Pathophysiology of Disease

Module code: MB2080

‘Pathophysiology of disease’ will provide an introduction on how physiological systems function in health and disease, and on the significance of various disease states in terms of symptoms, prevalence, morbidity, mortality, risk factors and prevention strategies. Emphasis will be made on understanding the functional changes that accompany a particular syndrome or disease (pathophysiology) and on the physiological and biochemical basis of current and possible future therapies. Lectures will address the normal underlying physiology of the system before covering how malfunction can result in disease. Etiological and epidemiological perspectives of various disease states will also be covered, as will the physiology and biochemistry underlying current and possible future treatment strategies.

Topics covered:

• Gastrointestinal system 
• Mitochondrial physiology and disease 
• Adrenal physiology and disease 
• Cystic fibrosis 
• Liver function and disease 
• Sleep disorders
• Reproduction and infertility