Professor Julian Barwell

Professor in Genomic Medicine

School/Department: Genetics and Genome Biology, Department of

Telephone: +44 (0)116 258 6042



Julian Barwell trained in Medicine at Guy's and St Thomas' Hospitals in London (1991-1997: Distinction in Medicine and intercalated BSc in Basic Medical Sciences and Human Genetics). He was a junior doctor in South London and became a Member of the Royal College of Physicians in 2000. He completed his PhD in familial breast cancer susceptibility in 2006.

After finishing his Clinical Genetics training (2001-2007) at Guy's, St George's and the Royal Marsden from the University of London; he started as a consultant in Clinical Genetics in Leicester. He runs specialist clinics in: inherited cancer susceptibility; non-alcoholic fatty liver disease and susceptibility to hepatitis, cirrhosis and hepatocellular carcinoma; Von Hipped Linda syndrome and Neurofibromatosis type 2. He has over 60 publications and helped coin the internationally known phrase, the 'Angelina Jolie effect' on referrals to inherited breast cancer clinics. He developed the first You Tube channel for Clinical Genetics that has been viewed in over 100 countries and developed the Supporting Families with Cancer projects in association with the Genetics Education Centre (GENIE) at the University of Leicester. This has included a universal triage system and familial bowel cancer management computer model. 

He is the clinical lead for the delivery of Paediatrics, Obstetrics & Gynaecology, Non-Malignant Haematology and Clinical Genetics national portfolio research studies (CRN) in the East Midlands, covering 4.5 million people across 15 hospital trusts. He is the rare disease lead for the 100,000 Genome Project in Leicester and the public and patient involvement clinical lead for the East of England Genomics Medicine Centre with the aim of reducing inequality of access to Genomic Medicine. He is the designer of the genome project eligibility criteria wheels for Health Education England and is on the Genomics England committee for patient involvement and access to genomics for black and minority ethnic groups. He is a national clinical advisor to the National Hereditary Breast Cancer Helpline and helped develop the award winning Prostaid male health App and is clinical lead of the United Against Prostate Cancer project, establishing tumour BRCA testing. He is joint clinical lead of the Paediatric and Genetics Clinical Research Facility at the Leicester Royal infirmary and is establishing a fragile X syndrome research group and patient self-navigation App project with the Genomic Medicine Service Alliance.

He is a senior author of the newly commissioned book Clinical Genetics and Genomics at a Glance as well as a children's book on DNA. He was awarded an honorary chair (professorship) by the University of Leicester in 2015.


  • A) Shared digital and genomic platform research including:
    • 1. Previvorship in the digital Age
    • 2. Previvorship and survivorship in thoracic aortic dissection
    • 3. Previvorship in Lynch Syndrome
  • B) Prostate tumour sequencing and community engagement in prostate cancer
  • C) Fragile X interventional research studies 


Barwell et al The dawn of genomic medicine: the role of the 100,000 Genome Project Oncology Central 2016

Barwell and Kumar Genomic Testing and Genomic Care: Are They Talking to Each Other? Journal of Clinical Research and Bioethics 6 (6) (2015)

Jones G et al Dr J Barwell senior author. Developing and assessing the utility of a You-Tube based clinical genetics video channel for families affected by inherited tumours. Fam Cancer. 2016 Apr;15(2):351-5. doi: 10.1007/s10689-016-9866-8.

Pal et al. Dr J Barwell senior author Immunocytochemical detection of ERG expression in exfoliated urinary cells identifies patients with prostate cancer with high specificity. BJU Int. 2016 Apr;117(4):686-96. doi: 10.1111/bju.13184. Epub 2015 Jul 29.

Browning M et al Dr J Barwell senior author Cowden's and immunodeficiency. Journal of Medical Genetics J Med Genet. 2015 Aug 5.

Craft et al. Dr J Barwell Senior author. Supporting families with Cancer: A patient centred survivorship model of care. 2015 familial Cancer 2015 Jun 16.

D Gareth Evans, Julian Barwell, Diana M Eccles, Amanda Collins, Louise Izatt, Chris Jacobs, Alan Donaldson, Angela F Brady, Andrew Cuthbert, Rachel Harrison, Sue Thomas, Anthony Howell, FH02 Study Group; RGC teams; Zosia Miedzybrodzka, Alex Murray. The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services Breast Cancer Res. 2014 Sep 19;16(5):442. 


Shared digital genomic projects.


Medicine Medical Genetics Community groups/schools and Postgraduate.

Press and media

Familial cancer Fragile X syndrome and digital/genomics solutions to build innovative 21st century Healthcare solutions.

Media coverage

A number of radio broadcasts on genomic testing and my Facebook COVID diary when I returned to the wards after a nineteen year break. This covers my feelings and also explains genomic medicine in every day language.


BSc, MBBS, FRCP (UK), PhD, AFHEA, and honorary professorship.

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