Using spectral analysis of intra-cardiac electrocardiograms of patients undergoing radio-frequency ablation of persistent atrial fibrillation coupled with 3-D mapping we have demonstrated heterogeneous responses to ablation across the atria. This work has identified specific critical sites where ablation might improve the success and longer term outcome of this interventional procedure.
Catheter Robotics – In collaboration with an industrial partner, Professor André Ng carried out the first in man evaluation of a novel remote catheter manipulation system for electrophysiological studies. This attracted world-wide media interest. Subsequently, in a Phase 1/II study we are now evaluating its feasibility and safety utility for catheter-based atrial flutter ablation.