Brilleman SL, Crowther MJ, Moreno-Betancur M, Buros Novik J, Dunyak J, Al-Huniti N, Fox R, Hammerbacher J, Wolfe R. Joint longitudinal and time-to-event models for multilevel hierarchical data. Statistical Methods in Medical Research 2019;28:3502–15.

Arnold M, Rutherford MJ, Bardot A, Ferlay J, Andersson TM-L, Myklebust TÅ, Tervonen H, Thursfield V, Ransom D, Shack L, Woods RR, Turner D, Leonfellner S, Ryan S, Saint-Jacques N, De P, McClure C, Ramanakumar AV, Stuart-Panko H, Engholm G, Walsh PM, Jackson C, Vernon S, Morgan E, Gavin A, Morrison DS, Huws DW, Porter G, Butler J, Bryant H, Currow DC, Hiom S, Parkin DM, Sasieni P, Lambert PC, Møller B, Soerjomataram I, Bray F. Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (icbp survmark-2): A population-based study. The Lancet Oncology 2019;20:1493–505.

Costa BR da, Sutton AJ. A comparison of the statistical performance of different meta-analysis models for the synthesis of subgroup effects from randomized clinical trials. BMC Medical Research Methodology 2019;19:198.

Yates T, Gray LJ, Henson J, Edwardson CL, Khunti K, Davies MJ. Impact of depression and anxiety on change to physical activity following a pragmatic diabetes prevention program within primary care: Pooled analysis from two randomized controlled trials. Diabetes Care 2019;42:1847–53.

Conrado DJ, Larkindale J, Berg A, Hill M, Burton J, Abrams KR, Abresch RT, Bronson A, Chapman D, Crowther M, Duong T, Gordish-Dressman H, Harnisch L, Henricson E, Kim S, McDonald CM, Schmidt S, Vong C, Wang X, Wong BL, Yong F, Romero K, Vishwanathan V, Chidambaranathan S, Douglas Biggar W, McAdam LC, Mah JK, Tulinius M, Cnaan A, Morgenroth LP, Leshner R, Tesi-Rocha C, Thangarajh M, Kornberg A, Ryan M, Nevo Y, Dubrovsky A, Clemens PR, Abdel-Hamid H, Connolly AM, Pestronk A, Teasley J, Bertorini TE, Webster R, Kolski H, Kuntz N, Driscoll S, Bodensteiner JB, Gorni K, Lotze T, Day JW, Karachunski P, Henricson EK, Joyce NC, McDonald CM, Campbell C, Torricelli RE, Finkel RS, Flanigan KM, Goemans N, Heydemann P, Kaminska A, Kirschner J, Muntoni F, Osorio AN, Schara U, Sejersen T, Shieh PB, Sweeney HL, Topaloglu H, Tulinius M, Vilchez JJ, Voit T, Wong B, Alfano LN, Eagle M, James MK, Lowes L, Mayhew A, Mazzone ES, Nelson L, Rose KJ, Abdel-Hamid HZ, Apkon SD, Barohn RJ, Bertini E, Bloetzer C, deVaud LC, Butterfield RJ, Chabrol B, Chae JH, Comi GP, Darras BT, Dastgir J, Desguerre I, Escobar RG, Finanger E, Guglieri M, Hughes I et al. Towards regulatory endorsement of drug development tools to promote the application of model-informed drug development in duchenne muscular dystrophy. Journal of Pharmacokinetics and Pharmacodynamics 2019;46:441–55.

Prat LI, Wilson P, Freeman SC, Sutton AJ, Cooper NJ, Roccarina D, Benmassaoud A, Plaz Torres MC, Hawkins N, Cowlin M, Milne EJ, Thorburn D, Pavlov CS, Davidson BR, Tsochatzis E, Gurusamy KS. Antibiotic treatment for spontaneous bacterial peritonitis in people with decompensated liver cirrhosis: A network meta-analysis. Cochrane Database of Systematic Reviews 2019;2019:

Best LM, Freeman SC, Sutton AJ, Cooper NJ, Tng E-L, Csenar M, Hawkins N, Pavlov CS, Davidson BR, Thorburn D, Cowlin M, Janemilne E, Tsochatzis E, Gurusamy KS. Treatment for hepatorenal syndrome in people with decompensated liver cirrhosis: A network meta-analysis. Cochrane Database of Systematic Reviews 2019;2019:

Harhay MO, Ratcliffe SJ, Small DS, Suttner LH, Crowther MJ, Halpern SD. Measuring and analyzing length of stay in critical care trials. Medical Care 2019;57:E53–9. .

Seaton SE, Draper ES, Abrams KR, Modi N, Manktelow BN. Can we estimate the length of stay of very preterm multiples? Archives of Disease in Childhood: Fetal and Neonatal Edition 2019;104:F568–70.

Weibull CE, Björkholm M, Glimelius I, Lambert PC, Andersson TM, Smedby KE, Dickman PW, Eloranta S. Temporal trends in treatment-related incidence of diseases of the circulatory system among hodgkin lymphoma patients. International Journal of Cancer 2019;145:1200–8.

Houghton JS, Nduwayo S, Nickinson AT, Payne TJ, Sterland S, Nath M, Gray LJ, McMahon GS, Rayt HS, Singh SJ, Robinson TG, Conroy SP, Haunton VJ, McCann GP, Bown MJ, Davies RS, Sayers RD. Leg ischaemia management collaboration (limb): Study protocol for a prospective cohort study at a single uk centre. BMJ Open 2019;9: 

Bujkiewicz S, Jackson D, Thompson JR, Turner RM, Städler N, Abrams KR, White IR. Bivariate network meta-analysis for surrogate endpoint evaluation. Statistics in Medicine 2019;38:3322–41.

Latimer NR, White IR, Abrams KR, Siebert U. Causal inference for long-term survival in randomised trials with treatment switching: Should re-censoring be applied when estimating counterfactual survival times? Statistical Methods in Medical Research 2019;28:2475–93. 

Dam V, Van Der Schouw YT, Onland-Moret NC, Groenwold RH, Peters SA, Burgess S, Wood AM, Chirlaque M-D, Moons KG, Oliver-Williams C, Schuit E, Tikk K, Weiderpass E, Holm M, Tjønneland A, Kühn T, Fortner RT, Trichopoulou A, Karakatsani A, La Vecchia C, Ferrari P, Gunter M, Masala G, Sieri S, Tumino R, Panico S, Boer JM, Monique Verschuren WM, Salamanca-Fernández E, Arriola L, Moreno-Iribas C, Engström G, Melander O, Nordendahl M, Wennberg P, Key TJ, Colorado-Yohar S, Matullo G, Overvad K, Clavel-Chapelon F, Boeing H, Ramon Quiros J, Di Angelantonio E, Langenberg C, Sweeting MJ, Riboli E, Wareham NJ, Danesh J, Butterworth A. Association of menopausal characteristics and risk of coronary heart disease: A pan-european case-cohort analysis. International Journal of Epidemiology 2019;48:1275–85.

Gray LJ, Brady EM, Albaina O, Edwardson CL, Harrington D, Khunti K, Miksza J, Raposo JF, Smith E, Vazeou A, Vergara I, Weihrauch-Blüher S, Davies MJ, Enright S, Yates T, Surridge G, Amengual JM, De Manuel E, Iturralde MD, Ponce S, Erreguerena I, Mateo-Abad M, Perales A, Aizpuru G, Pfaeffle R, Grimm A, Ribeiro R, Karagiozoglou-Lampoudi T, Chatzipsalti VM, Charmandari E, Apostolou A, Kassari P, Kouloufakou-Gratsia K, Papadimitriou E, Michalakis K, Wilmot E, Greening J, Castro SV, Pina RM, Sundaram P, Zaccardi F, Alustiza E, Ozcoidi I, Fuentes S, Galhardo J, Mantzoros C, Wiegand S. Evaluation and refinement of the prestart tool for identifying 12-14 year olds at high lifetime risk of developing type 2 diabetes compared to a clinicians assessment of risk: A cross-sectional study. BMC Endocrine Disorders 2019;19:

Andersson TM-L, Rutherford MJ, Lambert PC. Illustration of different modelling assumptions for estimation of loss in expectation of life due to cancer. BMC Medical Research Methodology 2019;19:

Dunkley AJ, Fitzpatrick C, Gray LJ, Waheed G, Heller SR, Frier BM, Davies MJ, Khunti K. Incidence and severity of hypoglycaemia in type 2 diabetes by treatment regimen: A uk multisite 12-month prospective observational study. Diabetes, Obesity and Metabolism 2019;21:1585–95.

Key TJ, Appleby PN, Bradbury KE, Sweeting M, Wood A, Johansson I, Kühn T, Steur M, Weiderpass E, Wennberg M, Lund Würtz AM, Agudo A, Andersson J, Arriola L, Boeing H, Boer JM, Bonnet F, Boutron-Ruault M-C, Cross AJ, Ericson U, Fagherazzi G, Ferrari P, Gunter M, Huerta JM, Katzke V, Khaw K-T, Krogh V, La Vecchia C, Matullo G, Moreno-Iribas C, Naska A, Nilsson LM, Olsen A, Overvad K, Palli D, Panico S, Molina-Portillo E, Quirós JR, Skeie G, Sluijs I, Sonestedt E, Stepien M, Tjønneland A, Trichopoulou A, Tumino R, Tzoulaki I, Van Der Schouw YT, Verschuren WM, Di Angelantonio E, Langenberg C, Forouhi N, Wareham N, Butterworth A, Riboli E, Danesh J. Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the pan-european epic cohort. Circulation 2019;139:2835–45.

Nikolakopoulou A, Trelle S, Sutton AJ, Egger M, Salanti G. Synthesizing existing evidence to design future trials: Survey of methodologists from european institutions. Trials 2019;20:

Rutherford MJ, Andersson TM-L, Björkholm M, Lambert PC. Loss in life expectancy and gain in life years as measures of cancer impact. Cancer Epidemiology 2019;60:168–73.

Bower H, Andersson TM-L, Syriopoulou E, Rutherford MJ, Lambe M, Ahlgren J, Dickman PW, Lambert PC. Potential gain in life years for swedish women with breast cancer if stage and survival differences between education groups could be eliminated – three what-if scenarios. Breast 2019;45:75–81.

Gillies CL, Farrukh A, Abrams KR, Mayberry JF. Risk of esophageal cancer in achalasia cardia: A meta-analysis. JGH Open 2019;3:196–200.

Saramago P, Espinoza MA, Sutton AJ, Manca A, Claxton K. The value of further research: The added value of individual-participant level data. Applied Health Economics and Health Policy 2019;17:273–84.

Syriopoulou E, Morris E, Finan PJ, Lambert PC, Rutherford MJ. Understanding the impact of socioeconomic differences in colorectal cancer survival: Potential gain in life-years. British Journal of Cancer 2019;120:1052–8.

Morris TP, White IR, Crowther MJ. Using simulation studies to evaluate statistical methods. Statistics in Medicine 2019;38:2074–102.

Freeman SC, Kerby CR, Patel A, Cooper NJ, Quinn T, Sutton AJ. Development of an interactive web-based tool to conduct and interrogate meta-analysis of diagnostic test accuracy studies: MetaDTA. BMC Medical Research Methodology 2019;19:

Burton JK, Siddiqi N, Teale EA, Barugh A, Sutton AJ. Non-pharmacological interventions for preventing delirium in hospitalised non-icu patients. Cochrane Database of Systematic Reviews 2019;2019:

Hussein H, Zaccardi F, Khunti K, Seidu S, Davies MJ, Gray LJ. Cardiovascular efficacy and safety of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: A systematic review and network meta-analysis. Diabetic Medicine 2019;36:444–52.

Latimer NR, Abrams KR, Siebert U. Two-stage estimation to adjust for treatment switching in randomised trials: A simulation study investigating the use of inverse probability weighting instead of re-censoring. BMC Medical Research Methodology 2019;19:

Oliver-Williams C, Sweeting MJ, Jacomelli J, Summers L, Stevenson A, Lees T, Earnshaw JJ. Safety of men with small and medium abdominal aortic aneurysms under surveillance in the naaasp. Circulation 2019;139:1371–80.

Hendry K, Green C, McShane R, Noel-Storr AH, Stott DJ, Anwer S, Sutton AJ, Burton JK, Quinn TJ. AD-8 for detection of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews 2019;2019:

Chung RK, Wood AM, Sweeting MJ. Biases incurred from nonrandom repeat testing of haemoglobin levels in blood donors: Selective testing and its implications. Biometrical Journal 2019;61:454–66.

Tyrer F, Dunkley AJ, Singh J, Kristunas C, Khunti K, Bhaumik S, Davies MJ, Yates TE, Gray LJ. Multimorbidity and lifestyle factors among adults with intellectual disabilities: A cross-sectional analysis of a uk cohort. Journal of Intellectual Disability Research 2019;63:255–65.

Harhay MO, Porcher R, Thabut G, Crowther MJ, DiSanto T, Rubin S, Penfil Z, Bing Z, Christie JD, Diamond JM, Cantu E. Donor lung sequence number and survival after lung transplantation in the united states. Annals of the American Thoracic Society 2019;16:313–20.

Krusche A, Bradbury K, Corbett T, Barnett J, Stuart B, Yao GL, Bacon R, Böhning D, Cheetham-Blake T, Eccles D, Foster C, Geraghty AW, Leydon G, Müller A, Neal RD, Osborne R, Rathod S, Richardson A, Sharman G, Summers K, Watson E, Wilde L, Wilkinson C, Yardley L, Little P. Renewed: Protocol for a randomised controlled trial of a digital intervention to support quality of life in cancer survivors. BMJ Open 2019;9:

Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, Burgess S, Willeit P, Bolton T, Moons KG, Van Der Schouw YT, Selmer R, Khaw K-T, Gudnason V, Assmann G, Amouyel P, Salomaa V, Kivimaki M, Nordestgaard B, Blaha MJ, Kuller LH, Brenner H, Gillum RF, Meisinger C, Ford I, Knuiman MW, Rosengren A, Lawlor DA, Völzke H, Cooper C, Marín Ibañez A, Casiglia E, Kauhanen J, Cooper JA, Rodriguez B, Sundström J, Barrett-Connor E, Dankner R, Nietert PJ, Davidson KW, Wallace RB, Blazer DG, Björkelund C, Donfrancesco C, Krumholz HM, Nissinen A, Davis BR, Coady S, Whincup PH, Jørgensen T, Ducimetiere P, Trevisan M, Engström G, Crespo CJ, Meade TW, Visser M, Kromhout D, Kiechl S, Daimon M, Price JF, Gómez De La Cámara A, Wouter Jukema J, Lamarche B, Onat A, Simons LA, Kavousi M, Ben-Shlomo Y, Gallacher J, Dekker JM, Arima H, Shara N, Tipping RW, Roussel R, Brunner EJ, Koenig W, Sakurai M, Pavlovic J, Gansevoort RT, Nagel D, Goldbourt U, Barr EL, Palmieri L, Njølstad I, Sato S, Monique Verschuren WM, Varghese CV, Graham I, Onuma O, Greenland P, Woodward M, Ezzati M, Psaty BM, Sattar N, Jackson R, Ridker PM, Cook NR, D’Agostino RB, Thompson SG, Danesh J et al. Equalization of four cardiovascular risk algorithms after systematic recalibration: Individual-participant meta-analysis of 86 prospective studies. European Heart Journal 2019;40:621–31. 

Syriopoulou E, Mozumder SI, Rutherford MJ, Lambert PC. Robustness of individual and marginal model-based estimates: A sensitivity analysis of flexible parametric models. Cancer Epidemiology 2019;58:17–24.

Wheeler GM, Sweeting MJ, Mander AP. A bayesian model-free approach to combination therapy phase i trials using censored time-to-toxicity data. Journal of the Royal Statistical Society Series C: Applied Statistics 2019;68:309–29.

Paige E, Clément M, Lareyre F, Sweeting M, Raffort J, Grenier C, Finigan A, Harrison J, Peters JE, Sun BB, Butterworth AS, Harrison SC, Bown MJ, Lindholt JS, Badger SA, Kullo IJ, Powell J, Norman PE, Scott DJ, Bailey MA, Rose-John S, Danesh J, Freitag DF, Paul DS, Mallat Z. Interleukin-6 receptor signaling and abdominal aortic aneurysm growth rates. Circulation: Genomic and Precision Medicine 2019;12:84–93.

Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P, Burgess S, Bell S, Sweeting M, Rimm EB, Kabrhel C, Zöller B, Assmann G, Gudnason V, Folsom AR, Arndt V, Fletcher A, Norman PE, Nordestgaard B, Kitamura A, Mahmoodi BK, Whincup PH, Knuiman M, Salomaa V, Meisinger C, Koenig W, Kavousi M, Völzke H, Cooper JA, Ninomiya T, Casiglia E, Rodriguez B, Ben-Shlomo Y, Després J-P, Simons L, Barrett-Connor E, Björkelund C, Notdurfter M, Kromhout D, Price J, Sutherland SE, Sundström J, Kauhanen J, Gallacher J, Beulens JW, Dankner R, Cooper C, Giampaoli S, Deen JF, Gómez De La Cámara A, Kuller LH, Rosengren A, Svensson PJ, Nagel D, Crespo CJ, Brenner H, Albertorio-Diaz JR, Atkins R, Brunner EJ, Shipley M, Njølstad I, Lawlor DA, Van Der Schouw YT, Selmer RM, Trevisan M, Verschuren WM, Greenland P, Wassertheil-Smoller S, Lowe GD, Wood AM, Butterworth AS, Thompson SG, Danesh J, Di Angelantonio E, Meade T. Cardiovascular risk factors associated with venous thromboembolism. JAMA Cardiology 2019;4:163–73. 

Kristunas CA, Hemming K, Eborall H, Eldridge S, Gray LJ. The current use of feasibility studies in the assessment of feasibility for stepped-wedge cluster randomised trials: A systematic review. BMC Medical Research Methodology 2019;19:

Adlam D, Olson TM, Combaret N, Kovacic JC, Iismaa SE, Al-Hussaini A, O’Byrne MM, Bouajila S, Georges A, Mishra K, Braund PS, d’Escamard V, Huang S, Margaritis M, Nelson CP, Andrade M de, Kadian-Dodov D, Welch CA, Mazurkiewicz S, Jeunemaitre X, Motreff P, Belle L, Dupouy P, Barnay P, Meneveau N, Gilard M, Rioufol G, Range G, Brunel P, Delarche N, Filippi E, Le Bivic L, Harbaoui B, Benamer H, Cayla G, Varenne O, Manzo-Silberman SP, Silvain J, Spaulding C, Caussin C, Gerbaud E, Valy Y, Koning R, Lhermusier T, Champin S, Salengro E, Fluttaz A, Zabalawi A, Cottin Y, Teiger E, Saint-Etienne C, Ducrocq G, Marliere S, Boiffard E, Aubry P, Georges JL, Bresson D, De Poli F, Karrillon G, Roule V, Bali L, Valla M, Gerbay A, Houpe D, Dubreuil O, Monnier A, Mayaud N, Manchuelle A, Commeau P, Bedossa M, Wong CM, Giannoulatou E, Sweeting M, Muller D, Wood A, McGrath-Cadell L, Fatkin D, Dunwoodie SL, Harvey R, Holloway C, Empana J-P, Jouven X, Nikpay M, Goel A, Won H-H, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Hopewell JC, Webb TR, Zeng L, Dehghan A, Alver M, Armasu SM, Auro K, Bjonnes A, Chasman DI et al. Association of the phactr1/edn1 genetic locus with spontaneous coronary artery dissection. Journal of the American College of Cardiology 2019;73:58–66.

Owen RK, Bradbury N, Xin Y, Cooper N, Sutton A. MetaInsight: An interactive web-based tool for analyzing, interrogating, and visualizing network meta-analyses using r-shiny and netmeta. Research Synthesis Methods 2019.

Gasparini A, Abrams KR, Barrett JK, Major RW, Sweeting MJ, Brunskill NJ, Crowther MJ. Mixed-effects models for health care longitudinal data with an informative visiting process: A monte carlo simulation study. Statistica Neerlandica 2019.

Bower H, Crowther MJ, Rutherford MJ, Andersson TM-L, Clements M, Liu X-R, Dickman PW, Lambert PC. Capturing simple and complex time-dependent effects using flexible parametric survival models: A simulation study. Communications in Statistics: Simulation and Computation 2019.

Brilleman SL, Moreno-Betancur M, Polkinghorne KR, McDonald SP, Crowther MJ, Thomson J, Wolfe R. Changes in body mass index and rates of death and transplant in hemodialysis patients: A latent class joint modeling approach. Epidemiology 2019;30:38–47.

Lalu MM, Fergusson DA, Cheng W, Avey MT, Corbett D, Dowlatshahi D, Macleod MR, Sena ES, Moher D, Shorr R, McCann SK, Gray LJ, Hill MD, O’Connor A, Thayer K, Haggar F, Dobriyal A, Chung HS, Welton NJ, Hutton B. Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis [version 1; referees: 2 approved]. F1000Research 2019;8:

Coombes RC, Page K, Salari R, Hastings RK, Armstrong A, Ahmed S, Ali S, Cleator S, Kenny L, Stebbing J, Rutherford M, Sethi H, Boydell A, Swenerton R, Fernandez-Garcia D, Gleason KL, Goddard K, Guttery DS, Assaf ZJ, Wu H-T, Natarajan P, Moore DA, Primrose L, Dashner S, Tin AS, Balcioglu M, Srinivasan R, Shchegrova SV, Olson A, Hafez D, Billings P, Aleshin A, Rehman F, Toghill BJ, Hills A, Louie MC, Lin C-H, Zimmermann BG, Shaw JA. Personalized detection of circulating tumor dna antedates breast cancer metastatic recurrence. Clinical Cancer Research 2019;25:4255–63.

Jones HE, Ades AE, Sutton AJ, Welton NJ. Use of a random effects meta-analysis in the design and analysis of a new clinical trial. Statistics in Medicine 2018;37:4665–79.

Sukumar N, Dallosso H, Saravanan P, Yates T, Telling C, Shorthose K, Northern A, Schreder S, Brough C, Gray LJ, Davies MJ, Khunti K. Baby steps - a structured group education programme with accompanying mobile web application designed to promote physical activity in women with a history of gestational diabetes: Study protocol for a randomised controlled trial. Trials 2018;19:

Archer DP, McCann SK, Walker AM, Premji ZA, Rogan KJ, Hutton MJ, Gray LJ. Neuroprotection by anaesthetics in rodent models of traumatic brain injury: A systematic review and network meta-analysis. British Journal of Anaesthesia 2018;121:1272–81.

Hussein H, Zaccardi F, Dhalwani NN, Davies MJ, Khunti K, Gray LJ. Efficacy and safety of sodium-glucose cotransporter 2 inhibitors (sglt-2is) and glucagon-like peptide-1 receptor agonists (glp-1RAs) in patients with type 2 diabetes: A systematic review and network meta-analysis study protocol. BMJ Open 2018;8:

Byrne JL, Dallosso HM, Rogers S, Gray LJ, Waheed G, Patel P, Gupta P, Doherty Y, Davies M, Khunti K. Erratum: Addendum to the acknowledgements, table 1, and references: The ready to reduce risk (3R) study for a group educational intervention with telephone and text messaging support to improve medication adherence for the primary prevention of cardiovascular disease: Protocol for a randomized controlled trial (jmir res protoc (2019) 8:7 (e13831) doi: 10.2196/11289). Journal of Medical Internet Research 2018;21:

Dallosso H, Yates T, Mani H, Gray LJ, Dhalwani N, Baldry E, Gillies C, Cradock S, Batt M, Davies MJ, Khunti K. Movement through active personalised engagement (map) - a self-management programme designed to promote physical activity in people with multimorbidity: Study protocol for a randomised controlled trial. Trials 2018;19:

Liu Z, Dumville JC, Hinchliffe RJ, Cullum N, Game F, Stubbs N, Sweeting M, Peinemann F. Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus. Cochrane Database of Systematic Reviews 2018;2018:

Inouye M, Abraham G, Nelson CP, Wood AM, Sweeting MJ, Dudbridge F, Lai FY, Kaptoge S, Brozynska M, Wang T, Ye S, Webb TR, Rutter MK, Tzoulaki I, Patel RS, Loos RJ, Keavney B, Hemingway H, Thompson J, Watkins H, Deloukas P, Di Angelantonio E, Butterworth AS, Danesh J, Samani NJ. Genomic risk prediction of coronary artery disease in 480,000 adults: Implications for primary prevention. Journal of the American College of Cardiology 2018;72:1883–93. 

Tan SH, Abrams KR, Bujkiewicz S. Bayesian multiparameter evidence synthesis to inform decision making: A case study in metastatic hormone-refractory prostate cancer. Medical Decision Making 2018;38:834–48.

Mozumder SI, Dickman PW, Rutherford MJ, Lambert PC. InterPreT cancer survival: A dynamic web interactive prediction cancer survival tool for health-care professionals and cancer epidemiologists. Cancer Epidemiology 2018;56:46–52.

Sargeant JA, Gray LJ, Bodicoat DH, Willis SA, Stensel DJ, Nimmo MA, Aithal GP, King JA. The effect of exercise training on intrahepatic triglyceride and hepatic insulin sensitivity: A systematic review and meta-analysis. Obesity Reviews 2018;19:1446–59.

Edwardson CL, Biddle SJ, Clarke-Cornwell A, Clemes S, Davies MJ, Dunstan DW, Eborall H, Granat MH, Gray LJ, Healy GN, Richardson G, Yates T, Munir F. A three arm cluster randomised controlled trial to test the effectiveness and cost-effectiveness of the smart work & life intervention for reducing daily sitting time in office workers: Study protocol 11 medical and health sciences 1117 public health and health services. BMC Public Health 2018;18: 

Weibull CE, Johansson AL, Eloranta S, Smedby KE, Björkholm M, Lambert PC, Dickman PW, Glimelius I. Contemporarily treated patients with hodgkin lymphoma have childbearing potential in line with matched comparators. Journal of Clinical Oncology 2018;36:2718–25.

Best LM, Freeman S, Sutton AJ, Hawkins N, Tsochatzis E, Gurusamy KS. Treatment for hepatorenal syndrome in people with decompensated liver cirrhosis: A network meta-analysis. Cochrane Database of Systematic Reviews 2018;2018: 

Harhay MO, Porcher R, Cantu E, Crowther MJ, Christie JD, Thabut G, Donaldson GC. An alternative approach for the analysis of time-to-event and survival outcomes in pulmonary medicine. American Journal of Respiratory and Critical Care Medicine 2018;198:684–7.

Grootes I, Barrett JK, Ulug P, Rohlffs F, Laukontaus SJ, Tulamo R, Venermo M, Greenhalgh RM, Sweeting MJ. Predicting risk of rupture and rupture-preventing reinterventions following endovascular abdominal aortic aneurysm repair. British Journal of Surgery 2018;105:1294–304.

Martina R, Jenkins D, Bujkiewicz S, Dequen P, Abrams K. The inclusion of real world evidence in clinical development planning. Trials 2018;19: 

Sweeting MJ, Masconi KL, Jones E, Ulug P, Glover MJ, Michaels JA, Bown MJ, Powell JT, Thompson SG. Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm. The Lancet 2018;392:487–95. https://doi.org/10.1016/S0140-6736(18)31222-4.Thompson SG, Bown MJ, Glover MJ, Jones E, Masconi KL, Michaels JA, Powell JT, Ulug P, Sweeting MJ. Screening women aged 65 years or over for abdominal aortic aneurysm: A modelling study and health economic evaluation. Health Technology Assessment 2018;22:V–141.

Sweeting MJ, Ulug P, Roy J, Hultgren R, Indrakusuma R, Balm R, Thompson MM, Hinchliffe RJ, Thompson SG, Powell JT, Balm R, Koelemay MJ, Idu MM, Kox C, Legemate DA, Huisman LC, Willems MC, Reekers JA, Delden OM van, Lienden KP van, Hoornweg LL, Reimerink JJ, Beek SC van, Vahl AC, Leijdekkers VJ, Bosma J, Montauban van Swijndregt AD, Vries C de, Hulst VP van der, Peringa J, Blomjous JGM, Visser MJ, Heijden FHM van der, Wisselink W, Hoksbergen AW, Blankensteijn JD, Visser MT, Coveliers HM, Nederhoed JH, Berg FG van den, Meijs BB van der, Oever ML van den, Lely RJ, Meijerink MR, Westra I, Voorwinde A, Ultee JM, Nieuwenhuizen RC van, Dwars BJ, Nagy TO, Tolenaar P, Wiersema AM, Lawson JA, Aken PJ van, Stigter AA, Broek TA van den, Vos GA, Mulder W, Strating RP, Nio D, Akkersdijk GJ, Elst A van der, Exter P van, Desgranges P, Becquemin J-P, Allaire E, Cochennec F, Marzelle J, Louis N, Schneider J, Majewski M, Castier Y, Leseche G, Francis F, Steinmetz E, Berne J-P, Favier C, Haulon S, Koussa M, Azzaoui R, Piervito D, Alimi Y, Boufi M, Hartung O, Cerquetta P, Amabile P, Piquet P, Penard J, Demasi M, Alric P, Cannaud L, Berthet J-P, Julia P, Fabiani J-N, Alsac JM, Gouny P, Badra A, Braesco J, Favre J-P et al. Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm. British Journal of Surgery 2018;105:1135–44.

Salanti G, Nikolakopoulou A, Sutton AJ, Reichenbach S, Trelle S, Naci H, Egger M. Planning a future randomized clinical trial based on a network of relevant past trials. Trials 2018;19:

Owen RK, Cooper NJ, Quinn TJ, Lees R, Sutton AJ. Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making. Journal of Clinical Epidemiology 2018;99:64–74.

Zemedikun DT, Gray LJ, Khunti K, Davies MJ, Dhalwani NN. Patterns of multimorbidity in middle-aged and older adults: An analysis of the uk biobank data. Mayo Clinic Proceedings 2018;93:857–66.

Salmasi MY, Harky A, Chowdhury MF, Abdelnour A, Benjafield A, Suker F, Hubbard S, Vohra HA. Should the mitral valve be repaired for moderate ischemic mitral regurgitation at the time of revascularization surgery? Journal of Cardiac Surgery 2018;33:374–84. 

Paige E, Barrett J, Stevens D, Keogh RH, Sweeting MJ, Nazareth I, Petersen I, Wood AM. Landmark models for optimizing the use of repeated measurements of risk factors in electronic health records to predict future disease risk. American Journal of Epidemiology 2018;187:1530–8.

Freeman SC, Scott NW, Powell R, Johnston M, Sutton AJ, Cooper NJ. Component network meta-analysis identifies the most effective components of psychological preparation for adults undergoing surgery under general anesthesia. Journal of Clinical Epidemiology 2018;98:105–16.

Jackson D, Bujkiewicz S, Law M, Riley RD, White IR. A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects. Biometrics 2018;74:548–56.

Willis A, Crasto W, Gray L, Dallosso H, Waheed G, Gray G, Davies MJ, Khunti K. The general practitioner prompt study to reduce cardiovascular and renal complications in patients with type 2 diabetes and renal complications: Protocol and baseline characteristics for a cluster randomized controlled trial. Journal of Medical Internet Research 2018;20: 

Li J, Parrott S, Sweeting M, Farmer A, Ross J, Dack C, Pal K, Yardley L, Barnard M, Hudda M, Alkhaldi G, Murray E. Cost-effectiveness of facilitated access to a self-management website, compared to usual care, for patients with type 2 diabetes (help-diabetes): Randomized controlled trial. Journal of Medical Internet Research 2018;20: 

Sonuga-Barke EJ, Barton J, Daley D, Hutchings J, Maishman T, Raftery J, Stanton L, Laver-Bradbury C, Chorozoglou M, Coghill D, Little L, Ruddock M, Radford M, Yao GL, Lee L, Gould L, Shipway L, Markomichali P, McGuirk J, Lowe M, Perez E, Lockwood J, Thompson MJ. A comparison of the clinical effectiveness and cost of specialised individually delivered parent training for preschool attention-deficit/hyperactivity disorder and a generic, group-based programme: A multi-centre, randomised controlled trial of the new forest parenting programme versus incredible years. European Child and Adolescent Psychiatry 2018;27:797–809.

Powell JT, Sweeting MJ, Ulug P, Thompson MM, Hinchliffe RJ. Editor’s choice – re-interventions after repair of ruptured abdominal aortic aneurysm: A report from the improve randomised trial. European Journal of Vascular and Endovascular Surgery 2018;55:625–32.

Glover MJ, Jones E, Masconi KL, Sweeting MJ, Thompson SG, Powell JT, Ulug P, Bown MJ. Discrete event simulation for decision modeling in health care: Lessons from abdominal aortic aneurysm screening. Medical Decision Making 2018;38:439–51.

Ulug P, Hinchliffe RJ, Sweeting MJ, Gomes M, Thompson MT, Thompson SG, Grieve RJ, Ashleigh R, Greenhalgh RM, Powell JT. Strategy of endovascular versus open repair for patients with clinical diagnosis of ruptured abdominal aortic aneurysm: The improve rct. Health Technology Assessment 2018;22:1–122.

Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Bolton T, Paige E, Paul DS, Sweeting M, Burgess S, Bell S, Astle W, Stevens D, Koulman A, Selmer RM, Verschuren WM, Sato S, Njølstad I, Woodward M, Salomaa V, Nordestgaard BG, Yeap BB, Fletcher A, Melander O, Kuller LH, Balkau B, Marmot M, Koenig W, Casiglia E, Cooper C, Arndt V, Franco OH, Wennberg P, Gallacher J, Cámara AG de la, Völzke H, Dahm CC, Dale CE, Bergmann MM, Crespo CJ, Schouw YT van der, Kaaks R, Simons LA, Lagiou P, Schoufour JD, Boer JM, Key TJ, Rodriguez B, Moreno-Iribas C, Davidson KW, Taylor JO, Sacerdote C, Wallace RB, Quiros JR, Tumino R, Blazer DG, Linneberg A, Daimon M, Panico S, Howard B, Skeie G, Strandberg T, Weiderpass E, Psaty BM, Kromhout D, Salamanca-Fernandez E, Kiechl S, Krumholz HM, Grioni S, Palli D, Huerta JM, Price J, Sundström J, Arriola L, Arima H, Travis RC, Panagiotakos DB, Karakatsani A, Trichopoulou A, Kühn T, Grobbee DE, Barrett-Connor E, Schoor N van, Boeing H, Overvad K, Kauhanen J, Wareham N, Langenberg C, Forouhi N, Wennberg M, Després J-P, Cushman M, Cooper JA, Rodriguez CJ, Sakurai M, Shaw JE, Knuiman M, Voortman T, Meisinger C et al. Risk thresholds for alcohol consumption: Combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. The Lancet 2018;391:1513–23.

Bower H, Andersson TM-L, Crowther MJ, Dickman PW, Lambe M, Lambert PC. Adjusting expected mortality rates using information from a control population: An example using socioeconomic status. American Journal of Epidemiology 2018;187:828–36.

Seaton SE, Barker L, Draper ES, Abrams KR, Modi N, Manktelow BN. Estimating neonatal length of stay for babies born very preterm. Archives of Disease in Childhood: Fetal and Neonatal Edition 2018.

Plym A, Bower H, Fredriksson I, Holmberg L, Lambert PC, Lambe M. Loss in working years after a breast cancer diagnosis. British Journal of Cancer 2018;118:738–43. 

Munir F, Biddle SJ, Davies MJ, Dunstan D, Esliger D, Gray LJ, Jackson BR, O’Connell SE, Yates T, Edwardson CL. Stand more at work (smart work): Using the behaviour change wheel to develop an intervention to reduce sitting time in the workplace. BMC Public Health 2018;18:

Toghill BJ, Saratzis A, Freeman PJ, Sylvius N, Bown MJ, Pathak R, Brooks MJ, Hayes P, Imray CH, Quarmby J, Choksy SA, Earnshaw JJ, Shearman CP, Grocott E, Rix T, Chetter IC, Tennant W, Libertiny G, Sykes T, Dayer M, Pike L, Pherwani A, Nice C, Browning N, McCollum CN, Yusuf SW, Gannon M, Barwell J, Baker S, Vallabhaneni SR, Smyth JV, Davies AH, Lees T, Fligelstone L, Sayers R, Samani NJ, Sweeting MJ, Thompson J. SMYD2 promoter dna methylation is associated with abdominal aortic aneurysm (aaa) and smyd2 expression in vascular smooth muscle cells. Clinical Epigenetics 2018;10:

Latimer NR, Abrams KR, Lambert PC, Morden JP, Crowther MJ. Assessing methods for dealing with treatment switching in clinical trials: A follow-up simulation study. Statistical Methods in Medical Research 2018;27:765–84.

Major RW, Cheng MR, Grant RA, Shantikumar S, Xu G, Oozeerally I, Brunskill NJ, Gray LJ. Cardiovascular disease risk factors in chronic kidney disease: A systematic review and meta-analysis. PLoS ONE 2018;13:

Burke DL, Bujkiewicz S, Riley RD. Bayesian bivariate meta-analysis of correlated effects: Impact of the prior distributions on the between-study correlation, borrowing of strength, and joint inferences. Statistical Methods in Medical Research 2018;27:428–50.

Phillippo DM, Ades AE, Dias S, Palmer S, Abrams KR, Welton NJ. Methods for population-adjusted indirect comparisons in health technology appraisal. Medical Decision Making 2018;38:200–11.

Lassale C, Tzoulaki I, Moons KG, Sweeting M, Boer J, Johnson L, Huerta JM, Agnoli C, Freisling H, Weiderpass E, Wennberg P, Van Der A DL, Arriola L, Benetou V, Boeing H, Bonnet F, Colorado-Yohar SM, Engström G, Eriksen AK, Ferrari P, Grioni S, Johansson M, Kaaks R, Katsoulis M, Katzke V, Key TJ, Matullo G, Melander O, Molina-Portillo E, Moreno-Iribas C, Norberg M, Overvad K, Panico S, Quiros JR, Saieva C, Skeie G, Steffen A, Stepien M, Tjønneland A, Trichopoulou A, Tumino R, Van Der Schouw YT, Verschuren WM, Langenberg C, Di Angelantonio E, Riboli E, Wareham NJ, Danesh J, Butterworth AS. Separate and combined associations of obesity and metabolic health with coronary heart disease: A pan-european case-cohort analysis. European Heart Journal 2018;39:397–406.

Mozumder SI, Rutherford M, Lambert P. Direct likelihood inference on the cause-specific cumulative incidence function: A flexible parametric regression modelling approach. Statistics in Medicine 2018;37:82–97.

Bennett I, Paracha N, Abrams K, Ray J. Accounting for uncertainty in decision analytic models using rank preserving structural failure time modeling: Application to parametric survival models. Value in Health 2018;21:105–9.

Doleman B, Sutton AJ, Sherwin M, Lund JN, Williams JP. Baseline morphine consumption may explain between-study heterogeneity in meta-analyses of adjuvant analgesics and improve precision and accuracy of effect estimates. Anesthesia and Analgesia 2018;126:648–60.

Patel R, Powell JT, Sweeting MJ, Epstein DM, Barrett JK, Greenhalgh RM. The uk endovascular aneurysm repair (evar) randomised controlled trials: Long-term follow-up and cost-effectiveness analysis. Health Technology Assessment 2018;22:

Oliver-Williams C, Sweeting MJ, Turton G, Parkin D, Cooper D, Rodd C, Thompson SG, Earnshaw JJ. Lessons learned about prevalence and growth rates of abdominal aortic aneurysms from a 25-year ultrasound population screening programme. British Journal of Surgery 2018;105:68–74.

Mani H, Chudasama Y, Hadjiconstantinou M, Bodicoat DH, Edwardson C, Levy MJ, Gray LJ, Barnett J, Daly H, Howlett TA, Khunti K, Davies MJ. Structured education programme for women with polycystic ovary syndrome: A randomised controlled trial. Endocrine Connections 2018;7:26–35.

Bruton A, Lee A, Yardley L, Raftery J, Arden-Close E, Kirby S, Zhu S, Thiruvothiyur M, Webley F, Taylor L, Gibson D, Yao G, Stafford-Watson M, Versnel J, Moore M, George S, Little P, Djukanovic R, Price D, Pavord ID, Holgate ST, Thomas M. Physiotherapy breathing retraining for asthma: A randomised controlled trial. The Lancet Respiratory Medicine 2018;6:19–28.

Ricci C, Wood A, Muller D, Gunter MJ, Agudo A, Boeing H, Van Der Schouw YT, Warnakula S, Saieva C, Spijkerman A, Sluijs I, Tjønneland A, Kyrø C, Weiderpass E, Kühn T, Kaaks R, Sánchez M-J, Panico S, Agnoli C, Palli D, Tumino R, Engström G, Melander O, Bonnet F, Boer JM, Key TJ, Travis RC, Overvad K, Verschuren WM, Quirós JR, Trichopoulou A, Papatesta E-M, Peppa E, Iribas CM, Gavrila D, Forslund A-S, Jansson J-H, Matullo G, Arriola L, Freisling H, Lassale C, Tzoulaki I, Sharp SJ, Forouhi NG, Langenberg C, Saracci R, Sweeting M, Brennan P, Butterworth AS, Riboli E, Wareham NJ, Danesh J, Ferrari P. Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-cvd case-cohort study. BMJ (Online) 2018;361:

Crowther MJ, Lambert PC. Parametric multistate survival models: Flexible modelling allowing transition-specific distributions with application to estimating clinically useful measures of effect differences. Statistics in Medicine 2017;36:4719–42.

Sweeting MJ, Barrett JK, Thompson SG, Wood AM. The use of repeated blood pressure measures for cardiovascular risk prediction: A comparison of statistical models in the aric study. Statistics in Medicine 2017;36:4514–28.

Alabas OA, Gale CP, Hall M, Rutherford MJ, Szummer K, Lawesson SS, Alfredsson J, Lindahl B, Jernberg T. Sex differences in treatments, relative survival, and excess mortality following acute myocardial infarction: National cohort study using the swedeheart registry. Journal of the American Heart Association 2017;6:

Jelleyman C, Edwardson CL, Henson J, Gray LJ, Rowlands AV, Khunti K, Davies MJ, Yates T. Associations of physical activity intensities with markers of insulin sensitivity. Medicine and Science in Sports and Exercise 2017;49:2451–8.

Ellis M, Hall A, Hardman J, Mehta N, Nankiwell P, Sharma N, Smith ME, Williams RJ, Adams W, Carrie S, Cathcart R, Chatrath P, Hopkins C, Lenthall R, Mainwaring J, Nix P, Nokes T, Philpott C, Reuben A, Salib R, Sura P, Sutton A, Ward V, White P. The british rhinological society multidisciplinary consensus recommendations on the hospital management of epistaxis. Journal of Laryngology and Otology 2017;131:1142–56.

Sweeting MJ. Using predictions from a joint model for longitudinal and survival data to inform the optimal time of intervention in an abdominal aortic aneurysm screening programme. Biometrical Journal 2017;59:1247–60.

Sutton AJ. Not enough i say! Expand the remit of living systematic reviews to inform future research. Journal of Clinical Epidemiology 2017;91:54–5.

Kristunas C, Morris T, Gray L. Unequal cluster sizes in stepped-wedge cluster randomised trials: A systematic review. BMJ Open 2017;7: 

Sweeting MJ, Patel R, Powell JT, Greenhalgh RM. Endovascular repair of abdominal aortic aneurysm in patients physically ineligible for open repair. Annals of Surgery 2017;266:713–9.

Andersson TM-L, Crowther MJ, Czene K, Hall P, Humphreys K. Mammographic density reduction as a prognostic marker for postmenopausal breast cancer: Results using a joint longitudinal-survival modeling approach. American Journal of Epidemiology 2017;186:1065–73.

Barber SR, Dhalwani NN, Davies MJ, Khunti K, Gray LJ. External national validation of the leicester self-assessment score for type 2 diabetes using data from the english longitudinal study of ageing. Diabetic Medicine 2017;34:1575–83.

Paige E, Barrett J, Pennells L, Sweeting M, Willeit P, Di Angelantonio E, Gudnason V, Nordestgaard BG, Psaty BM, Goldbourt U, Best LG, Assmann G, Salonen JT, Nietert PJ, Verschuren WM, Brunner EJ, Kronmal RA, Salomaa V, Bakker SJ, Dagenais GR, Sato S, Jansson J-H, Willeit J, Onat A, De La Cámara AG, Roussel R, Völzke H, Dankner R, Tipping RW, Meade TW, Donfrancesco C, Kuller LH, Peters A, Gallacher J, Kromhout D, Iso H, Knuiman M, Casiglia E, Kavousi M, Palmieri L, Sundström J, Davis BR, Njølstad I, Couper D, Danesh J, Thompson SG, Wood A. Use of repeated blood pressure and cholesterol measurements to improve cardiovascular disease risk prediction: An individual-participant-data meta-analysis. American Journal of Epidemiology 2017;186:899–907.

Powell JT, Ulug P, Sweeting MJ, Allmen RS von, Thompson SG. Abdominal aortic aneurysms in women – authors’ reply. The Lancet 2017;390:1643–4.

Bujkiewicz S, Thompson JR, Spata E, Abrams KR. Uncertainty in the bayesian meta-analysis of normally distributed surrogate endpoints. Statistical Methods in Medical Research 2017;26:2287–318.

Trivedi H, Gray LJ, Seidu S, Davies MJ, Charpentier G, Lindblad U, Kellner C, Nolan J, Pazderska A, Rutten G, Trento M, Khunti K. Self-knowledge of hba1c in people with type 2 diabetes mellitus and its association with glycaemic control. Primary Care Diabetes 2017;11:414–20.

Marriott L, Zinaman M, Abrams KR, Crowther MJ, Johnson S. Analysis of urinary human chorionic gonadotrophin concentrations in normal and failing pregnancies using longitudinal, cox proportional hazards and two-stage modelling. Annals of Clinical Biochemistry 2017;54:548–57. 

Murray E, Sweeting M, Dack C, Pal K, Modrow K, Hudda M, Li J, Ross J, Alkhaldi G, Barnard M, Farmer A, Michie S, Yardley L, May C, Parrott S, Stevenson F, Knox M, Patterson D. Web-based self-management support for people with type 2 diabetes (helpdiabetes): Randomised controlled trial in english primary care. BMJ Open 2017;7: 

Thomas M, Bruton A, Little P, Holgate S, Lee A, Yardley L, George S, Raftery J, Versnel J, Price D, Pavord I, Djukanovic R, Moore M, Kirby S, Yao G, Zhu S, Arden-Close E, Thiruvothiyur M, Webley F, Stafford-Watson M, Dixon E, Taylor L. A randomised controlled study of the effectiveness of breathing retraining exercises taught by a physiotherapist either by instructional dvd or in face-to-face sessions in the management of asthma in adults. Health Technology Assessment 2017;21:1–161.

Nelson CP, Goel A, Butterworth AS, Kanoni S, Webb TR, Marouli E, Zeng L, Ntalla I, Lai FY, Hopewell JC, Giannakopoulou O, Jiang T, Hamby SE, Di Angelantonio E, Assimes TL, Bottinger EP, Chambers JC, Clarke R, Palmer CN, Cubbon RM, Ellinor P, Ermel R, Evangelou E, Franks PW, Grace C, Gu D, Hingorani AD, Howson JM, Ingelsson E, Kastrati A, Kessler T, Kyriakou T, Lehtimäki T, Lu X, Lu Y, März W, McPherson R, Metspalu A, Pujades-Rodriguez M, Ruusalepp A, Schadt EE, Schmidt AF, Sweeting MJ, Zalloua PA, Alghalayini K, Keavney BD, Kooner JS, Loos RJ, Patel RS, Rutter MK, Tomaszewski M, Tzoulaki I, Zeggini E, Erdmann J, Dedoussis G, Björkegren JL, Schunkert H, Farrall M, Danesh J, Samani NJ, Watkins H, Deloukas P. Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nature Genetics 2017;49:1385–91. 

Sayers A, Crowther MJ, Judge A, Whitehouse MR, Blom AW. Determining the sample size required to establish whether a medical device is non-inferior to an external benchmark. BMJ Open 2017;7:

Wheeler GM, Sweeting MJ, Mander AP. Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase i cancer trials. Statistics in Medicine 2017;36:2499–513. 

Peters TL, Weibull CE, Fang F, Sandler DP, Lambert PC, Ye W, Kamel F. Association of fractures with the incidence of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2017;18:419–25.

Dunkley AJ, Tyrer F, Gray LJ, Bhaumik S, Spong R, Chudasama Y, Cooper S-A, Ganghadaran S, Davies M, Khunti K. Type 2 diabetes and glucose intolerance in a population with intellectual disabilities: The stop diabetes cross-sectional screening study. Journal of Intellectual Disability Research 2017;61:668–81.

Ulug P, Sweeting MJ, Allmen RS von, Thompson SG, Powell JT, Ulug P, Sweeting MJ, Thompson SG, Powell JT, Jones E, Bown MJ, Glover MJ, Michaels J. Morphological suitability for endovascular repair, non-intervention rates, and operative mortality in women and men assessed for intact abdominal aortic aneurysm repair: Systematic reviews with meta-analysis. The Lancet 2017;389:2482–91.

Batson S, Score R, Sutton AJ. Three-dimensional evidence network plot system: Covariate imbalances and effects in network meta-analysis explored using a new software tool. Journal of Clinical Epidemiology 2017;86:182–95.

Staley JR, Jones E, Kaptoge S, Butterworth AS, Sweeting MJ, Wood AM, Howson JM. A comparison of cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design. European Journal of Human Genetics 2017;25:854–62.

Kidy FF, Dhalwani N, Harrington DM, Gray LJ, Bodicoat DH, Webb D, Davies MJ, Khunti K. Associations between anthropometric measurements and cardiometabolic risk factors in white european and south asian adults in the united kingdom. Mayo Clinic Proceedings 2017;92:925–33.

Zaccardi F, Webb DR, Davies MJ, Dhalwani NN, Gray LJ, Chatterjee S, Housley G, Shaw D, Hatton JW, Khunti K. Predicting hospital stay, mortality and readmission in people admitted for hypoglycaemia: Prognostic models derivation and validation. Diabetologia 2017;60:1007–15.

Pickup JC, Reznik Y, Sutton AJ. Glycemic control during continuous subcutaneous insulin infusion versus multiple daily insulin injections in type 2 diabetes: Individual patient data meta-analysis and meta-regression of randomized controlled trials. Diabetes Care 2017;40:715–22.

Law M, Sweeting MJ, Donaldson GC, Wedzicha JA. Misspecification of at-risk periods and distributional assumptions in estimating copd exacerbation rates: The resultant bias in treatment effect estimation. Pharmaceutical Statistics 2017;16:201–9. 

Yates T, Edwardson CL, Henson J, Gray LJ, Ashra NB, Troughton J, Khunti K, Davies MJ. Walking away from type 2 diabetes: A cluster randomized controlled trial. Diabetic Medicine 2017;34:698–707.

Rossi SH, Hsu R, Blick C, Goh V, Nathan P, Nicol D, Fleming S, Sweeting M, Wilson EC, Stewart GD. Meta-analysis of the prevalence of renal cancer detected by abdominal ultrasonography. British Journal of Surgery 2017;104:648–59.

Lambert PC, Wilkes SR, Crowther MJ. Flexible parametric modelling of the cause-specific cumulative incidence function. Statistics in Medicine 2017;36:1429–46.

Latimer NR, Abrams KR, Lambert PC, Crowther MJ, Wailoo AJ, Morden JP, Akehurst RL, Campbell MJ. Adjusting for treatment switching in randomised controlled trials - a simulation study and a simplified two-stage method. Statistical Methods in Medical Research 2017;26:724–51. https://doi.org/10.1177/0962280214557578.

Owen RK, Abrams KR, Mayne C, Slack M, Tincello DG. Comparison of the effectiveness of repeated injections of onabotulinum toxin a for refractory idiopathic detrusor overactivity: Analysis of an open label extension of a randomized trial (the relax study). Neurourology and Urodynamics 2017;36:1201–7. https://doi.org/10.1002/nau.23095.

Mawdsley D, Higgins JP, Sutton AJ, Abrams KR. Accounting for heterogeneity in meta-analysis using a multiplicative model—an empirical study. Research Synthesis Methods 2017;8:43–52. https://doi.org/10.1002/jrsm.1216.

Gray LJ, Troughton J, Khunti K, Davies MJ. Let’s prevent diabetes: From idea to implementation. Practical Diabetes 2017;34:55–7. https://doi.org/10.1002/pdi.2080.

Wu Z, Lin C, Crowther M, Mak H, Yu M, Leung CK-S. Impact of rates of change of lamina cribrosa and optic nerve head surface depths on visual field progression in glaucoma. Investigative Ophthalmology and Visual Science 2017;58:1825–33. https://doi.org/10.1167/iovs.16-20509.

Deave T, Hawkins A, Kumar A, Hayes M, Cooper N, Watson M, Ablewhite J, Coupland C, Sutton A, Majsak-Newman G, McDaid L, Goodenough T, Beckett K, McColl E, Reading R, Kendrick D. Evaluating implementation of a fireprevention injury prevention briefing in children’s centres: Cluster randomised controlled trial. PLoS ONE 2017;12: https://doi.org/10.1371/journal.pone.0172584.

Gholap NN, Achana FA, Davies MJ, Ray KK, Gray L, Khunti K. Long-term mortality after acute myocardial infarction among individuals with and without diabetes: A systematic review and meta-analysis of studies in the post-reperfusion era. Diabetes, Obesity and Metabolism 2017;19:364–74. https://doi.org/10.1111/dom.12827.

Bodicoat DH, Khunti K, Srinivasan BT, Mostafa S, Gray LJ, Davies MJ, Webb DR. Incident type 2 diabetes and the effect of early regression to normoglycaemia in a population with impaired glucose regulation. Diabetic Medicine 2017;34:396–404. https://doi.org/10.1111/dme.13091.

Hua H, Burke DL, Crowther MJ, Ensor J, Tudur Smith C, Riley RD. One-stage individual participant data meta-analysis models: Estimation of treatment-covariate interactions must avoid ecological bias by separating out within-trial and across-trial information. Statistics in Medicine 2017;36:772–89. https://doi.org/10.1002/sim.7171.

Bower H, Björkholm M, Dickman PW, Höglund M, Lambert PC, Andersson TM-L. Reply to d. Pulte et al. Journal of Clinical Oncology 2017;35:696. https://doi.org/10.1200/JCO.2016.70.9279.

Owen RK, Abrams KR, Mayne C, Slack M, Tincello DG. Patient factors associated with onabotulinum toxin a treatment outcome in women with detrusor overactivity. Neurourology and Urodynamics 2017;36:426–31. https://doi.org/10.1002/nau.22948.

Andersson TM-L, Rutherford MJ, Humphreys K. Assessment of lead-time bias in estimates of relative survival for breast cancer. Cancer Epidemiology 2017;46:50–6. https://doi.org/10.1016/j.canep.2016.12.004.

Powell JT, Sweeting MJ, Ulug P, Blankensteijn JD, Lederle FA, Becquemin J-P, Greenhalgh RM, Greenhalgh RM, Beard JD, Buxton MJ, Brown LC, Harris PL, Powell JT, Rose JD, Russell IT, Sculpher MJ, Thompson SG, Lilford RJ, Bell PR, Greenhalgh RM, Whitaker SC, Poole-Wilson PA, Ruckley CV, Campbell WB, Dean MR, Ruttley MS, Coles EC, Powell JT, Halliday A, Gibbs SJ, Brown LC, Epstein D, Sculpher MJ, Thompson SG, Hannon RJ, Johnston L, Bradbury AW, Henderson MJ, Parvin SD, Shepherd DF, Greenhalgh RM, Mitchell AW, Edwards PR, Abbott GT, Higman DJ, Vohra A, Ashley S, Robottom C, Wyatt MG, Rose JD, Byrne D, Edwards R, Leiberman DP, McCarter DH, Taylor PR, Reidy JF, Wilkinson AR, Ettles DF, Clason AE, Leen GL, Wilson NV, Downes M, Walker SR, Lavelle JM, Gough MJ, McPherson S, Scott DJ, Kessell DO, Naylor R, Sayers R, Fishwick NG, Harris PL, Gould DA, Walker MG, Chalmers NC, Garnham A, Collins MA, Beard JD, Gaines PA, Ashour MY, Uberoi R, Braithwaite B, Whitaker SC, Davies JN, Travis S, Hamilton G, Platts A, Shandall A, Sullivan BA, Sobeh M, Matson M, Fox AD, Orme R, Yusef W, Doyle T, Horrocks M, Hardman J, Blair PH, Ellis PK et al. Meta-analysis of individual-patient data from evar-1, dream, over and ace trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years. British Journal of Surgery 2017;104:166–78. https://doi.org/10.1002/bjs.10430.

Wheeler GM, Sweeting MJ, Mander AP, Lee SM, Cheung YK. Modelling semi-attributable toxicity in dual-agent phase i trials with non-concurrent drug administration. Statistics in Medicine 2017;36:225–41. https://doi.org/10.1002/sim.6912.

Mozumder SI, Rutherford MJ, Lambert PC. A flexible parametric competing-risks model using a direct likelihood approach for the cause-specific cumulative incidence function. Stata Journal 2017;17:462–89.

Syriopoulou E, Bower H, Andersson TM-L, Lambert PC, Rutherford MJ. Estimating the impact of a cancer diagnosis on life expectancy by socio-economic group for a range of cancer types in england. British Journal of Cancer 2017;117:1419–26. https://doi.org/10.1038/bjc.2017.300.

Lambert PC. The estimation and modeling of cause-specific cumulative incidence functions using time-dependent weights. Stata Journal 2017;17:181–207.

Barrett JK, Sweeting MJ, Wood AM. Dynamic risk prediction for cardiovascular disease: An illustration using the aric study. Handbook of Statistics 2017;36:47–65. https://doi.org/10.1016/bs.host.2017.05.004.

Sidloff DA, Saratzis A, Sweeting MJ, Michaels J, Powell JT, Thompson SG, Bown MJ. Sex differences in mortality after abdominal aortic aneurysm repair in the uk. British Journal of Surgery 2017;104:1656–64. https://doi.org/10.1002/bjs.10600.

McCarthy M, Edwardson CL, Davies MJ, Henson J, Gray L, Khunti K, Yates T. Change in sedentary time, physical activity, bodyweight, and hba1c in high-risk adults. Medicine and Science in Sports and Exercise 2017;49:1120–5. https://doi.org/10.1249/MSS.0000000000001218.

Leal J, Ahrabian D, Davies MJ, Gray LJ, Khunti K, Yates T, Gray AM. Cost-effectiveness of a pragmatic structured education intervention for the prevention of type 2 diabetes: Economic evaluation of data from the let’s prevent diabetes cluster-randomised controlled trial. BMJ Open 2017;7: https://doi.org/10.1136/bmjopen-2016-013592.

Makady A, Stegenga H, Ciaglia A, Debray TP, Lees M, Happich M, Ryll B, Abrams K, Thwaites R, Garner S, Jonsson P, Goettsch W. Practical implications of using real-world evidence (rwe) in comparative effectiveness research: Learnings from imi-getreal. Future Virology 2017;12:485–90. https://doi.org/10.2217/cer-2017-0044.

O’Donovan G, Chudasama Y, Grocock S, Leigh R, Dalton AM, Gray LJ, Yates T, Edwardson C, Hill S, Henson J, Webb D, Khunti K, Davies MJ, Jones AP, Bodicoat DH, Wells A. The association between air pollution and type 2 diabetes in a large cross-sectional study in leicester: The champions study. Environment International 2017;104:41–7. https://doi.org/10.1016/j.envint.2017.03.027.

Little P, Stuart B, Richard Hobbs FD, Kelly J, Smith ER, Bradbury KJ, Hughes S, Smith PW, Moore MV, Lean ME, Margetts BM, Byrne CD, Griffin S, Davoudianfar M, Hooper J, Yao G, Zhu S, Raftery J, Yardley L. Randomised controlled trial and economic analysis of an internet-based weight management programme: POWeR+ (positive online weight reduction). Health Technology Assessment 2017;21:1–61. https://doi.org/10.3310/hta21040.

Cramb SM, Mengersen KL, Lambert PC, Ryan LM, Baade PD. A flexible parametric approach to examining spatial variation in relative survival. Statistics in Medicine 2016;35:5448–63. https://doi.org/10.1002/sim.7071.

Patel R, Sweeting MJ, Powell JT, Greenhalgh RM. Endovascular versus open repair of abdominal aortic aneurysm in 15-years’ follow-up of the uk endovascular aneurysm repair trial 1 (evar trial 1): A randomised controlled trial. The Lancet 2016;388:2366–74. https://doi.org/10.1016/S0140-6736(16)31135-7.

Band R, Morton K, Stuart B, Raftery J, Bradbury K, Yao GL, Zhu S, Little P, Yardley L, McManus RJ. Home and online management and evaluation of blood pressure (home bp) digital intervention for self-management of uncontrolled, essential hypertension: A protocol for the randomised controlled home bp trial. BMJ Open 2016;6: https://doi.org/10.1136/bmjopen-2016-012684.

Peters SA, Van Der Schouw YT, Wood AM, Sweeting MJ, Moons KG, Weiderpass E, Arriola L, Benetou V, Boeing H, Bonnet F, Butt ST, Clavel-Chapelon F, Drake I, Gavrila D, Key TJ, Klinaki E, Krogh V, Kühn T, Lassale C, Masala G, Matullo G, Merritt M, Molina-Portillo E, Moreno-Iribas C, Nøst TH, Olsen A, Onland-Moret NC, Overvad K, Panico S, Redondo ML, Tjønneland A, Trichopoulou A, Tumino R, Turzanski-Fortner R, Tzoulaki I, Wennberg P, Winkvist A, Thompson SG, Di Angelantonio E, Riboli E, Wareham NJ, Danesh J, Butterworth AS. Parity, breastfeeding and risk of coronary heart disease: A pan-european case-cohort study. European Journal of Preventive Cardiology 2016;23:1755–65. https://doi.org/10.1177/2047487316658571.

Seaton SE, Barker L, Jenkins D, Draper ES, Abrams KR, Manktelow BN. What factors predict length of stay in a neonatal unit: A systematic review. BMJ Open 2016;6: https://doi.org/10.1136/bmjopen-2015-010466.

Ali S, Davies MJ, Brady EM, Gray LJ, Khunti K, Beshyah SA, Hanif W. Guidelines for managing diabetes in ramadan. Diabetic Medicine 2016;33:1315–29. https://doi.org/10.1111/dme.13080.

Willis A, Roshan M, Patel N, Gray LJ, Yates T, Davies M, Khunti K. A community faith centre based screening and educational intervention to reduce the risk of type 2 diabetes: A feasibility study. Diabetes Research and Clinical Practice 2016;120:73–80. https://doi.org/10.1016/j.diabres.2016.07.025.

Cooper NJ, Kendrick D, Timblin C, Hayes M, Majsak-Newman G, Meteyard K, Hawkins A, Kay B. The short-term cost of falls, poisonings and scalds occurring at home in children under 5 years old in england: Multicentre longitudinal study. Injury Prevention 2016;22:334–41. https://doi.org/10.1136/injuryprev-2015-041808.

Little P, Stuart B, Hobbs FR, Kelly J, Smith ER, Bradbury KJ, Hughes S, Smith PW, Moore MV, Lean ME, Margetts BM, Byrne CD, Griffin S, Davoudianfar M, Hooper J, Yao G, Zhu S, Raftery J, Yardley L. An internet-based intervention with brief nurse support to manage obesity in primary care (power+): A pragmatic, parallel-group, randomised controlled trial. The Lancet Diabetes and Endocrinology 2016;4:821–8. https://doi.org/10.1016/S2213-8587(16)30099-7.

Little P, Mullee M, Stuart B, Thomas T, Johnson S, Leydon G, Rabago D, Richards-Hall S, Williamson I, Yao G, Zhu S, Raftery J, Moore M. Effectiveness of steam inhalation and nasal irrigation for chronic or recurrent sinus symptoms in primary care: A pragmatic randomized controlled trial. CMAJ 2016;188:940–9. https://doi.org/10.1503/cmaj.160362.

Brilleman SL, Crowther MJ, May MT, Gompels M, Abrams KR. Joint longitudinal hurdle and time-to-event models: An application related to viral load and duration of the first treatment regimen in patients with hiv initiating therapy. Statistics in Medicine 2016;35:3583–94. https://doi.org/10.1002/sim.6948.

Edgren G, Hjalgrim H, Rostgaard K, Lambert P, Wikman A, Norda R, Titlestad K-E, Erikstrup C, Ullum H, Melbye M, Busch MP, Nyrén O. Transmission of neurodegenerative disorders through blood transfusion: A cohort study. Annals of Internal Medicine 2016;165:316–24. https://doi.org/10.7326/M15-2421.

Troughton J, Chatterjee S, Hill SE, Daly H, Martin Stacey L, Stone MA, Patel N, Khunti K, Yates T, Gray LJ, Davies MJ. Development of a lifestyle intervention using the mrc framework for diabetes prevention in people with impaired glucose regulation. Journal of Public Health (United Kingdom) 2016;38:493–501. https://doi.org/10.1093/pubmed/fdv110.

Phillips RS, Stewart LA, Phillips RS, Bhuller K, Sung L, Sung L, Ammann RA, Tissing WJ, Lehrnbecher T, Haeusler GM, Bauters T, Laureys G, Spassova M, Klaassen R, Alexander S, Silva P, Tordecilla J, Paesmans M, Donnelly JP, Simon A, Hann IM, Ranasinghe N, Riley RD, Chisholm J, Yeomanson D, Sutton AJ, Dommett R, Gupta A, Castagnola E, Haupt R, Meidema K, Kuehne T, Kitanovski L, Niggli F, Nadal D, Tezcan G, Hakim H, Stryjewski G. Risk stratification in febrile neutropenic episodes in adolescent/young adult patients with cancer. European Journal of Cancer 2016;64:101–6. https://doi.org/10.1016/j.ejca.2016.05.027.

Bower H, Björkholm M, Dickman PW, Höglund M, Lambert PC, Andersson TM-L. Life expectancy of patients with chronic myeloid leukemia approaches the life expectancy of the general population. Journal of Clinical Oncology 2016;34:2851–7. https://doi.org/10.1200/JCO.2015.66.2866.

Achana F, Sutton AJ, Kendrick D, Hayes M, Jones DR, Hubbard SJ, Cooper NJ. A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health 2016;16: https://doi.org/10.1186/s12889-016-3334-0.

Aujla N, Walker M, Sprigg N, Abrams K, Massey A, Vedhara K. Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours? A systematic review and meta-analysis. Psychology and Health 2016;31:931–58. https://doi.org/10.1080/08870446.2016.1153640.

Batson S, Sutton A, Abrams K. Exploratory network meta regression analysis of stroke prevention in atrial fibrillation fails to identify any interactions with treatment effect. PLoS ONE 2016;11: https://doi.org/10.1371/journal.pone.0161864.

Ulug P, Powell JT, Sweeting MJ, Bown MJ, Thompson SG. Meta-analysis of the current prevalence of screen-detected abdominal aortic aneurysm in women. The British Journal of Surgery 2016;103:1097–104. https://doi.org/10.1002/bjs.10225.

Major RW, Oozeerally I, Dawson S, Riddleston H, Gray LJ, Brunskill NJ. Aspirin and cardiovascular primary prevention in non-endstage chronic kidney disease: A meta-analysis. Atherosclerosis 2016;251:177–82. https://doi.org/10.1016/j.atherosclerosis.2016.06.013.

Khunti K, Gillies CL, Dallosso H, Brady EM, Gray LJ, Kilgallen G, Willis A, Zafar A, Davies MJ. Assessment of response rates and yields for two opportunistic tools for early detection of non-diabetic hyperglycaemia and diabetes (attend). A randomised controlled trial and cost-effectiveness analysis. Diabetes Research and Clinical Practice 2016;118:12–20. https://doi.org/10.1016/j.diabres.2016.04.054.

Htike ZZ, Yates T, Brady EM, Webb D, Gray LJ, Swarbrick D, McCann GP, Khunti K, Davies MJ. Rationale and design of the randomised controlled trial to assess the impact of liraglutide on cardiac function and structure in young adults with type 2 diabetes (the lydia study). Cardiovascular Diabetology 2016;15: https://doi.org/10.1186/s12933-016-0421-6.

Wheeler GM, Sweeting MJ, Mander AP. AplusB: A web application for investigating a + b designs for phase i cancer clinical trials. PLoS ONE 2016;11: https://doi.org/10.1371/journal.pone.0159026.

Graves N, Wloch C, Wilson J, Barnett A, Sutton A, Cooper N, Merollini K, McCreanor V, Cheng Q, Burn E, Lamagni T, Charlett A. A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review. Health Technology Assessment 2016;20:1–144. https://doi.org/10.3310/hta20540.

Salmasi MY, Acharya M, Humayun N, Baskaran D, Hubbard S, Vohra H. Is valve repair preferable to valve replacement in ischaemic mitral regurgitation? A systematic review and meta-analysis. European Journal of Cardio-Thoracic Surgery 2016;50:17–28. https://doi.org/10.1093/ejcts/ezw053.

Gray LJ, Yates T, Troughton J, Khunti K, Davies MJ. Engagement, retention, and progression to type 2 diabetes: A retrospective analysis of the cluster-randomised "let’s prevent diabetes" trial. PLoS Medicine 2016;13: https://doi.org/10.1371/journal.pmed.1002078.

Nazir SA, McCann GP, Greenwood JP, Kunadian V, Khan JN, Mahmoud IZ, Blackman DJ, Been M, Abrams KR, Shipley L, Wilcox R, Adgey AA, Gershlick AH. Strategies to attenuate micro-vascular obstruction during p-pci: The randomized reperfusion facilitated by local adjunctive therapy in st-elevation myocardial infarction trial. European Heart Journal 2016;37:1910–9. https://doi.org/10.1093/eurheartj/ehw136.

Alabas OA, Hall M, Dondo TB, Rutherford MJ, Timmis AD, Batin PD, Deanfield JE, Hemingway H, Gale CP. Long-term excess mortality associated with diabetes following acute myocardial infarction: A population-based cohort study. Journal of Epidemiology and Community Health 2016;71:25–32. https://doi.org/10.1136/jech-2016-207402.

Asaria M, Walker S, Palmer S, Gale CP, Shah AD, Abrams KR, Crowther M, Manca A, Timmis A, Hemingway H, Sculpher M. Using electronic health records to predict costs and outcomes in stable coronary artery disease. Heart 2016;102:755–62. https://doi.org/10.1136/heartjnl-2015-308850.

Latimer NR, Bell H, Abrams KR, Amonkar MM, Casey M. Adjusting for treatment switching in the metric study shows further improved overall survival with trametinib compared with chemotherapy. Cancer Medicine 2016;5:806–15. https://doi.org/10.1002/cam4.643.

O’Donovan G, Bakrania K, Ghouri N, Yates T, Gray LJ, Hamer M, Stamatakis E, Khunti K, Davies M, Sattar N, Gill JM. Nonexercise equations to estimate fitness in white european and south asian men. Medicine and Science in Sports and Exercise 2016;48:854–9. https://doi.org/10.1249/MSS.0000000000000836.

Crowther MJ, Andersson TM-L, Lambert PC, Abrams KR, Humphreys K. Joint modelling of longitudinal and survival data: Incorporating delayed entry and an assessment of model misspecification. Statistics in Medicine 2016;35:1193–209. https://doi.org/10.1002/sim.6779.

Bujkiewicz S, Thompson JR, Riley RD, Abrams KR. Bayesian meta-analytical methods to incorporate multiple surrogate endpoints in drug development process. Statistics in Medicine 2016;35:1063–89. https://doi.org/10.1002/sim.6776.

Seidu S, Achana FA, Gray LJ, Davies MJ, Khunti K. Effects of glucose-lowering and multifactorial interventions on cardiovascular and mortality outcomes: A meta-analysis of randomized control trials. Diabetic Medicine 2016;33:280–9. https://doi.org/10.1111/dme.12885.

Davies MJ, Gray LJ, Troughton J, Gray A, Tuomilehto J, Farooqi A, Khunti K, Yates T, Bancroft M, Ahrabian D, Cowling P, Greaves C, Sheppard D, Leal J, Abrams K, Bodicoat D, Carter P, Dunkley A, Patel N, Russell C, Horne R, Spong R, Stone M, Taub N, Webb D, Amin S, Barnett J, Berkeley H, Bonar M, Boyles L, Bray P, Cairns N, Campbell S, Carey M, Chatterjee S, Currie C, Daly H, Enright S, Goldby S, Gray G, Henson J, Hiles S, Hill S, Hill J, Holdsworth H, Htike ZZ, Jamal S, Jarvis J, Johnson C, Jones J, Jones K, Khan S, Khulpateea A, Leonard J, Mani H, Martin-Stacey L, Morgan V, Morris F, Mostafa S, Northern A, O’Brien K, Patel H, Plummer R, Porter S, Radia M, Realf K, Richmond D, Saker R, Sennet J, Stribling B, Wilmott E, Wilson C, Wilson P. A community based primary prevention programme for type 2 diabetes integrating identification and lifestyle intervention for prevention: The let’s prevent diabetes cluster randomised controlled trial. Preventive Medicine 2016;84:48–56. https://doi.org/10.1016/j.ypmed.2015.12.012.

Bower H, Andersson TM-L, Bjorkholm M, Dickman PW, Lambert PC, Derolf AR. Continued improvement in survival of acute myeloid leukemia patients: An application of the loss in expectation of life. Blood Cancer Journal 2016;6: https://doi.org/10.1038/bcj.2016.3.

Bower H, Crowther MJ, Lambert PC. Strcs: A command for fitting flexible parametric survival models on the log-hazard scale. Stata Journal 2016;16:989–1012.

Walker S, Asaria M, Manca A, Palmer S, Gale CP, Shah AD, Abrams KR, Crowther M, Timmis A, Hemingway H, Sculpher M. Long-term healthcare use and costs in patients with stable coronary artery disease: A population-based cohort using linked health records (caliber). European Heart Journal - Quality of Care and Clinical Outcomes 2016;2:125–40. https://doi.org/10.1093/ehjqcco/qcw003.

Willis A, Gray L, Khunti K. Ensuring health equality amid the great diabetes epidemic: Translating the leicester self-assessment risk score. Journal of Diabetes Nursing 2016;20:374–5. https://doi.org/10.1155/2016/8107108.

Nunn A, Bath PM, Gray LJ. Analysis of the modified rankin scale in randomised controlled trials of acute ischaemic stroke: A systematic review. Stroke Research and Treatment 2016;2016: https://doi.org/10.1155/2016/9482876.

Patel N, Willis A, Stone M, Barber S, Gray L, Davies M, Khunti K. Developing a conceptually equivalent type 2 diabetes risk score for indian gujaratis in the uk. Journal of Diabetes Research 2016;2016: https://doi.org/10.1155/2016/8107108.

Alabas OA, Brogan RA, Hall M, Almudarra S, Rutherford MJ, Dondo TB, Feltbower R, Curzen N, De Belder M, Ludman P, Gale CP. Determinants of excess mortality following unprotected left main stem percutaneous coronary intervention. Heart 2016;102:1287–95. https://doi.org/10.1136/heartjnl-2015-308739.

Grieve R, Abrams K, Claxton K, Goldacre B, James N, Nicholl J, Parmar M, Parker C, Sekhon JS, Smeeth L, Spiegelhalter D, Sculpher M. Cancer drugs fund requires further reform. BMJ (Online) 2016;354: https://doi.org/10.1136/bmj.i5090.

Murray E, Dack C, Barnard M, Farmer A, Li J, Michie S, Pal K, Parrott S, Ross J, Sweeting M, Wood B, Yardley L. HeLP-diabetes: Randomised controlled trial protocol. BMC Health Services Research 2015;15: https://doi.org/10.1186/s12913-015-1246-9.

O’Connell SE, Jackson BR, Edwardson CL, Yates T, Biddle SJ, Davies MJ, Dunstan D, Esliger D, Gray L, Miller P, Munir F. Providing nhs staff with height-adjustable workstations and behaviour change strategies to reduce workplace sitting time: Protocol for the stand more at (smart) work cluster randomised controlled trial health behavior, health promotion and society. BMC Public Health 2015;15: https://doi.org/10.1186/s12889-015-2532-5.

Jones E, Sweeting MJ, Sharp SJ, Thompson SG. A method making fewer assumptions gave the most reliable estimates of exposure-outcome associations in stratified case-cohort studies. Journal of Clinical Epidemiology 2015;68:1397–405. https://doi.org/10.1016/j.jclinepi.2015.04.007.

Powell JT, Sweeting MJ. Retrospective studies. European Journal of Vascular and Endovascular Surgery 2015;50:675. https://doi.org/10.1016/j.ejvs.2015.07.005.

Woods B, Hawkins N, Mealing S, Sutton A, Abraham WT, Beshai JF, Klein H, Sculpher M, Plummer CJ, Cowie MR. Individual patient data network meta-analysis of mortality effects of implantable cardiac devices. Heart 2015;101:1800–6. https://doi.org/10.1136/heartjnl-2015-307634.

Little P, Stuart B, Hobbs FD, Moore M, Barnett J, Popoola D, Middleton K, Kelly J, Mullee M, Raftery J, Yao G, Carman W, Fleming D, Stokes-Lampard H, Williamson I, Joseph J, Miller S, Yardley L. An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (primit): A primary care randomised trial. The Lancet 2015;386:1631–9. https://doi.org/10.1016/S0140-6736(15)60127-1.

Bodicoat DH, Carter P, Comber A, Edwardson C, Gray LJ, Hill S, Webb D, Yates T, Davies MJ, Khunti K. Is the number of fast-food outlets in the neighbourhood related to screen-detected type 2 diabetes mellitus and associated risk factors? Public Health Nutrition 2015;18:1698–705. https://doi.org/10.1017/S1368980014002316.

Mani H, Davies MJ, Bodicoat DH, Levy MJ, Gray LJ, Howlett TA, Khunti K. Clinical characteristics of polycystic ovary syndrome: Investigating differences in white and south asian women. Clinical Endocrinology 2015;83:542–9. https://doi.org/10.1111/cen.12784.

Williams JE, Peacock J, Gubbay AN, Kuo PY, Ellard R, Gupta R, Riley J, Sauzet O, Raftery J, Yao G, Ross J. Routine screening for pain combined with a pain treatment protocol in head and neck cancer: A randomised controlled trial. British Journal of Anaesthesia 2015;115:621–8. https://doi.org/10.1093/bja/aev263.

Brill SE, Law M, El-Emir E, Allinson JP, James P, Maddox V, Donaldson GC, McHugh TD, Cookson WO, Moffatt MF, Nazareth I, Hurst JR, Calverley PM, Sweeting MJ, Wedzicha JA. Effects of different antibiotic classes on airway bacteria in stable copd using culture and molecular techniques: A randomised controlled trial. Thorax 2015;70:930–8. https://doi.org/10.1136/thoraxjnl-2015-207194.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P. Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: An open randomized controlled trial. CMAJ 2015;187:961–9. https://doi.org/10.1503/cmaj.141608.

Boyle PJ, Smith LK, Cooper NJ, Williams KS, O’Connor H. Gender balance: Women are funded more fairly in social science. Nature 2015;525:181–3. https://doi.org/10.1038/525181a.

Khunti K, Mani H, Achana F, Cooper N, Gray LJ, Davies MJ, Schooling CM. Systematic review and meta-analysis of response rates and diagnostic yield of screening for type 2 diabetes and those at high risk of diabetes. PLoS ONE 2015;10: https://doi.org/10.1371/journal.pone.0135702.

Lambert PC, Dickman PW, Rutherford MJ. Comparison of different approaches to estimating age standardized net survival. BMC Medical Research Methodology 2015;15: https://doi.org/10.1186/s12874-015-0057-3.

Braithwaite B, Greenhalgh RM, Grieve R, Hassan TB, Moore F, Nicholson AA, Soong CV, Heatley F, Anjum A, Kalinowska G, Gomes M, Powell JT, Hinchliffe R, Sweeting M, Thompson MM, Thompson SG, Ulug P, Roberts I, Bell PR, Cheetham A, Stephany J, Halliday AW, Warlow C, Lamont P, Moss J, Tijssen J, Ashleigh R, Thompson M, Thompson L, Cheshire NJ, Boyle JR, Serracino-Inglott F, Hinchliffe RJ, Bell R, Wilson N, Bown M, Dennis M, Davis M, Howell S, Wyatt MG, Valenti D, Bachoo P, Walker P, MacSweeney S, Davies JN, Rittoo D, Parvin SD, Yusuf W, Nice C, Chetter I, Howard A, Chong P, Bhat R, McLain D, Gordon A, Lane I, Hobbs S, Pillay W, Rowlands T, El-Tahir A, Asquith J, Cavanagh S, Dubois L, Forbes TL, Ashworth E, Baker S, Barakat H, Brady C, Brown J, Bufton C, Chance T, Chrisopoulou A, Cockell M, Croucher A, Dabee L, Dewhirst N, Evans J, Gibson A, Gorst S, Gough M, Graves L, Griffin M, Hatfield J, Hogg F, Howard S, Hughes C, Metcalfe D, Lapworth M, Massey I, Novick T, Owen G, Parr N, Pintar D, Spencer S, Thomson C, Thunder O, Wallace T, Ward S, Wealleans V et al. Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: One-year outcomes from the improve randomized trial. European Heart Journal 2015;36:2061–9. https://doi.org/10.1093/eurheartj/ehv125.

Hultcrantz M, Wilkes SR, Kristinsson SY, Andersson TM-L, Derolf AR, Eloranta S, Samuelsson J, Landgren O, Dickman PW, Lambert PC, Björkholm M. Risk and cause of death in patients diagnosed with myeloproliferative neoplasms in sweden between 1973 and 2005: A population-based study. Journal of Clinical Oncology 2015;33:2288–95. https://doi.org/10.1200/JCO.2014.57.6652.

Yates T, Griffin S, Bodicoat DH, Brierly G, Dallosso H, Davies MJ, Eborall H, Edwardson C, Gillett M, Gray L, Hardeman W, Hill S, Morton K, Sutton S, Troughton J, Khunti K. PRomotion of physical activity through structured education with differing levels of ongoing support for people at high risk of type 2 diabetes (propels): Study protocol for a randomized controlled trial. Trials 2015;16: https://doi.org/10.1186/s13063-015-0813-z.

Gray LJ, Dales J, Brady EM, Khunti K, Hanif W, Davies MJ. Safety and effectiveness of non-insulin glucose-lowering agents in the treatment of people with type 2 diabetes who observe ramadan: A systematic review and meta-analysis. Diabetes, Obesity and Metabolism 2015;17:639–48. https://doi.org/10.1111/dom.12462.

Halligan S, Wooldrage K, Dadswell E, Shah U, Kralj-Hans I, Von Wagner C, Faiz O, Teare J, Edwards R, Kay C, Yao G, Lilford RJ, Morton D, Wardle J, Atkin W. Identification of extracolonic pathologies by computed tomographic colonography in colorectal cancer symptomatic patients. Gastroenterology 2015;149:89–101.e5. https://doi.org/10.1053/j.gastro.2015.03.011.

Gould AL, Boye ME, Crowther MJ, Ibrahim JG, Quartey G, Micallef S, Bois FY. Responses to discussants of ’joint modeling of survival and longitudinal non-survival data: Current methods and issues. Report of the dia bayesian joint modeling working group’. Statistics in Medicine 2015;34:2202–3. https://doi.org/10.1002/sim.6502.

Potts JE, Gray LJ, Brady EM, Khunti K, Davies MJ, Bodicoat DH. The effect of glucagon-like peptide 1 receptor agonists on weight loss in type 2 diabetes: A systematic review and mixed treatment comparison meta-analysis. PLoS ONE 2015;10: https://doi.org/10.1371/journal.pone.0126769.

Edridge CL, Dunkley AJ, Bodicoat DH, Rose TC, Gray LJ, Davies MJ, Khunti K. Prevalence and incidence of hypoglycaemia in 532,542 people with type 2 diabetes on oral therapies and insulin: A systematic review and meta-analysis of population based studies. PLoS ONE 2015;10: https://doi.org/10.1371/journal.pone.0126427.

Lewis RA, Williams NH, Sutton AJ, Burton K, Din NU, Matar HE, Hendry M, Phillips CJ, Nafees S, Fitzsimmons D, Rickard I, Wilkinson C. Comparative clinical effectiveness of management strategies for sciatica: Systematic review and network meta-analyses. Spine Journal 2015;15:1461–77. https://doi.org/10.1016/j.spinee.2013.08.049.

Andersson TM-L, Dickman PW, Eloranta S, Sjövall A, Lambe M, Lambert PC. The loss in expectation of life after colon cancer: A population-based study. BMC Cancer 2015;15: https://doi.org/10.1186/s12885-015-1427-2.

Gillett M, Brennan A, Watson P, Khunti K, Davies M, Mostafa S, Gray LJ. The cost-effectiveness of testing strategies for type 2 diabetes: A modelling study. Health Technology Assessment 2015;19:1–80. https://doi.org/10.3310/hta19330.

Nikiphorou E, Davies C, Mugford M, Cooper N, Brooksby A, Bunn DK, Young A, M. Verstappen SM, M. Symmons DP, MacGregor AJ. Direct health costs of inflammatory polyarthritis 10 years after disease onset: Results from the norfolk arthritis register. Journal of Rheumatology 2015;42:794–8. https://doi.org/10.3899/jrheum.140528.

Achana FA, Sutton AJ, Kendrick D, Wynn P, Young B, Jones DR, Hubbard SJ, Cooper NJ. The effectiveness of different interventions to promote poison prevention behaviours in households with children: A network meta-analysis. PLoS ONE 2015;10: https://doi.org/10.1371/journal.pone.0121122.

Rutherford MJ, Abel GA, Greenberg DC, Lambert PC, Lyratzopoulos G. The impact of eliminating age inequalities in stage at diagnosis on breast cancer survival for older women. British Journal of Cancer 2015;112:S124–8. https://doi.org/10.1038/bjc.2015.51.

Rutherford MJ, Ironmonger L, Ormiston-Smith N, Abel GA, Greenberg DC, Lyratzopoulos G, Lambert PC. Estimating the potential survival gains by eliminating socioeconomic and sex inequalities in stage at diagnosis of melanoma. British Journal of Cancer 2015;112:S116–23. https://doi.org/10.1038/bjc.2015.50.

Rutherford MJ. Care needed in interpretation of cancer survival measures. The Lancet 2015;385:1162–3. https://doi.org/10.1016/S0140-6736(14)62292-3.

Latimer NR, Abrams KR, Amonkar MM, Stapelkamp C, Swann RS. Adjusting for the confounding effects of treatment switching—the break-3 trial: Dabrafenib versus dacarbazine. Oncologist 2015;20:798–805. https://doi.org/10.1634/theoncologist.2014-0429.

Kandala N-B, Connock M, Pulikottil-Jacob R, Sutcliffe P, Crowther MJ, Grove A, Mistry H, Clarke A. Setting benchmark revision rates for total hip replacement: Analysis of registry evidence. BMJ (Online) 2015;350: https://doi.org/10.1136/bmj.h756.

Crawford MJ, Sanatinia R, Barrett B, Byford S, Dean M, Green J, Jones R, Leurent B, Sweeting MJ, Touquet R, Greene L, Tyrer P, Ward H, Lingford-Hughes A. The clinical and cost-effectiveness of brief advice for excessive alcohol consumption among people attending sexual health clinics: A randomised controlled trial. Sexually Transmitted Infections 2015;91:37–43. https://doi.org/10.1136/sextrans-2014-051561.

Hubbard S, Cooper N, Kendrick D, Young B, Wynn PM, He Z, Miller P, Achana F, Sutton A. Network meta-analysis to evaluate the effectiveness of interventions to prevent falls in children under age 5 years. Injury Prevention 2015;21:98–108. https://doi.org/10.1136/injuryprev-2013-041135.

Rutherford MJ, Crowther MJ, Lambert PC. The use of restricted cubic splines to approximate complex hazard functions in the analysis of time-to-event data: A simulation study. Journal of Statistical Computation and Simulation 2015;85:777–93. https://doi.org/10.1080/00949655.2013.845890.

Crowther MJ, Lambert PC. Reply to letter to the editor by remontet et al. Statistics in Medicine 2015;34:3378–80. https://doi.org/10.1002/sim.6606.

Rutherford MJ, Andersson TM-L, Møller H, Lambert PC. Understanding the impact of socioeconomic differences in breast cancer survival in england and wales: Avoidable deaths and potential gain in expectation of life. Cancer Epidemiology 2015;39:118–25. https://doi.org/10.1016/j.canep.2014.11.002.

Owen RK, Tincello DG, Keith RA. Network meta-analysis: Development of a three-level hierarchical modeling approach incorporating dose-related constraints. Value in Health 2015;18:116–26. https://doi.org/10.1016/j.jval.2014.10.006.

Mander AP, Sweeting MJ. A product of independent beta probabilities dose escalation design for dual-agent phase i trials. Statistics in Medicine 2015;34:1261–76. https://doi.org/10.1002/sim.6434.

Major RW, Cheung CK, Gray LJ, Brunskill NJ. Statins and cardiovascular primary prevention in ckd: A meta-analysis. Clinical Journal of the American Society of Nephrology 2015;10:732–9. https://doi.org/10.2215/CJN.07460714.

Sweeting MJ, Ulug P, Powell JT, Desgranges P, Balm R. Ruptured aneurysm trials: The importance of longer-term outcomes and meta-analysis for 1-year mortality. European Journal of Vascular and Endovascular Surgery 2015;50:297–302. https://doi.org/10.1016/j.ejvs.2015.04.015.

Sweeting MJ, Balm R, Desgranges P, Ulug P, Powell JT. Individual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm. British Journal of Surgery 2015;102:1229–39. https://doi.org/10.1002/bjs.9852.

Stotter A, Reed MW, Gray LJ, Moore N, Robinson TG. Comprehensive geriatric assessment and predicted 3-year survival in treatment planning for frail patients with early breast cancer. British Journal of Surgery 2015;102:525–33. https://doi.org/10.1002/bjs.9755.

Lawrence Gould A, Boye ME, Crowther MJ, Ibrahim JG, Quartey G, Micallef S, Bois FY. Joint modeling of survival and longitudinal non-survival data: Current methods and issues. Report of the dia bayesian joint modeling working group. Statistics in Medicine 2015;34:2181–95. https://doi.org/10.1002/sim.6141.

Major RW, Davies MJ, Crasto W, Gray LJ, Webb DR, Khunti K. Association between undiagnosed hypertension and microalbuminuria in south asians without known diabetes. Journal of Human Hypertension 2015;29:185–9. https://doi.org/10.1038/jhh.2014.62.

Jelleyman C, Yates T, O’Donovan G, Gray LJ, King JA, Khunti K, Davies MJ. The effects of high-intensity interval training on glucose regulation and insulin resistance: A meta-analysis. Obesity Reviews 2015;16:942–61. https://doi.org/10.1111/obr.12317.

Halligan S, Dadswell E, Wooldrage K, Wardle J, Wagner C von, Lilford R, Yao GL, Zhu S, Atkin W. Computed tomographic colonography compared with colonoscopy or barium enema for diagnosis of colorectal cancer in older symptomatic patients: Two multicentre randomised trials with economic evaluation (the siggar trials). Health Technology Assessment 2015;19: https://doi.org/10.3310/hta19540.

Powell JT, Sweeting MJ, Thompson MM, Hinchliffe RJ, Ashleigh R, Bell R, Greenhalgh RM, Thompson SG, Ulug P. The effect of aorticmorphology on peri-operative mortality of ruptured abdominal aortic aneurysm. European Heart Journal 2015;36:1328–34. https://doi.org/10.1093/eurheartj/ehu521.

Nolan T, Dack C, Pal K, Ross J, Stevenson FA, Peacock R, Pearson M, Spiegelhalter D, Sweeting M, Murray E. Patient reactions to a web-based cardiovascular risk calculator in type 2 diabetes: A qualitative study in primary care. British Journal of General Practice 2015;65:e152–60. https://doi.org/10.3399/bjgp15X683953.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Breen M, Bradley B, Kelly S, Yao G, Raftery J, Mant D, Little P. An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care. Health Technology Assessment 2015;19:1–149. https://doi.org/10.3310/hta19720.

Clarke A, Pulikottil-Jacob R, Grove A, Freeman K, Mistry H, Tsertsvadze A, Connock M, Court R, Kandala N-B, Costa M, Suri G, Metcalfe D, Crowther M, Morrow S, Johnson S, Sutcliffe P. Total hip replacement and surface replacement for the treatment of pain and disability resulting from end-stage arthritis of the hip (review of technology appraisal guidance 2 and 44): Systematic review and economic evaluation. Health Technology Assessment (Winchester, England) 2015;19:1–"668, vii–viii". https://doi.org/10.3310/hta19100.

Freitag D, Butterworth AS, Willeit P, Howson JM, Burgess S, Kaptoge S, Young R, Ho WK, Wood AM, Sweeting M, Spackman S, Staley JR, Ramond A, Harshfield E, Nielsen SF, Grande P, Lange LA, Bown MJ, Jones GT, Scott RA, Bevan S, Porcu E, Thorleifsson G, Zeng L, Kessler T, Nikpay M, Do R, Zhang W, Hopewell JC, Kleber M, Delgado GE, Nelson CP, Goel A, Bis JC, Dehghan A, Ligthart S, Smith AV, Qu L, Hof FN van ’t, Bakker PI de, Baas AF, Rij A van, Tromp G, Kuivaniemi H, Ritchie MD, Verma SS, Crawford DC, Malinowski J, Andrade M de, Kullo IJ, Peissig PL, McCarty CA, Böttinger EP, Gottesman O, Crosslin DR, Carrell DS, Rasmussen-Torvik LJ, Pacheco JA, Huang J, Timpson NJ, Kettunen J, Ala-Korpela M, Mitchell GF, Parsa A, Wilkinson IB, Gorski M, Li Y, Franceschini N, Keller MF, Ganesh SK, Langefeld CD, Bruijn L, Brown MA, Evans DM, Baltic S, Ferreira MA, Baurecht H, Weidinger S, Franke A, Lubitz SA, Müller-Nurasyid M, Felix JF, Smith NL, Sudman M, Thompson SD, Zeggini E, Panoutsopoulou K, Nalls MA, Singleton A, Polychronakos C, Bradfield JP, Hakonarson H, Easton DF, Thompson D, Tomlinson IP, Dunlop M, Hemminki K, Morgan G, Eisen T et al. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A mendelian randomisation analysis. The Lancet Diabetes and Endocrinology 2015;3:243–53. https://doi.org/10.1016/S2213-8587(15)00034-0.

Crowther MJ, Lambert PC. A general framework for parametric survival analysis. Statistics in Medicine 2014;33:5280–97. https://doi.org/10.1002/sim.6300.

Wynn P, Stewart J, Kumar A, Clacy R, Coffey F, Cooper N, Coupland C, Deave T, Hayes M, McColl E, Reading R, Sutton A, Watson M, Kendrick D. Keeping children safe at home: Protocol for a case-control study of modifiable risk factors for scalds. Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention 2014;20:e11. https://doi.org/10.1136/injuryprev-2014-041255.

Majsak-Newman G, Benford P, Ablewhite J, Clacy R, Coffey F, Cooper N, Coupland C, Hayes M, Kay B, McColl E, Reading R, Sutton A, Stewart J, Watson MC, Kendrick D. Keeping children safe at home: Protocol for a matched case-control study of modifiable risk factors for poisoning. Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention 2014;20:e10. https://doi.org/10.1136/injuryprev-2014-041234.

Letouze D, Yao G, Clarke SC. The costs associated with the public health management of a cluster of meningococcal infection in england. Vaccine 2014;32:5549–51. https://doi.org/10.1016/j.vaccine.2014.08.044.

Crowther MJ, Look MP, Riley RD. Multilevel mixed effects parametric survival models using adaptive gauss-hermite quadrature with application to recurrent events and individual participant data meta-analysis. Statistics in Medicine 2014;33:3844–58. https://doi.org/10.1002/sim.6191.

Nazir SA, Khan JN, Mahmoud IZ, Greenwood JP, Blackman DJ, Kunadian V, Been M, Abrams KR, Wilcox R, Adgey AA, McCann GP, Gershlick AH. The reflo-stemi trial comparing intracoronary adenosine, sodium nitroprusside and standard therapy for the attenuation of infarct size and microvascular obstruction during primary percutaneous coronary intervention: Study protocol for a randomised controlled trial. Trials 2014;15: https://doi.org/10.1186/1745-6215-15-371.

Achana FA, Cooper NJ, Bujkiewicz S, Hubbard SJ, Kendrick D, Jones DR, Sutton AJ. Network meta-analysis of multiple outcome measures accounting for borrowing of information across outcomes. BMC Medical Research Methodology 2014;14: https://doi.org/10.1186/1471-2288-14-92.

Peat G, Riley RD, Croft P, Morley KI, Kyzas PA, Moons KG, Perel P, Steyerberg EW, Schroter S, Altman DG, Hemingway H, Abrams K, Altman D, Briggs A, Brünner N, Croft P, Hayden J, Hingorani A, Hemingway H, Kyzas P, Malats N, Moons K, Perel P, Riley R, Roberts I, Sauerbrei W, Steyerberg E, Timmis A, Windt D van der. Improving the transparency of prognosis research: The role of reporting, data sharing, registration, and protocols. PLoS Medicine 2014;11: https://doi.org/10.1371/journal.pmed.1001671.

Corrigan N, Bankart MJ, Gray LJ, Smith KL. Changing cluster composition in cluster randomised controlled trials: Design and analysis considerations. Trials 2014;15: https://doi.org/10.1186/1745-6215-15-184.

Saramago P, Cooper NJ, Sutton AJ, Hayes M, Dunn K, Manca A, Kendrick D. Cost-effectiveness of interventions for increasing the possession of functioning smoke alarms in households with pre-school children: A modelling study. BMC Public Health 2014;14: https://doi.org/10.1186/1471-2458-14-459.

Lortet-Tieulent J, Soerjomataram I, Ferlay J, Rutherford M, Weiderpass E, Bray F. International trends in lung cancer incidence by histological subtype: Adenocarcinoma stabilizing in men but still increasing in women. Lung Cancer 2014;84:13–22. https://doi.org/10.1016/j.lungcan.2014.01.009.

Willis A, Rivers P, Gray LJ, Davies M, Khunti K. The effectiveness of screening for diabetes and cardiovascular disease risk factors in a community pharmacy setting. PLoS ONE 2014;9: https://doi.org/10.1371/journal.pone.0091157.

Bodicoat DH, Gray LJ, Henson J, Webb D, Guru A, Misra A, Gupta R, Vikram N, Sattar N, Davies MJ, Khunti K. Body mass index and waist circumference cut-points in multi-ethnic populations from the uk and india: The addition-leicester, jaipur heart watch and new delhi cross-sectional studies. PLoS ONE 2014;9: https://doi.org/10.1371/journal.pone.0090813.

Turner EL, Sweeting MJ, Lindfield RJ, Deangelis D. Incidence estimation using a single cross-sectional age-specific prevalence survey with differential mortality. Statistics in Medicine 2014;33:422–35. https://doi.org/10.1002/sim.5942.

Feldman AL, Johansson AL, Lambert PC, Sieurin J, Yang F, Pedersen NL, Wirdefeldt K. Familial coaggregation of alzheimer’s disease and parkinson’s disease: Systematic review and meta-analysis. Neuroepidemiology 2014;42:69–80. https://doi.org/10.1159/000355452.

Andersson TM-L, Eriksson H, Hansson J, Månsson-Brahme E, Dickman PW, Eloranta S, Lambe M, Lambert PC. Estimating the cure proportion of malignant melanoma, an alternative approach to assess long term survival: A population-based study. Cancer Epidemiology 2014;38:93–9. https://doi.org/10.1016/j.canep.2013.12.006.

Deave T, Towner E, McColl E, Reading R, Sutton A, Coupland C, Cooper N, Stewart J, Hayes M, Pitchforth E, Watson M, Kendrick D. Multicentre cluster randomised controlled trial evaluating implementation of a fire prevention injury prevention briefing in children’s centres: Study protocol. BMC Public Health 2014;14: https://doi.org/10.1186/1471-2458-14-69.

Powell JT, Sweeting MJ, Thompson MM, Ashleigh R, Bell R, Gomes M, Greenhalgh RM, Grieve R, Heatley F, Hinchliffe RJ, Thompson SG, Ulug P, Braithwaite B, Cheshire NJ, Grieve RJ, Hassan TB, Howell S, Moore F, Nicholson AA, Soong CV, Anjum A, Roberts I, Bell PR, Cheetham A, Stephany J, Halliday A, Warlow C, Lamont P, Moss J, Tijssen J, Thompson L, Boyle JR, Serracino-Inglott F, Smyth JV, Wilson N, Bown M, Dennis M, Davis M, Wyatt MG, Valenti D, Bachoo P, Walker P, MacSweeney S, Davies JN, Rittoo D, Parvin SD, Yusuf W, Nice C, Chetter I, Howard A, Chong P, Bhat R, McLain D, Gordon A, Lane I, Hobbs S, Pillay W, Rowlands T, El-Tahir A, Asquith J, Cavanagh S, Forbes TL, Awopetu A, Baker S, Bourke P, Brady C, Brown J, Bryce J, Bufton C, Chance T, Chrisopoulou A, Cockell M, Croucher A, Curran G, Dabee L, Dewhirst N, Evans J, Gibson A, Gorst S, Gough M, Graves L, Griffin M, Hatfield J, Hogg F, Howard S, Hughes T, James A, Metcalfe D, Lapworth M, Massey I, Mohalhal A, Novick T, Owen G, Parr N, Pintar D, Smith T, Spencer S, Thomson C, Thunder O et al. Endovascular or open repair strategy for ruptured abdominal aortic aneurysm: 30 day outcomes from improve randomised trial. BMJ (Online) 2014;348: https://doi.org/10.1136/bmj.f7661.

Bujkiewicz S, Thompson JR, Sutton AJ, Cooper NJ, Harrison MJ, Symmons DP, Abrams KR. Use of bayesian multivariate meta-analysis to estimate the haq for mapping onto the eq-5D questionnaire in rheumatoid arthritis. Value in Health 2014;17:109–15. https://doi.org/10.1016/j.jval.2013.11.005.

Achana F, Hubbard S, Sutton A, Kendrick D, Cooper N. An exploration of synthesis methods in public health evaluations of interventions concludes that the use of modern statistical methods would be beneficial. Journal of Clinical Epidemiology 2014;67:376–90. https://doi.org/10.1016/j.jclinepi.2013.09.018.

Tan SH, Cooper NJ, Bujkiewicz S, Welton NJ, Caldwell DM, Sutton AJ. Novel presentational approaches were developed for reporting network meta-analysis. Journal of Clinical Epidemiology 2014;67:672–80. https://doi.org/10.1016/j.jclinepi.2013.11.006.

Rutherford MJ, Thompson JR, Lambert PC. Projecting cancer incidence using age-period-cohort models incorporating restricted cubic splines. International Journal of Biostatistics 2014;8: https://doi.org/10.1515/1557-4679.1411.

Warren FC, Abrams KR, Sutton AJ. Hierarchical network meta-analysis models to address sparsity of events and differing treatment classifications with regard to adverse outcomes. Statistics in Medicine 2014;33:2449–66. https://doi.org/10.1002/sim.6131.

Latimer NR, Abrams KR, Lambert PC, Crowther MJ, Wailoo AJ, Morden JP, Akehurst RL, Campbell MJ. Adjusting survival time estimates to account for treatment switching in randomized controlled trials - an economic evaluation context: Methods, limitations, and recommendations. Medical Decision Making 2014;34:387–402. https://doi.org/10.1177/0272989X13520192.

Dequen P, Sutton AJ, Scott DA, Abrams KR. Searching for indirect evidence and extending the network of studies for network meta-analysis: Case study in venous thromboembolic events prevention following elective total knee replacement surgery. Value in Health 2014;17:416–23. https://doi.org/10.1016/j.jval.2014.02.013.

Zheng H, Barnett AG, Merollini K, Sutton A, Cooper N, Berendt T, Wilson J, Graves N. Control strategies to prevent total hip replacement-related infections: A systematic review and mixed treatment comparison. BMJ Open 2014;4: https://doi.org/10.1136/bmjopen-2013-003978.

Gray LJ, Davies MJ, Khunti K. Screening for type 2 diabetes. 2014.

Schonfeld SJ, McCormack V, Rutherford MJ, Schüz J. Regional variations in german mesothelioma mortality rates: 2000-2010. Cancer Causes and Control 2014;25:615–24. https://doi.org/10.1007/s10552-014-0368-4.

Mavridis D, Welton NJ, Sutton A, Salanti G. A selection model for accounting for publication bias in a full network meta-analysis. Statistics in Medicine 2014;33:5399–412. https://doi.org/10.1002/sim.6321.

Barber SR, Davies MJ, Khunti K, Gray LJ. Risk assessment tools for detecting those with pre-diabetes: A systematic review. Diabetes Research and Clinical Practice 2014;105:1–13. https://doi.org/10.1016/j.diabres.2014.03.007.

Glover MJ, Kim LG, Sweeting MJ, Thompson SG, Buxton MJ. Cost-effectiveness of the national health service abdominal aortic aneurysm screening programme in england. British Journal of Surgery 2014;101:976–82. https://doi.org/10.1002/bjs.9528.

Eloranta S, Lambert PC, Andersson TM-L, Björkholm M, Dickman PW. The application of cure models in the presence of competing risks: A tool for improved risk communication in population-based cancer patient survival. Epidemiology 2014;25:742–8. https://doi.org/10.1097/EDE.0000000000000130.

Gray LJ, Khunti K, Wilmot EG, Yates T, Davies MJ. External validation of two diabetes risk scores in a young uk south asian population. Diabetes Research and Clinical Practice 2014;104:451–8. https://doi.org/10.1016/j.diabres.2014.03.018.

Cure S, Abrams K, Belger M, Dell’Agnello G, Happich M. Systematic literature review and meta-analysis of diagnostic test accuracy in alzheimer’s disease and other dementia using autopsy as standard of truth. Journal of Alzheimer’s Disease 2014;42:169–82. https://doi.org/10.3233/JAD-131559.

Hunter JP, Saratzis A, Sutton AJ, Boucher RH, Sayers RD, Bown MJ. In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias. Journal of Clinical Epidemiology 2014;67:897–903. https://doi.org/10.1016/j.jclinepi.2014.03.003.

Gao H, Hägg S, Sjögren P, Lambert PC, Ingelsson E, Dam RM van. Serum selenium in relation to measures of glucose metabolism and incidence of type 2 diabetes in an older swedish population. Diabetic Medicine 2014;31:787–93. https://doi.org/10.1111/dme.12429.

Carter P, Achana F, Troughton J, Gray LJ, Khunti K, Davies MJ. A mediterranean diet improves hba1c but not fasting blood glucose compared to alternative dietary strategies: A network meta-analysis. Journal of Human Nutrition and Dietetics 2014;27:280–97. https://doi.org/10.1111/jhn.12138.

Chilton M, Dunkley A, Carter P, Davies MJ, Khunti K, Gray LJ. The effect of antiobesity drugs on waist circumference: A mixed treatment comparison. Diabetes, Obesity and Metabolism 2014;16:237–47. https://doi.org/10.1111/dom.12198.

Bodicoat DH, Mundet X, Gray LJ, Cos X, Davies MJ, Khunti K, Cano J-F. Identifying effective pathways in a successful continuous quality improvement programme: The gedaps study. Journal of Evaluation in Clinical Practice 2014;20:1137–43. https://doi.org/10.1111/jep.12253.

Brady EM, Davies MJ, Gray LJ, Saeed MA, Smith D, Hanif W, Khunti K. A randomized controlled trial comparing the glp-1 receptor agonist liraglutide to a sulphonylurea as add on to metformin in patients with established type 2 diabetes during ramadan: The treat 4 ramadan trial. Diabetes, Obesity and Metabolism 2014;16:527–36. https://doi.org/10.1111/dom.12249.

Ghanouni A, Halligan S, Taylor SA, Boone D, Plumb A, Stoffel S, Morris S, Yao GL, Zhu S, Lilford R, Wardle J, Von Wagner C. Quantifying public preferences for different bowel preparation options prior to screening ct colonography: A discrete choice experiment. BMJ Open 2014;4: https://doi.org/10.1136/bmjopen-2013-004327.

Powell JT, Hinchliffe RJ, Thompson MM, Sweeting MJ, Ashleigh R, Bell R, Gomes M, Greenhalgh RM, Grieve RJ, Heatley F, Thompson SG, Ulug P. An endovascular strategy for suspected ruptured abdominal aortic aneurysm brings earlier home discharge but not early survival or cost benefits. European Journal of Vascular and Endovascular Surgery 2014;47:333–4. https://doi.org/10.1016/j.ejvs.2013.12.017.

Carey ME, Mandalia PK, Daly H, Gray LJ, Hale R, Martin Stacey L, Taub N, Skinner TC, Stone M, Heller S, Khunti K, Davies MJ. Increasing capacity to deliver diabetes self-management education: Results of the desmond lay educator non-randomized controlled equivalence trial. Diabetic Medicine 2014;31:1431–8. https://doi.org/10.1111/dme.12483.

Plumb AA, Boone D, Fitzke H, Helbren E, Mallett S, Zhu S, Yao GL, Bell N, Ghanouni A, Von Wagner C, Taylor SA, Altman DG, Lilford R, Halligan S. Detection of extracolonic pathologic findings with ct colonography: A discrete choice experiment of perceived benefits versus harms. Radiology 2014;273:144–52. https://doi.org/10.1148/radiol.14131678.

Morgan JM, Dimitrov BD, Gill J, Kitt S, Andre Ng G, McComb JM, Raftery J, Roderick P, Seed A, Williams SG, Witte KK, Jay Wright D, Yao GL, Cowie MR. Rationale and study design of the rem-hf study: Remote management of heart failure using implanted devices and formalized follow-up procedures. European Journal of Heart Failure 2014;16:1039–45. https://doi.org/10.1002/ejhf.149.

Crawford MJ, Sanatinia R, Barrett B, Byford S, Dean M, Green J, Jones R, Leurent B, Lingford-Hughes A, Sweeting M, Touquet R, Tyrer P, Ward H. The clinical effectiveness and cost-effectiveness of brief intervention for excessive alcohol consumption among people attending sexual health clinics: A randomised controlled trial (shear). Health Technology Assessment 2014;18: https://doi.org/10.3310/hta18300.

Fitzsimmons D, Phillips CJ, Bennett H, Jones M, Williams N, Lewis R, Sutton A, Matar HE, Din N, Burton K, Nafees S, Hendry M, Rickard I, Wilkinson C. Cost-effectiveness of different strategies to manage patients with sciatica. Pain 2014;155:1318–27. https://doi.org/10.1016/j.pain.2014.04.008.

Nicholson KG, Abrams KR, Batham S, Medina MJ, Warren FC, Barer M, Bermingham A, Clark TW, Latimer N, Fraser M, Perera N, Rajakumar K, Zambon M. Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year-olds. Health Technology Assessment 2014;18:1–274. https://doi.org/10.3310/hta18360.

Wilmot EG, Leggate M, Khan JN, Yates T, Gorely T, Bodicoat DH, Khunti K, Kuijer JP, Gray LJ, Singh A, Clarysse P, Croisille P, Nimmo MA, Mccann GP, Davies MJ. Type 2 diabetes mellitus and obesity in young adults: The extreme phenotype with early cardiovascular dysfunction. Diabetic Medicine 2014;31:794–8. https://doi.org/10.1111/dme.12431.

Hinchliffe SR, Scott DA, Lambert PC. Flexible parametric illness-death models. Stata Journal 2013;13:759–75.

Andersson TM-L, Dickman PW, Eloranta S, Lambe M, Lambert PC. Estimating the loss in expectation of life due to cancer using flexible parametric survival models. Statistics in Medicine 2013;32:5286–300. https://doi.org/10.1002/sim.5943.

Tan SH, Bujkiewicz S, Sutton A, Dequen P, Cooper N. Presentational approaches used in the uk for reporting evidence synthesis using indirect and mixed treatment comparisons. Journal of Health Services Research and Policy 2013;18:224–32. https://doi.org/10.1177/1355819613498379.

Choudhury S, Hussain S, Yao G, Hill J, Malik W, Taheri S. The impact of a diabetes local enhanced service on quality outcome framework diabetes outcomes. PLoS ONE 2013;8: https://doi.org/10.1371/journal.pone.0083738.

Takwoing Y, Hopewell S, Tovey D, Sutton AJ. A multicomponent decision tool for prioritising the updating of systematic reviews. BMJ (Online) 2013;347: https://doi.org/10.1136/bmj.f7191.

Boone D, Mallett S, Zhu S, Yao GL, Bell N, Ghanouni A, Von Wagner C, Taylor SA, Altman DG, Lilford R, Halligan S. Patients’ & healthcare professionals’ values regarding true- & false-positive diagnosis when colorectal cancer screening by ct colonography: Discrete choice experiment. PLoS ONE 2013;8: https://doi.org/10.1371/journal.pone.0080767.

Crowther MJ, Lambert PC, Abrams KR. Adjusting for measurement error in baseline prognostic biomarkers included in a time-to-event analysis: A joint modelling approach. BMC Medical Research Methodology 2013;13: https://doi.org/10.1186/1471-2288-13-146.

Yu XQ, De Angelis R, Andersson TM, Lambert PC, O’Connell DL, Dickman PW. Estimating the proportion cured of cancer: Some practical advice for users. Cancer Epidemiology 2013;37:836–42. https://doi.org/10.1016/j.canep.2013.08.014.

Rutherford MJ, Hinchliffe SR, Abel GA, Lyratzopoulos G, Lambert PC, Greenberg DC. How much of the deprivation gap in cancer survival can be explained by variation in stage at diagnosis: An example from breast cancer in the east of england. International Journal of Cancer 2013;133:2192–200. https://doi.org/10.1002/ijc.28221.

Henson J, Yates T, Edwardson CL, Khunti K, Talbot D, Gray LJ, Leigh TM, Carter P, Davies MJ. Sedentary time and markers of chronic low-grade inflammation in a high risk population. PLoS ONE 2013;8: https://doi.org/10.1371/journal.pone.0078350.

Dumville JC, Hinchliffe RJ, Cullum N, Game F, Stubbs N, Sweeting M, Peinemann F. Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus. Cochrane Database of Systematic Reviews 2013;2013: https://doi.org/10.1002/14651858.CD010318.pub2.

Crowther MJ, Lambert PC. Simulating biologically plausible complex survival data. Statistics in Medicine 2013;32:4118–34. https://doi.org/10.1002/sim.5823.

Ahyow LC, Lambert PC, Jenkins DR, Neal KR, Tobin M. Bed occupancy rates and hospital-acquired clostridium difficile infection: A cohort study. Infection Control and Hospital Epidemiology 2013;34:1062–9. https://doi.org/10.1086/673156.

Bujkiewicz S, Thompson JR, Sutton AJ, Cooper NJ, Harrison MJ, Symmons DP, Abrams KR. Multivariate meta-analysis of mixed outcomes: A bayesian approach. Statistics in Medicine 2013;32:3926–43. https://doi.org/10.1002/sim.5831.

Crowther MJ, Hinchliffe SR, Donald A, Sutton AJ. Simulation-based sample-size calculation for designing new clinical trials and diagnostic test accuracy studies to update an existing meta-analysis. Stata Journal 2013;13:451–73.

Gray LJ, Khunti K. Type 2 diabetes risk prediction-do biomarkers increase detection? Diabetes Research and Clinical Practice 2013;101:245–7. https://doi.org/10.1016/j.diabres.2013.07.008.

Thompson SG, Brown LC, Sweeting MJ, Bown MJ, Kim LG, Glover MJ, Buxton MJ, Powell JT. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: Implications for surveillance intervals and their cost-effectiveness. Health Technology Assessment 2013;17:v–118. https://doi.org/10.3310/hta17410.

Corbett MS, Rice SJ, Madurasinghe V, Slack R, Fayter DA, Harden M, Sutton AJ, MacPherson H, Woolacott NF. Acupuncture and other physical treatments for the relief of pain due to osteoarthritis of the knee: Network meta-analysis. Osteoarthritis and Cartilage 2013;21:1290–8. https://doi.org/10.1016/j.joca.2013.05.007.

Lunn D, Barrett J, Sweeting M, Thompson S. Fully bayesian hierarchical modelling in two stages, with application to meta-analysis. Journal of the Royal Statistical Society Series C: Applied Statistics 2013;62:551–72. https://doi.org/10.1111/rssc.12007.

Shah A, Andersson TM-L, Rachet B, Björkholm M, Lambert PC. Survival and cure of acute myeloid leukaemia in england, 1971-2006: A population-based study. British Journal of Haematology 2013;162:509–16. https://doi.org/10.1111/bjh.12425.

Kearns B, Ara R, Wailoo A, Manca A, Alava MH, Abrams K, Campbell M. Good practice guidelines for the use of statistical regression models in economic evaluations. PharmacoEconomics 2013;31:643–52. https://doi.org/10.1007/s40273-013-0069-y.

Wu J, Zhu S, Yao GL, Mohammed MA, Marshall T. Patient factors influencing the prescribing of lipid lowering drugs for primary prevention of cardiovascular disease in uk general practice: A national retrospective cohort study. PLoS ONE 2013;8: https://doi.org/10.1371/journal.pone.0067611.

Hinchliffe SR, Lambert PC. Extending the flexible parametric survival model for competing risks. Stata Journal 2013;13:344–55.

Dickman PW, Lambert PC, Coviello E, Rutherford MJ. Estimating net survival in population-based cancer studies. International Journal of Cancer 2013;133:519–21. https://doi.org/10.1002/ijc.28041.

Cooper NJ, Spiegelhalter D, Bujkiewicz S, Dequen P, Sutton AJ. Use of implicit and explicit bayesian methods in health technology assessment. International Journal of Technology Assessment in Health Care 2013;29:336–42. https://doi.org/10.1017/S0266462313000354.

Dias S, Welton NJ, Sutton AJ, Ades AE. Evidence synthesis for decision making 5: The baseline natural history model. Medical Decision Making 2013;33:657–70. https://doi.org/10.1177/0272989X13485155.

Dias S, Sutton AJ, Welton NJ, Ades AE. Evidence synthesis for decision making 3: Heterogeneity - subgroups, meta-regression, bias, and bias-adjustment. Medical Decision Making 2013;33:618–40. https://doi.org/10.1177/0272989X13485157.

Dias S, Welton NJ, Sutton AJ, Ades AE. Evidence synthesis for decision making 1: Introduction. Medical Decision Making 2013;33:597–606. https://doi.org/10.1177/0272989X13487604.

Dias S, Sutton AJ, Welton NJ, Ades AE. Evidence synthesis for decision making 6: Embedding evidence synthesis in probabilistic cost-effectiveness analysis. Medical Decision Making 2013;33:671–8. https://doi.org/10.1177/0272989X13487257.

Dias S, Sutton AJ, Ades AE, Welton NJ. Evidence synthesis for decision making 2: A generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials. Medical Decision Making 2013;33:607–17. https://doi.org/10.1177/0272989X12458724.

Ades AE, Caldwell DM, Reken S, Welton NJ, Sutton AJ, Dias S. Evidence synthesis for decision making 7: A reviewer’s checklist. Medical Decision Making 2013;33:679–91. https://doi.org/10.1177/0272989X13485156.

Dias S, Welton NJ, Sutton AJ, Caldwell DM, Lu G, Ades AE. Evidence synthesis for decision making 4: Inconsistency in networks of evidence based on randomized controlled trials. Medical Decision Making 2013;33:641–56. https://doi.org/10.1177/0272989X12455847.

Hinchliffe SR, Seaton SE, Lambert PC, Draper ES, Field DJ, Manktelow BN. Modelling time to death or discharge in neonatal care: An application of competing risks. Paediatric and Perinatal Epidemiology 2013;27:426–33. https://doi.org/10.1111/ppe.12053.

Morris DH, Khunti K, Achana F, Srinivasan B, Gray LJ, Davies MJ, Webb D. Progression rates from hba<inf>1c</inf> 6.0-6.4. Diabetologia 2013;56:1489–93. https://doi.org/10.1007/s00125-013-2902-4.

Ghanouni A, Smith SG, Halligan S, Plumb A, Boone D, Yao GL, Zhu S, Lilford R, Wardle J, Von Wagner C. Public preferences for colorectal cancer screening tests: A review of conjoint analysis studies. Expert Review of Medical Devices 2013;10:489–99. https://doi.org/10.1586/17434440.2013.811867.

Novielli N, Cooper NJ, Sutton AJ. Evaluating the cost-effectiveness of diagnostic tests in combination: Is it important to allow for performance dependency? Value in Health 2013;16:536–41. https://doi.org/10.1016/j.jval.2013.02.015.

Novielli N, Sutton AJ, Cooper NJ. Meta-analysis of the accuracy of two diagnostic tests used in combination: Application to the ddimer test and the wells score for the diagnosis of deep vein thrombosis. Value in Health 2013;16:619–28. https://doi.org/10.1016/j.jval.2013.02.007.

Gray LJ, Leigh T, Davies MJ, Patel N, Stone M, Bonar M, Badge R, Khunti K. Systematic review of the development, implementation and availability of smart-phone applications for assessing type 2 diabetes risk. Diabetic Medicine 2013;30:758–60. https://doi.org/10.1111/dme.12115.

Mani H, Levy MJ, Davies MJ, Morris DH, Gray LJ, Bankart J, Blackledge H, Khunti K, Howlett TA. Diabetes and cardiovascular events in women with polycystic ovary syndrome: A 20-year retrospective cohort study. Clinical Endocrinology 2013;78:926–34. https://doi.org/10.1111/cen.12068.

Kendrick D, Young B, Mason-Jones AJ, Ilyas N, Achana FA, Cooper NJ, Hubbard SJ, Sutton AJ, Smith S, Wynn P, Mulvaney C, Watson MC, Coupland C. Home safety education and provision of safety equipment for injury prevention (review). Evidence-Based Child Health 2013;8:761–939. https://doi.org/10.1002/ebch.1911.

Harrington JA, Wheeler GM, Sweeting MJ, Mander AP, Jodrell DI. Adaptive designs for dual-agent phase i dose-escalation studies. Nature Reviews Clinical Oncology 2013;10:277–88. https://doi.org/10.1038/nrclinonc.2013.35.

Davies MJ, Gagliardino JJ, Gray LJ, Khunti K, Mohan V, Hughes R. Real-world factors affecting adherence to insulin therapy in patients with type 1 or type 2 diabetes mellitus: A systematic review. Diabetic Medicine 2013;30:512–24. https://doi.org/10.1111/dme.12128.

Henson J, Yates T, Biddle SJ, Edwardson CL, Khunti K, Wilmot EG, Gray LJ, Gorely T, Nimmo MA, Davies MJ. Associations of objectively measured sedentary behaviour and physical activity with markers of cardiometabolic health. Diabetologia 2013;56:1012–20. https://doi.org/10.1007/s00125-013-2845-9.

Ran R, Zhao C, Xu X, Yao G. Improving perfect electronic health records and integrated health information in china: A case on disease management of diabetes. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2013;7798 LNCS:232–43. https://doi.org/10.1007/978-3-642-37899-7_20.

Young T, Towstoless M, Zhang Y, Liu X, He J, Klawonn F, Yao G. Lecture notes in computer science (including subseries lecture notes in artificial intelligence and lecture notes in bioinformatics): Preface. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2013;7798 LNCS:V–VI.

Eloranta S, Lambert PC, Sjob̈erg J, Andersson TM, Bjor̈kholm M, Dickman PW. Temporal trends in mortality from diseases of the circulatory system after treatment for hodgkin lymphoma: A population-based cohort study in sweden (1973 to 2006). Journal of Clinical Oncology 2013;31:1435–41. https://doi.org/10.1200/JCO.2012.45.2714.

Crowther MJ, Abrams KR, Lambert PC. Joint modeling of longitudinal and survival data. Stata Journal 2013;13:165–84.

Tleyjeh IM, Bin Abdulhak AA, Riaz M, Garbati MA, Al-Tannir M, Alasmari FA, AlGhamdi M, Khan AR, Erwin PJ, Sutton AJ, Baddour LM. Correction: The association between histamine 2 receptor antagonist use and clostridium difficile infection: A systematic review and meta-analysis (plos one). PLoS ONE 2013;8: https://doi.org/10.1371/annotation/56f8945c-33f6-45bf-87ce-dd512f7c25b0.

Cvancarova M, Aagnes B, Lambert PC, Møller B, Bray F. Proportion cured models applied to 23 cancer sites in norway. International Journal of Cancer 2013;132:1700–10. https://doi.org/10.1002/ijc.27802.

Gray LJ, Barros H, Raposo L, Khunti K, Davies MJ, Santos AC. The development and validation of the portuguese risk score for detecting type 2 diabetes and impaired fasting glucose. Primary Care Diabetes 2013;7:11–8. https://doi.org/10.1016/j.pcd.2013.01.003.

Wilmot EG, Edwardson CL, Achana FA, Davies MJ, Gorely T, Gray LJ, Khunti K, Yates T, Biddle SJ. Erratum: Sedentary time in adults and the association with diabetes, cardiovascular disease and death: Systematic review and meta-analysis (diabetologia doi: 10.1007/s00125-012-2677-z). Diabetologia 2013;56:942–3. https://doi.org/10.1007/s00125-013-2842-z.

Williams NH, Lewis R, Din NU, Matar HE, Fitzsimmons D, Phillips CJ, Sutton A, Burton K, Hendry M, Nafees S, Wilkinson C. A systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica. European Spine Journal 2013;22:1921–35. https://doi.org/10.1007/s00586-013-2739-z.

Riley RD, Hayden JA, Steyerberg EW, Moons KG, Abrams K, Kyzas PA, Malats N, Briggs A, Schroter S, Altman DG, Hemingway H. Prognosis research strategy (progress) 2: Prognostic factor research. PLoS Medicine 2013;10: https://doi.org/10.1371/journal.pmed.1001380.

Eloranta S, Adolfsson J, Lambert PC, Stattin P, Akre O, Andersson TM-L, Dickman PW. How can we make cancer survival statistics more useful for patients and clinicians: An illustration using localized prostate cancer in sweden. Cancer Causes and Control 2013;24:505–15. https://doi.org/10.1007/s10552-012-0141-5.

Achana FA, Cooper NJ, Dias S, Lu G, Rice SJ, Kendrick D, Sutton AJ. Extending methods for investigating the relationship between treatment effect and baseline risk from pairwise meta-analysis to network meta-analysis. Statistics in Medicine 2013;32:752–71. https://doi.org/10.1002/sim.5539.

Bown MJ, Sweeting MJ, Brown LC, Powell JT, Thompson SG. Surveillance intervals for small abdominal aortic aneurysms: A meta-analysis. JAMA - Journal of the American Medical Association 2013;309:806–13. https://doi.org/10.1001/jama.2013.950.

Rutherford MJ, Møller H, Lambert PC. A comprehensive assessment of the impact of errors in the cancer registration process on 1-and 5-year relative survival estimates. British Journal of Cancer 2013;108:691–8. https://doi.org/10.1038/bjc.2013.12.

Thomasouli M-A, Brady EM, Davies MJ, Hall AP, Khunti K, Morris DH, Gray LJ. The impact of diet and lifestyle management strategies for obstructive sleep apnoea in adults: A systematic review and meta-analysis of randomised controlled trials. Sleep and Breathing 2013;17:925–35. https://doi.org/10.1007/s11325-013-0806-7.

Hinchliffe SR, Lambert PC. Flexible parametric modelling of cause-specific hazards to estimate cumulative incidence functions. BMC Medical Research Methodology 2013;13: https://doi.org/10.1186/1471-2288-13-13.

Hingorani AD, Van Der Windt DA, Riley RD, Abrams K, Moons KG, Steyerberg EW, Schroter S, Sauerbrei W, Altman DG, Hemingway H, Briggs A, Brunner N, Croft P, Hayden J, Kyzas P, Malats N, Peat G, Perel P, Roberts I, Timmis A. Prognosis research strategy (progress) 4: Stratified medicine research. BMJ (Online) 2013;346: https://doi.org/10.1136/bmj.e5793.

Hemingway H, Croft P, Perel P, Hayden JA, Abrams K, Timmis A, Briggs A, Udumyan R, Moons KG, Steyerberg EW, Roberts I, Schroter S, Altman DG, Riley RD, Brunner N, Hingorani AD, Kyzas P, Malats N, Peat G, Sauerbrei W, Van Der Windt D. Prognosis research strategy (progress) 1: A framework for researching clinical outcomes. BMJ (Online) 2013;346: https://doi.org/10.1136/bmj.e5595.

Hinchliffe SR, Abrams KR, Lambert PC. The impact of under and over-recording of cancer on death certificates in a competing risks analysis: A simulation study. Cancer Epidemiology 2013;37:11–9. https://doi.org/10.1016/j.canep.2012.08.012.

Xiong T, Parekh-Bhurke S, Loke YK, Abdelhamid A, Sutton AJ, Eastwood AJ, Holland R, Chen Y-F, Walsh T, Glenny A-M, Song F. Overall similarity and consistency assessment scores are not sufficiently accurate for predicting discrepancy between direct and indirect comparison estimates. Journal of Clinical Epidemiology 2013;66:184–91. https://doi.org/10.1016/j.jclinepi.2012.06.022.

Khunti K, Morris DH, Weston CL, Gray LJ, Webb DR, Davies MJ. Joint prevalence of diabetes, impaired glucose regulation, cardiovascular disease risk and chronic kidney disease in south asians and white europeans. PLoS ONE 2013;8: https://doi.org/10.1371/journal.pone.0055580.

Roloff V, Higgins JP, Sutton AJ. Planning future studies based on the conditional power of a meta-analysis. Statistics in Medicine 2013;32:11–24. https://doi.org/10.1002/sim.5524.

Mavridis D, Sutton A, Cipriani A, Salanti G. A fully bayesian application of the copas selection model for publication bias extended to network meta-analysis. Statistics in Medicine 2013;32:51–66. https://doi.org/10.1002/sim.5494.

Bujkiewicz S, Sutton AJ, Abrams KR, Cooper NJ, Spiegelhalter DJ. Transparent interactive decision interrogator - reply to letter to the editor by michael coory. Value in Health 2013;16:216–7. https://doi.org/10.1016/j.jval.2012.10.014.

Crowther MJ, Lambert PC. Stgenreg: A stata package for general parametric survival analysis. Journal of Statistical Software 2013;53:1–17. https://doi.org/10.18637/jss.v053.i12.

Tincello DG, Owen RK, Slack MC, Abrams KR. Validation of the patient global impression scales for use in detrusor overactivity: Secondary analysis of the relax study. BJOG: An International Journal of Obstetrics and Gynaecology 2013;120:212–6. https://doi.org/10.1111/1471-0528.12069.

Sweeting M, Mander A, Sabin T. Bcrm: Bayesian continual reassessment method designs for phase i dose-finding trials. Journal of Statistical Software 2013;54:1–26. https://doi.org/10.18637/jss.v054.i13.

Carter P, Gray LJ, Morris DH, Davies MJ, Khunti K. South asian individuals at high risk of type 2 diabetes have lower plasma vitamin c levels than white europeans. Journal of Nutritional Science 2013;2:1–5. https://doi.org/10.1017/jns.2013.15.

Gibbon S, Huband N, Bujkiewicz S, Hollin CR, Clarke M, Davies S, Duggan C. The influence of admission characteristics on outcome: Evidence from a medium secure forensic cohort. Personality and Mental Health 2013;7:1–10. https://doi.org/10.1002/pmh.1191.

Carter P, Gray LJ, Talbot D, Morris DH, Khunti K, Davies MJ. Fruit and vegetable intake and the association with glucose parameters: A cross-sectional analysis of the let’s prevent diabetes study. European Journal of Clinical Nutrition 2013;67:12–7. https://doi.org/10.1038/ejcn.2012.174.

Mostafa SA, Khunti K, Kilpatrick ES, Webb D, Srinivasan BT, Gray LJ, Davies MJ. Diagnostic performance of using one- or two-hba1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population. Diabetes and Vascular Disease Research 2013;10:84–92. https://doi.org/10.1177/1479164112451473.

Thompson SG, Brown LC, Sweeting MJ, Bown MJ, Kim LG, Glover MJ, Buxton MJ, Powell JT. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: Implications for surveillance intervals and their cost-effectiveness. Health Technology Assessment (Winchester, England) 2013;17:1–118. https://doi.org/10.3310/hta17410.

Halligan S, Wooldrage K, Dadswell E, Kralj-Hans I, Von Wagner C, Edwards R, Yao G, Kay C, Burling D, Faiz O, Teare J, Lilford RJ, Morton D, Wardle J, Atkin W. Computed tomographic colonography versus barium enema for diagnosis of colorectal cancer or large polyps in symptomatic patients (siggar): A multicentre randomised trial. The Lancet 2013;381:1185–93. https://doi.org/10.1016/S0140-6736(12)62124-2.

Atkin W, Dadswell E, Wooldrage K, Kralj-Hans I, Von Wagner C, Edwards R, Yao G, Kay C, Burling D, Faiz O, Teare J, Lilford RJ, Morton D, Wardle J, Halligan S. Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (siggar): A multicentre randomised trial. The Lancet 2013;381:1194–202. https://doi.org/10.1016/S0140-6736(12)62186-2.

Crowther MJ, Abrams KR, Lambert PC. Flexible parametric joint modelling of longitudinal and survival data. Statistics in Medicine 2012;31:4456–71. https://doi.org/10.1002/sim.5644.

Saramago P, Sutton AJ, Cooper NJ, Manca A. Mixed treatment comparisons using aggregate and individual participant level data. Statistics in Medicine 2012;31:3516–36. https://doi.org/10.1002/sim.5442.

Tleyjeh IM, Bin Abdulhak AA, Riaz M, Alasmari FA, Garbati MA, AlGhamdi M, Khan AR, Tannir MA, Erwin PJ, Ibrahim T, AlLehibi A, Baddour LM, Sutton AJ. Association between proton pump inhibitor therapy and clostridium difficile infection: A contemporary systematic review and meta-analysis. PLoS ONE 2012;7: https://doi.org/10.1371/journal.pone.0050836.

Crowther MJ, Lambert PC. Simulating complex survival data. Stata Journal 2012;12:674–87.

Crowther MJ, Langan D, Sutton AJ. Graphical augmentations to the funnel plot to assess the impact of a new study on an existing meta-analysis. Stata Journal 2012;12:605–22.

Andersson TM-L, Lambert PC. Fitting and modeling cure in population-based cancer studies within the framework of flexible parametric survival models. Stata Journal 2012;12:623–38.

Shack LG, Shah A, Lambert PC, Rachet B. Cure by age and stage at diagnosis for colorectal cancer patients in north west england, 1997-2004: A population-based study. Cancer Epidemiology 2012;36:548–53. https://doi.org/10.1016/j.canep.2012.06.011.

Yao GL, Novielli N, Manaseki-Holland S, Chen Y-F, Van Der Klink M, Barach P, Chilton PJ, Lilford RJ. Evaluation of a predevelopment service delivery intervention: An application to improve clinical handovers. BMJ Quality and Safety 2012;21:i29–38. https://doi.org/10.1136/bmjqs-2012-001210.

Gray LJ, Khunti K, Edwardson C, Goldby S, Henson J, Morris DH, Sheppard D, Webb D, Williams S, Yates T, Davies MJ. Implementation of the automated leicester practice risk score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance. Diabetologia 2012;55:3238–44. https://doi.org/10.1007/s00125-012-2725-8.

Ferreira ML, Herbert RD, Crowther MJ, Verhagen A, Sutton AJ. When is a further clinical trial justified? BMJ (Online) 2012;345: https://doi.org/10.1136/bmj.e5913.

Cohen A, Drost P, Marchant N, Mitchell S, Orme M, Rublee D, Simon TA, Sutton A. The efficacy and safety of pharmacological prophylaxis of venous thromboembolism following elective knee or hip replacement: Systematic review and network meta-analysis. Clinical and Applied Thrombosis/Hemostasis 2012;18:611–27. https://doi.org/10.1177/1076029612437579.

Sprigg N, Gray LJ, Bath PM, Christensen H, De Deyn PP, Leys D, O’Neill D, Ringelstein EB. Quality of life after ischemic stroke varies in western countries: Data from the tinzaparin in acute ischaemic stroke trial (taist). Journal of Stroke and Cerebrovascular Diseases 2012;21:587–93. https://doi.org/10.1016/j.jstrokecerebrovasdis.2011.01.007.

Kendrick D, Young B, Mason-Jones AJ, Ilyas N, Achana FA, Cooper NJ, Hubbard SJ, Sutton AJ, Smith S, Wynn P, Mulvaney CA, Watson MC, Coupland C. Home safety education and provision of safety equipment for injury prevention. Cochrane Database of Systematic Reviews 2012;2012: https://doi.org/10.1002/14651858.CD005014.pub3.

Khunti K, Gillies CL, Taub NA, Mostafa SA, Hiles SL, Abrams KR, Davies MJ. A comparison of cost per case detected of screening strategies for type 2 diabetes and impaired glucose regulation: Modelling study. Diabetes Research and Clinical Practice 2012;97:505–13. https://doi.org/10.1016/j.diabres.2012.03.009.

Tincello DG, Kenyon S, Abrams KR, Mayne C, Toozs-Hobson P, Taylor D, Slack M. Botulinum toxin a versus placebo for refractory detrusor overactivity in women: A randomised blinded placebo-controlled trial of 240 women (the relax study). European Urology 2012;62:507–14. https://doi.org/10.1016/j.eururo.2011.12.056.

Sanatinia R, Barrett B, Byford S, Dean M, Green J, Jones R, Leurent B, Lingford-Hughes A, Sweeting M, Touquet R, Tyrer P, Ward H, Crawford MJ. Brief intervention for alcohol misuse in people attending sexual health clinics: Study protocol for a randomized controlled trial. Trials 2012;13: https://doi.org/10.1186/1745-6215-13-149.

Phillips B, Wade R, Westwood M, Riley R, Sutton AJ. Systematic review and meta-analysis of the value of clinical features to exclude radiographic pneumonia in febrile neutropenic episodes in children and young people. Journal of Paediatrics and Child Health 2012;48:641–8. https://doi.org/10.1111/j.1440-1754.2011.02211.x.

Mostafa SA, Davies MJ, Webb DR, Srinivasan BT, Gray LJ, Khunti K. Independent effect of ethnicity on glycemia in south asians and white europeans. Diabetes Care 2012;35:1746–8. https://doi.org/10.2337/dc11-2079.

Webb DR, Khunti K, Lacy P, Gray LJ, Mostafa S, Talbot D, Williams B, Davies MJ. Conduit vessel stiffness in british south asians of indian descent relates to 25-hydroxyvitamin d status. Journal of Hypertension 2012;30:1588–96. https://doi.org/10.1097/HJH.0b013e328354f385.

Sackley CM, Burton CR, Herron-Marx S, Lett K, Mant J, Roalfe AK, Sharp LJ, Sheehan B, Stant KE, Walker MF, Watkins CL, Wheatley K, Williams J, Yao GL, Feltham MG. A cluster randomised controlled trial of an occupational therapy intervention for residents with stroke living in uk care homes (otch): Study protocol. BMC Neurology 2012;12: https://doi.org/10.1186/1471-2377-12-52.

Saramago P, Manca A, Sutton AJ. Deriving input parameters for cost-effectiveness modeling: Taxonomy of data types and approaches to their statistical synthesis. Value in Health 2012;15:639–49. https://doi.org/10.1016/j.jval.2012.02.009.

Moreno SG, Sutton AJ, Thompson JR, Ades AE, Abrams KR, Cooper NJ. A generalized weighting regression-derived meta-analysis estimator robust to small-study effects and heterogeneity. Statistics in Medicine 2012;31:1407–17. https://doi.org/10.1002/sim.4488.

Eloranta S, Lambert PC, Andersson TM, Czene K, Hall P, Björkholm M, Dickman PW. Partitioning of excess mortality in population-based cancer patient survival studies using flexible parametric survival models. BMC Medical Research Methodology 2012;12: https://doi.org/10.1186/1471-2288-12-86.

Khunti K, Gray LJ, Skinner T, Carey ME, Realf K, Dallosso H, Fisher H, Campbell M, Heller S, Davies MJ. Effectiveness of a diabetes education and self management programme (desmond) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care. BMJ (Online) 2012;344: https://doi.org/10.1136/bmj.e2333.

Gray LJ, Cooper N, Dunkley A, Warren FC, Ara R, Abrams K, Davies MJ, Khunti K, Sutton A. A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity. Obesity Reviews 2012;13:483–98. https://doi.org/10.1111/j.1467-789X.2011.00981.x.

Hawkins N, Richardson G, Sutton AJ, Cooper NJ, Griffiths C, Rogers A, Bower P. Surrogates, meta-analysis and cost-effectiveness modelling: A combined analytic approach. Health Economics 2012;21:742–56. https://doi.org/10.1002/hec.1741.

Yates T, Davies MJ, Henson J, Troughton J, Edwardson C, Gray LJ, Khunti K. Walking away from type 2 diabetes: Trial protocol of a cluster randomised controlled trial evaluating a structured education programme in those at high risk of developing type 2 diabetes. BMC Family Practice 2012;13: https://doi.org/10.1186/1471-2296-13-46.

Hinchliffe SR, Rutherford MJ, Crowther MJ, Nelson CP, Lambert PC. Should relative survival be used with lung cancer data? British Journal of Cancer 2012;106:1854–9. https://doi.org/10.1038/bjc.2012.182.

Gray LJ, Khunti K, Williams S, Goldby S, Troughton J, Yates T, Gray A, Davies MJ, Farooqi A, Carey M, Abrams K, Skinner T, Tuomilehto J, Heller S, Samani N, Stribling B, Jones B. Let’s prevent diabetes: Study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic uk population with screen detected impaired glucose regulation. Cardiovascular Diabetology 2012;11: https://doi.org/10.1186/1475-2840-11-56.

Warren FC, Abrams KR, Golder S, Sutton AJ. Systematic review of methods used in meta-analyses where a primary outcome is an adverse or unintended event. BMC Medical Research Methodology 2012;12: https://doi.org/10.1186/1471-2288-12-64.

Sweeting MJ, Mander AP. Escalation strategies for combination therapy phase i trials. Pharmaceutical Statistics 2012;11:258–66. https://doi.org/10.1002/pst.1497.

Moreno SG, Novielli N, Cooper NJ. Cost-effectiveness of the implantable heartmate ii left ventricular assist device for patients awaiting heart transplantation. Journal of Heart and Lung Transplantation 2012;31:450–8. https://doi.org/10.1016/j.healun.2011.10.017.

Sweeting MJ, Thompson SG, Brown LC, Powell JT. Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms. British Journal of Surgery 2012;99:655–65. https://doi.org/10.1002/bjs.8707.

Edwardson CL, Gorely T, Davies MJ, Gray LJ, Khunti K, Wilmot EG, Yates T, Biddle SJ. Association of sedentary behaviour with metabolic syndrome: A meta-analysis. PLoS ONE 2012;7: https://doi.org/10.1371/journal.pone.0034916.

Morrow DA, Braunwald E, Bonaca MP, Ameriso SF, Dalby AJ, Fish MP, Fox KA, Lipka LJ, Liu X, Nicolau JC, Ophuis AJ, Paolasso E, Scirica BM, Spinar J, Theroux P, Wiviott SD, Strony J, Murphy SA, McCabe CH, Morin S, Lamp J, Gershman E, Deenadayalu N, Skene A, Hill K, Bennett L, Plat F, Berman G, Kilian A, He W, Aylward P, Bassand JP, Betriu A, Bounameaux H, Corbalan R, Creager M, De Ferrari G, Dellborg M, Diehm CH, Dietz R, Goto S, Grande P, Hankey G, Isaza D, Jensen P, Kiss R, Lewis B, Merlini P, Moliterno D, Morais J, Nieminen M, Nilsen D, Olin J, Ophuis TO, Pichler M, Shinohara Y, Teal P, Tendera M, Thomassen L, Van de Werf F, White H, Wilcox R, Alberts M, Diener H, Mohr J, Welch M, Awtry E, Berger C, Desai A, Gelfand E, Ho C, Leeman D, Link M, Norden A, Pande A, Rost N, Ruberg R, Silverman S, Singhal A, Vita J, Frye RL, Bailey KR, Easton J, Hochman J, Steg PG, Verheught F, Lee K, Mauro DO, Centurion A, Carlevaro O, Cardozo E, Cartasegna L, Soccini N, Farras HA, Molina Aguirre E, Duronto E, Arrechavala L, Rey R, Stilman A et al. Vorapaxar in the secondary prevention of atherothrombotic events. New England Journal of Medicine 2012;366:1404–13. https://doi.org/10.1056/NEJMoa1200933.

Welton NJ, Sutton AJ, Cooper NJ, Abrams KR, Ades AE. Evidence synthesis for decision making in healthcare. 2012.

Sweeting MJ, Thompson SG. Making predictions from complex longitudinal data, with application to planning monitoring intervals in a national screening programme. Journal of the Royal Statistical Society Series A: Statistics in Society 2012;175:569–86. https://doi.org/10.1111/j.1467-985X.2011.01005.x.

Hinchliffe SR, Dickman PW, Lambert PC. Adjusting for the proportion of cancer deaths in the general population when using relative survival: A sensitivity analysis. Cancer Epidemiology 2012;36:148–52. https://doi.org/10.1016/j.canep.2011.09.007.

Gray LJ, Davies MJ, Hiles S, Taub NA, Webb DR, Srinivasan BT, Khunti K. Detection of impaired glucose regulation and/or type 2 diabetes mellitus, using primary care electronic data, in a multiethnic uk community setting. Diabetologia 2012;55:959–66. https://doi.org/10.1007/s00125-011-2432-x.

Webb DR, Khunti K, Gray LJ, Srinivasan BT, Farooqi A, Wareham N, Griffin SC, Davies MJ. Intensive multifactorial intervention improves modelled coronary heart disease risk in screen-detected type2 diabetes mellitus: A cluster randomized controlled trial. Diabetic Medicine 2012;29:531–40. https://doi.org/10.1111/j.1464-5491.2011.03441.x.

Sutaria S, Philipson P, Fitzpatrick NK, Abrams K, Moreno SG, Timmis A, Hingorani AD, Hemingway H. Translational phases of evidence in a prognostic biomarker: A systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease. Heart 2012;98:615–22. https://doi.org/10.1136/heartjnl-2011-300862.

Crowther MJ, Riley RD, Staessen JA, Wang J, Gueyffier F, Lambert PC. Individual patient data meta-analysis of survival data using poisson regression models. BMC Medical Research Methodology 2012;12: https://doi.org/10.1186/1471-2288-12-34.

Andrae B, Andersson TM-L, Lambert PC, Kemetli L, Silfverdal L, Strander B, Ryd W, Dillner J, Törnberg S, Sparén P. Screening and cervical cancer cure: Population based cohort study. BMJ (Online) 2012;344: https://doi.org/10.1136/bmj.e900.

Mander AP, Wason JM, Sweeting MJ, Thompson SG. Admissible two-stage designs for phase ii cancer clinical trials that incorporate the expected sample size under the alternative hypothesis. Pharmaceutical Statistics 2012;11:91–6. https://doi.org/10.1002/pst.501.

Phillips RS, Sutton AJ, Riley RD, Chisholm JC, Picton SV, Stewart LA. Predicting infectious complications in neutropenic children and young people with cancer (ipd protocol). Systematic Reviews 2012;1: https://doi.org/10.1186/2046-4053-1-8.

Turner RM, Lloyd-Jones M, Anumba DO, Smith GC, Spiegelhalter DJ, Squires H, Stevens JW, Sweeting MJ, Urbaniak SJ, Webster R, Thompson SG. Routine antenatal anti-d prophylaxis in women who are rh(D) negative: Meta-analyses adjusted for differences in study design and quality. PLoS ONE 2012;7: https://doi.org/10.1371/journal.pone.0030711.

Rutherford MJ, Dickman PW, Lambert PC. Comparison of methods for calculating relative survival in population-based studies. Cancer Epidemiology 2012;36:16–21. https://doi.org/10.1016/j.canep.2011.05.010.

Peters JL, Moreno SG, Phillips B, Sutton AJ. Are we sure about the evidence for zinc in prophylaxis of the common cold? Expert Review of Respiratory Medicine 2012;6:15–6. https://doi.org/10.1586/ers.11.84.

Holmberg L, Robinson D, Sandin F, Bray F, Linklater KM, Klint Å, Lambert PC, Adolfsson J, Hamdy FC, Catto J, Møller H. A comparison of prostate cancer survival in england, norway and sweden: A population-based study. Cancer Epidemiology 2012;36:e7–e12. https://doi.org/10.1016/j.canep.2011.08.001.

Ahmed I, Sutton AJ, Riley RD. Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: A database survey. BMJ (Online) 2012;344: https://doi.org/10.1136/bmj.d7762.

Ara R, Blake L, Gray L, Hernández M, Crowther M, Dunkley A, Warren F, Jackson R, Rees A, Stevenson M, Abrams K, Cooper N, Davies M, Khunti K, Sutton A. What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A systematic review. Health Technology Assessment 2012;16: https://doi.org/10.3310/hta16050.

Cooper NJ, Kendrick D, Achana F, Dhiman P, He Z, Wynn P, Le Cozannet E, Saramago P, Sutton AJ. Network meta-analysis to evaluate the effectiveness of interventions to increase the uptake of smoke alarms. Epidemiologic Reviews 2012;34:32–45. https://doi.org/10.1093/epirev/mxr015.

Kendrick D, Maula A, Stewart J, Clacy R, Coffey F, Cooper N, Coupland C, Hayes M, McColl E, Reading R, Sutton A, Towner EM, Watson MC. Keeping children safe at home: Protocol for three matched case-control studies of modifiable risk factors for falls. Injury Prevention 2012;18:1–7. https://doi.org/10.1136/injuryprev-2012-040394.

Langan D, Higgins JP, Gregory W, Sutton AJ. Graphical augmentations to the funnel plot assess the impact of additional evidence on a meta-analysis. Journal of Clinical Epidemiology 2012;65:511–9. https://doi.org/10.1016/j.jclinepi.2011.10.009.

Cepeda MS, Sutton A, Weinstein R, Kim M. Effect of tapentadol extended release on productivity: Results from an analysis combining evidence from multiple sources. Clinical Journal of Pain 2012;28:8–13. https://doi.org/10.1097/AJP.0b013e3182201983.

Dunkley AJ, Charles K, Gray LJ, Camosso-Stefinovic J, Davies MJ, Khunti K. Effectiveness of interventions for reducing diabetes and cardiovascular disease risk in people with metabolic syndrome: Systematic review and mixed treatment comparison meta-analysis. Diabetes, Obesity and Metabolism 2012;14:616–25. https://doi.org/10.1111/j.1463-1326.2012.01571.x.

Burton JO, Gray LJ, Webb DR, Davies MJ, Khunti K, Crasto W, Carr SJ, Brunskill NJ. Association of anthropometric obesity measures with chronic kidney disease risk in a non-diabetic patient population. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association 2012;27:1860–6. https://doi.org/10.1093/ndt/gfr574.

Wilmot EG, Edwardson CL, Achana FA, Davies MJ, Gorely T, Gray LJ, Khunti K, Yates T, Biddle SJ. Sedentary time in adults and the association with diabetes, cardiovascular disease and death: Systematic review and meta-analysis. Diabetologia 2012;55:2895–905. https://doi.org/10.1007/s00125-012-2677-z.

Møller H, Sandin F, Robinson D, Bray F, Klint S, Linklater KM, Lambert PC, Phlman L, Holmberg L, Morris E. Colorectal cancer survival in socioeconomic groups in england: Variation is mainly in the short term after diagnosis. European Journal of Cancer 2012;48:46–53. https://doi.org/10.1016/j.ejca.2011.05.018.

Cepeda MS, Fife D, Lobanov V, Sutton A. Can soccer predictions boost the use of indirect comparison to assess the safety of drugs? Open Drug Safety Journal 2011;2:25–8. https://doi.org/10.2174/1876818001102010025.

Karkos CD, Sutton AJ, Bown MJ, Sayers RD. A meta-analysis and metaregression analysis of factors influencing mortality after endovascular repair of ruptured abdominal aortic aneurysms. European Journal of Vascular and Endovascular Surgery 2011;42:775–86. https://doi.org/10.1016/j.ejvs.2011.07.028.

Sackley C, Hoppitt TJ, Calvert M, Gill P, Eaton B, Yao G, Pall H. Huntington’s disease: Current epidemiology and pharmacological management in uk primary care. Neuroepidemiology 2011;37:216–21. https://doi.org/10.1159/000331912.

Benhalima K, Song SH, Wilmot EG, Khunti K, Gray LJ, Lawrence I, Davies M. Characteristics, complications and management of a large multiethnic cohort of younger adults with type 2 diabetes. Primary Care Diabetes 2011;5:245–50. https://doi.org/10.1016/j.pcd.2011.06.003.

Lambert PC, Holmberg L, Sandin F, Bray F, Linklater KM, Purushotham A, Robinson D, Møller H. Quantifying differences in breast cancer survival between england and norway. Cancer Epidemiology 2011;35:526–33. https://doi.org/10.1016/j.canep.2011.04.003.

Grutters JP, Abrams KR, Ruysscher D de, Pijls-Johannesma M, Peters HJ, Beutner E, Lambin P, Joore MA. When to wait for more evidence? Real options analysis in proton therapy. Oncologist 2011;16:1752–61. https://doi.org/10.1634/theoncologist.2011-0029.

Moreno SG, Sutton AJ, Ades AE, Cooper NJ, Abrams KR. Adjusting for publication biases across similar interventions performed well when compared with gold standard data. Journal of Clinical Epidemiology 2011;64:1230–41. https://doi.org/10.1016/j.jclinepi.2011.01.009.

Gray LJ, Yates T, Davies MJ, Brady E, Webb DR, Sattar N, Khunti K. Defining obesity cut-off points for migrant south asians. PLoS ONE 2011;6: https://doi.org/10.1371/journal.pone.0026464.

Song F, Xiong T, Parekh-Bhurke S, Loke YK, Sutton AJ, Eastwood AJ, Holland R, Chen Y-F, Glenny A-M, Deeks JJ, Altman DG. Inconsistency between direct and indirect comparisons of competing interventions: Meta-epidemiological study. BMJ (Online) 2011;343: https://doi.org/10.1136/bmj.d4909.

Sweeting MJ, Thompson SG. Joint modelling of longitudinal and time-to-event data with application to predicting abdominal aortic aneurysm growth and rupture. Biometrical Journal 2011;53:750–63. https://doi.org/10.1002/bimj.201100052.

Epstein D, Sutton A. Modelling correlated clinical outcomes in health technology appraisal. Value in Health 2011;14:793–9. https://doi.org/10.1016/j.jval.2011.04.007.

Hakulinen T, Seppä K, Lambert PC. Choosing the relative survival method for cancer survival estimation. European Journal of Cancer 2011;47:2202–10. https://doi.org/10.1016/j.ejca.2011.03.011.

Webb DR, Gray LJ, Khunti K, Srinivasan B, Taub N, Campbell S, Barnett J, Farooqi A, Echouffo-Tcheugui JB, Griffin SJ, Wareham NJ, Davies MJ. Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: The addition-leicester study. Diabetologia 2011;54:2237–46. https://doi.org/10.1007/s00125-011-2189-2.

Crasto W, Jarvis J, Khunti K, Skinner TC, Gray LJ, Brela J, Troughton J, Daly H, Lawrence IG, McNally PG, Carey ME, Davies MJ. Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The microalbuminuria education and medication optimisation (memo) study. Diabetes Research and Clinical Practice 2011;93:328–36. https://doi.org/10.1016/j.diabres.2011.05.008.

Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, Lau J, Carpenter J, Rücker G, Harbord RM, Schmid CH, Tetzlaff J, Deeks JJ, Peters J, Macaskill P, Schwarzer G, Duval S, Altman DG, Moher D, Higgins JP. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ (Online) 2011;343: https://doi.org/10.1136/bmj.d4002.

Morris EJ, Sandin F, Lambert PC, Bray F, Klint Å, Linklater K, Robinson D, Påhlman L, Holmberg L, Møller H. A population-based comparison of the survival of patients with colorectal cancer in england, norway and sweden between 1996 and 2004. Gut 2011;60:1087–93. https://doi.org/10.1136/gut.2010.229575.

Pickup JC, Freeman SC, Sutton AJ. Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: Meta-analysis of randomised controlled trials using individual patient data. BMJ 2011;343: https://doi.org/10.1136/bmj.d3805.

Coleman MP, Rachet B, Woods L, Berrino F, Butler J, Capocaccia R, Dickman P, Gavin A, Giorgi R, Hamilton W, Lambert P, Peake MD, Perme MP, Stare J, Vedstedt P. Rebuttal to editorial saying cancer survival statistics are misleading. BMJ 2011;343: https://doi.org/10.1136/bmj.d4214.

Bujkiewicz S, Jones HE, Lai MC, Cooper NJ, Hawkins N, Squires H, Abrams KR, Spiegelhalter DJ, Sutton AJ. Development of a transparent interactive decision interrogator to facilitate the decision-making process in health care. Value in Health 2011;14:768–76. https://doi.org/10.1016/j.jval.2010.12.002.

Aujla N, Davies MJ, Skinner TC, Gray LJ, Webb DR, Srinivasan B, Khunti K. The association between anxiety and measures of glycaemia in a population-based diabetes screening programme. Diabetic Medicine 2011;28:785–8. https://doi.org/10.1111/j.1464-5491.2011.03245.x.

Andersson TM, Dickman PW, Eloranta S, Lambert PC. Estimating and modelling cure in population-based cancer studies within the framework of flexible parametric survival models. BMC Medical Research Methodology 2011;11: https://doi.org/10.1186/1471-2288-11-96.

Lodwick R, Alioum A, Archibald C, Birrell P, Commenges D, Costagliola D, De Angeli D, Donoghoe M, Garnett G, Ghys P, Law M, Lundgren J, Ndawinz J, Presanis A, Sabin C, Salminen M, Sommen C, Stanecki K, Stover J, Supervie V, Sweeting M, Van De Laar M, Van Sighem A, Wand H, Wilson D, Yan P, Phillips A. HIV in hiding: Methods and data requirements for the estimation of the number of people living with undiagnosed hiv. AIDS 2011;25:1017–23. https://doi.org/10.1097/QAD.0b013e3283467087.

Powell JT, Sweeting MJ, Brown LC, Gotensparre SM, Fowkes FG, Thompson SG. Systematic review and meta-analysis of growth rates of small abdominal aortic aneurysms. British Journal of Surgery 2011;98:609–18. https://doi.org/10.1002/bjs.7465.

Shah AD, Nicholas O, Timmis AD, Feder G, Abrams KR, Chen R, Hingorani AD, Hemingway H. Threshold haemoglobin levels and the prognosis of stable voronary disease: Two new cohorts and a systematic review and meta-analysis. PLoS Medicine 2011;8: https://doi.org/10.1371/journal.pmed.1000439.

Eaker S, Wigertz A, Lambert PC, Bergkvist L, Ahlgren J, Lambe M. Breast cancer, sickness absence, income and marital status. A study on life situation 1 year prior diagnosis compared to 3 and 5 years after diagnosis. PLoS ONE 2011;6: https://doi.org/10.1371/journal.pone.0018040.

Benhalima K, Wilmot E, Khunti K, Gray LJ, Lawrence I, Davies M. Type 2 diabetes in younger adults: Clinical characteristics, diabetes-related complications and management of risk factors. Primary Care Diabetes 2011;5:57–62. https://doi.org/10.1016/j.pcd.2010.08.001.

Parekh-Bhurke S, Kwok CS, Pang C, Hooper L, Loke YK, Ryder JJ, Sutton AJ, Hing CB, Harvey I, Song F. Uptake of methods to deal with publication bias in systematic reviews has increased over time, but there is still much scope for improvement. Journal of Clinical Epidemiology 2011;64:349–57. https://doi.org/10.1016/j.jclinepi.2010.04.022.

Thomas T, Abrams KR, Subramanian V, Mannath J, Ragunath K. Esophageal stents for benign refractory strictures: A meta-analysis. Endoscopy 2011;43:386–93. https://doi.org/10.1055/s-0030-1256331.

Williams KS, Coleby D, Abrams KR, Turner DA, Shaw C, Assassa RP, Cooper NJ, Donaldson MM, McGrother CW. Long term follow-up of a randomised controlled trial of services for urinary symptoms. BMC Health Services Research 2011;11: https://doi.org/10.1186/1472-6963-11-58.

Webb DR, Gray LJ, Khunti K, Campbell S, Dallosso H, Davies MJ. Contrasting cardiovascular risk profiles and prescribed cardio-protective therapies in newly-diagnosed type 2 diabetes identified through screening and standard practice. Diabetes Research and Clinical Practice 2011;91:280–5. https://doi.org/10.1016/j.diabres.2010.11.021.

Powell JT, Gotensparre SM, Sweeting MJ, Brown LC, Fowkes FG, Thompson SG. Rupture rates of small abdominal aortic aneurysms: A systematic review of the literature. European Journal of Vascular and Endovascular Surgery 2011;41:2–10. https://doi.org/10.1016/j.ejvs.2010.09.005.

Hoppitt T, Pall H, Calvert M, Gill P, Yao G, Ramsay J, James G, Conduit J, Sackley C. A systematic review of the incidence and prevalence of long-term neurological conditions in the uk. Neuroepidemiology 2011;36:19–28. https://doi.org/10.1159/000321712.

Nicholson KG, Abrams KR, Batham S, Clark TW, Hoschler K, Lim WS, Medina M-J, Nguyen-Van-Tam JS, Read RC, Warren FC, Zambon M. Immunogenicity and safety of a two-dose schedule of whole-virion and as03a-adjuvanted 2009 influenza a (h1n1) vaccines: A randomised, multicentre, age-stratified, head-to-head trial. The Lancet Infectious Diseases 2011;11:91–101. https://doi.org/10.1016/S1473-3099(10)70296-6.

Morden JP, Lambert PC, Latimer N, Abrams KR, Wailoo AJ. Assessing methods for dealing with treatment switching in randomised controlled trials: A simulation study. BMC Medical Research Methodology 2011;11: https://doi.org/10.1186/1471-2288-11-4.

Cooper NJ, Peters J, Lai MC, Juni P, Wandel S, Palmer S, Paulden M, Conti S, Welton NJ, Abrams KR, Bujkiewicz S, Spiegelhalter D, Sutton AJ. How valuable are multiple treatment comparison methods in evidence-based health-care evaluation. Value in Health 2011;14:371–80. https://doi.org/10.1016/j.jval.2010.09.001.

Rodgers M, Epstein D, Bojke L, Yang H, Craig D, Fonseca T, Myers L, Bruce I, Chalmers R, Bujkiewicz S, Lai M, Cooper N, Abrams K, Spiegelhalter D, Sutton A, Sculpher M, Woolacott N. Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis: A systematic review and economic evaluation. Health Technology Assessment 2011;15:134. https://doi.org/10.3310/hta15100.

Ibrahim T, Qureshi A, Sutton AJ, Dias JJ. Surgical versus nonsurgical treatment of acute minimally displaced and undisplaced scaphoid waist fractures: Pairwise and network meta-analyses of randomized controlled trials. Journal of Hand Surgery 2011;36:1759–1768.e1. https://doi.org/10.1016/j.jhsa.2011.08.033.

Lewis R, Williams N, Matar H, Din N, Fitzsimmons D, Phillips C, Jones M, Sutton A, Burton K, Nafees S, Hendry M, Rickard I, Chakraverty R, Wilkinson C. The clinical effectiveness and cost-effectiveness of management strategies for sciatica: Systematic review and economic model. Health Technology Assessment 2011;15:iii–303. https://doi.org/10.3310/hta15390.