Statistical Computing and Inference
Module code: MD7453
This module provides an overview of approaches to statistical inference, both likelihood and Bayesian, applied to medical/health data and the use of statistical software packages.
Statistical computing
You will be introduced, through an introductory lecture and self-learning guide, to basic data handling skills using the command languages of R and Python and will have the opportunity to apply these skills.
Topics covered may include:
Writing clearly annotated and replicable programs in the course software, R and Python, for:
- Data entry
- Data manipulation
- Data analysis
- Graphs
- Automation of routine tasks
Statistical inference
We will introduce the different approaches to statistical inference and contrasts the traditional approach to statistics based on repeated sampling with the likelihood and Bayesian approaches. The theoretical application of those ideas requires a basic knowledge of algebra and calculus and programming is an important aspect.
Topics covered may include:
- Likelihood, maximum likelihood estimate (MLE) and the information
- Log likelihood curves and support intervals
- MLE and the observed information for simple distributions
- Bayes' theorem for both binary and general quantities
- The nature and source of prior distributions and how to interpret posterior distributions
- Conjugate models and predictions
- Introduction to WinBUGS and Markov chain Monte Carlo (MCMC)
- Comparison and contrast of the different approaches to statistical inference