Dr Xin Li

I am a Lecturer in Biomedical Engineering jointly appointed at the School of Engineering and Department of Cardiovascular Sciences.

I obtained BEng in Electrical Information Engineering from the University of Science and Technology Beijing 2011 and MSc in Electrical Electronic Engineering from the University of Leeds in 2012. I completed my PhD in Biomedical Engineering from the University of Leicester in 2016. I worked as Research Associate from 2016 and Lecturer from October 2019. 

Research Interests

My research interest focuses on digital signal processing and intelligent algorithms of biological and biomedical signals:

Improving target identification for catheter ablation using advanced signal processing techniques and intelligent algorithms for human persistent atrial fibrillation

Algorithms development for novel ECG risk makers for sudden cardiac death

Machine learning Classification and Regression

Recurrent Quantification Analysis

Mapping and Cardiac Arrythmias

Body surface potential mapping

Electrocardiogram (ECG) analysis

Wearable Medical Devices and remote monitoring

2024

• Long Chen; Zheheng Jiang; Joseph Barker; Huiyu Zhou; Fernando S. Schlindwein; Will Nicolson; G. Andre Ng; Xin Li., "ECGVEDNET: A Variational Encoder-Decoder Network for ECG Delineation in Morphology Variant ECGs," in IEEE Transactions on Biomedical Engineering, doi: 10.1109/TBME.2024.3363077.

• Joseph Barker*, Xin Li*, Ahmed Kotb, Akash Mavilakandy, Ibrahim Antoun, Chokanan Thaitirarot, Ivelin Koev, Sharon Man, Fernando S Schlindwein, Harshil Dhutia, Shui Hao Chin, Ivan Tyukin, William B Nicolson, G Andre Ng, Artificial intelligence for ventricular arrhythmia capability using ambulatory electrocardiograms, European Heart Journal - Digital Health, 2024;, ztae004, https://doi.org/10.1093/ehjdh/ztae004

2023

• X. Li, F. S. Schlindwein, J. Zhao, M. Bishop, and G. A. Ng, "Editorial: Exploring mechanisms of cardiac rhythm disturbances using novel computational methods: Prediction, classification, and therapy," , Frontiers in Physiology, Editorial vol. 14, 2023-February-10 2023, doi: 10.3389/fphys.2023.1155857.

2022

• Joseph Barker, Xin Li, Sarah Khavandi, David Koeckerling, Akash Mavilakandy, Coral Pepper, Vasiliki Bountziouka, Long Chen, Ahmed Kotb, Ibrahim Antoun, John Mansir, Karl Smith-Byrne, Fernando S Schlindwein, Harshil Dhutia, Ivan Tyukin, William B Nicolson, G Andre Ng, Machine learning in sudden cardiac death risk prediction: a systematic review, EP Europace, 2022;, euac135, https://doi.org/10.1093/europace/euac135

• Ehnesh M, Li X, Almeida TP, Chu GS, Dastagir N, Stafford PJ, et al. Evaluating spatial disparities of rotor sites and high dominant frequency regions during catheter ablation for PersAF patients targeting high dominant frequency sites using non-contacting mapping. Front. Physiol, 2022, Vol 13, doi: 10.3389/fphys.2022.946718.

• Chu, G. S*., X. Li*, P. J. Stafford, F. J. Vanheusden, J. L. Salinet, T. P. Almeida, N. Dastagir, A. J. Sandilands, P. Kirchhof, F. S. Schlindwein and G. A. Ng.Simultaneous Whole-Chamber Non-contact Mapping of Highest Dominant Frequency Sites During Persistent Atrial Fibrillation: A Prospective Ablation Study. Front. Physiol, 2022, Vol 13. doi:10.3389/fphys.2022.826449

2021

• Pooranachandran V, Nicolson W, Vali Z, Li X, Ng G. Non-invasive markers for sudden cardiac death risk stratification in dilated cardiomyopathy. Heart,  20 October 2021. doi: 10.1136/heartjnl-2021-319971

• Z. Jiang, F. Zhou, A. Zhao, X. Li, L. Li, D. Tao, X. Li, H. Zhou, "Muti-view Mouse Social Behaviour Recognition with Deep Graphic Model," in IEEE Transactions on Image Processing, 2021, doi: 10.1109/TIP.2021.3083079.

• Li, X., Chu, G.S, Almeida, T.P., Vanheusden F.J., Salinet, J., Dastagir, N., Mistry, A. R., Vali, Z, Sidhu B, Starfford, P. J., Schlindwein, F.S., Ng, G.A., 2021. Automatic Extraction of Recurrent Patterns of High Dominant Frequency Mapping during Human Persistent Atrial Fibrillation. Front. Physiol, 2021 Vol. 12 Issue 286, DOI: 10.3389/fphys.2021.649486

2020

• Almeida, T.; Soriano, D.; Mase, M.; Ravelli, F.; Bezerra, A.; Li, X.; Chu, G.; Salinet, J.; Stafford, P.; Andre Ng, G.; Schlindwein, F.; Yoneyama, T. Unsupervised Classification of Atrial Electrograms for Electroanatomic Mapping of Human Persistent Atrial Fibrillation. IEEE Transactions on Biomedical Engineering 2020, 1–1. https://doi.org/10.1109/TBME.2020.3021480.

• Li, X., Almeida, T.P., Dastagir, N., Guillem, M.S., Salinet, J., Chu, G.S., Stafford, P.J., Schlindwein, F.S., Ng, G.A., 2020. Standardizing Single-Frame Phase Singularity Identification Algorithms and Parameters in Phase Mapping During Human Atrial Fibrillation. Front. Physiol. 11, 869. doi: doi.org/10.3389/fphys.2020.00869

• Almeida, T.P., Li, X., Soriano, D.C., Schlindwein, F.S. and Ng, G.A. (2020), Pitfalls in the definition of complex fractionated atrial electrograms for atrial fibrillation studies. J Cardiovasc Electrophysiol, 31: 373-374. doi:10.1111/jce.14302

• Mistry A, Vali Z, Sidhu B, Budgeon C, Yuyun MF, Pooranachandran V, Li X, Newton M, Watts J, Khunti K, Samani NJ and Ng GA. Disparity in implantable cardioverter defibrillator therapy among minority South Asians in the United Kingdom. Heart. 2020:heartjnl-2019-315978.

2019 and before

• O’Shea, Holmes, Yu, Winter, Wells, Correia, Boukens, Chu, Li, Ng, Kirchhof, Fabritz, Rajpoot, Pavlovic, ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology, Scientific Reports - Nature 2019;9:1389.

• Vanheusden FJ, Chu GS, Li X, Salinet J, Almeida TP, Dastagir N, et al. Systematic differences of non-invasive dominant frequency estimation compared to invasive dominant frequency estimation in atrial fibrillation.Comput Biol Med. 2019;104:299-309.

• Mistry, A, Vali, Z, Taher, A, Sidhu, B, Li, X, Newton, M, & Ng, G. A (2019). Consideration for primary prevention implantable cardioverter defibrillators differ between specialities.Postgraduate Medical Journal, 95(1122), 205 LP-209

• Ng GA, Mistry A, Li X, Schlindwein FS, Nicolson WB. LifeMap: towards the development of a new technology in sudden cardiac death risk stratification for clinical use. Europace. 2018;20(FI2):f162-f70.

• Almeida TP, Schlindwein FS, Salinet J, Li X, Chu GS, Tuan JH, et al. Characterization of human persistent atrial fibrillation electrograms using recurrence quantification analysis. Chaos. 2018;28(8).

• Almeida TP, Chu GS, Li X, Dastagir N, Tuan JH, Stafford PJ, Schlindwein FS, Ng GA. Atrial electrogram fractionation distribution before and after pulmonary vein isolation in human persistent atrial fibrillation - a retrospective multivariate statistical analysis. Front Physiol 8:589:1-12 doi: 10.3389/fphys.2017.00589

• Almeida TP, Chu GS, Bell MJ, Li X, Salinet JL, Dastagir N, Tuan JH, Stafford PJ, André Ng G, Schlindwein FS. The temporal behavior and consistency of bipolar atrial electrograms in human persistent atrial fibrillation. Med Biol Eng Comput. 2017.

• Salinet JL, Schindwein FS, Stafford PJ,Almeida TP, Li X, Vanheusden FJ, et al. Propagation of Meandering Rotors Surrounded by High Dominant Frequency Areas in Persistent Atrial Fibrillation.Heart Rhythm. 2017

• Li X, Salinet JL, Almeida TP, Vanheusden FJ, Chu GS, Ng GA, et al.An interactive platform to guide catheter ablation in human persistent atrial fibrillation using dominant frequency, organization and phase mapping. Computer Methods and Programs in Biomedicine. 2017;141:83-92.

• Almeida TP, Chu GS, Salinet JL, Vanheusden FJ, Li X, Tuan JH, et al. Minimizing discordances in automated classification of fractionated electrograms in human persistent atrial fibrillation. Med Biol Eng Comput. 2016;54(11):1695-706.

I am looking for talented self-motivated PhD students and researchers to work in the field of intelligent biomedical signal processing in complex cardiac arrhythmias. If you're interested feel free to contact me.

Supervision

PhDs:

Mohamed Rumi Ismail (PT) - 2021 - 

Noor N Qaqos 2022 - 

Ekenedirichukwu Obianom 2022

Shamsu Abdullahi 2023-

Fan Feng 2023-

PDRAs:

MScs (ENG):

Last Name First Name

Venkatachalam Arun Prasanth

Kancharla Gopala Krishna

Takalkar Saili Sunil

Shaik Farooq

Suresh Parvathy

 Thirumala   Udayasree 

iMScs (Meidcal):

Zobia Wadi

MDs:

Dr Sharon Man

Alumni

PDRAs:

Dr Zheheng Jiang

Dr Long Chen 

MSCs (Engineering):

Xuanlin Chen - 2020 - Distinction & best student award

Snehal Sanjay Shevate - 2020

BSCs (Medical): LUMRS Link projects

Jason R Armstrong - started 2021

Marcus O Panchal - started 2021

Ibrahim A Nasser - started 2021

Jakevir S Shoker - started 2021

Visiting students:

Jack Hall - started 2021

Teaching

Current 

EG1006 - Engineering Design and Experimentation – Academic Lead

EG7020 - MSc Individual Project

BS3X00 - 3rd year projects (School of Biological Sciences)

EG3005 - Individual Project - 3rd year Engineering projects

EG1201 Electrical & Electronic Engineering (Internal Assessor)

EG2321 Computational Engineering Methods - Module Convenor

iMSc Medical Research (Intercalated)

Previous

EG2004 - Engineering Experimentation and Analysis – Academic Lead

CTGU04 Communications

CTGU05 Automatic Control Theory

CTGU10 Signals and Systems

CTGU11 Electromagnetism

CTGU12 Electrical Engineering

Call for Papers

Submissions are welcome to our research topic in Frontiers in Physiology on Computational Methods in Cardiac rhythm disturbances.

Link:https://www.frontiersin.org/research-topics/50039/exploring-mechanisms-of-cardiac-rhythm-disturbances-using-novel-computational-methods-prediction-classification-and-therapy-volume-ii

Deadline: 01 Nov2023

• School of Engineering Plagiarism Officer

• School of Engineering Appeals panel members

• Session Chair at Computing in Cardiology 2022

• Grant reviewer of Medical Research Council (MRC)

• Grant Reviewer of Northern Ireland Chest Heart & Stroke: NICHS

• Reviewer for Expert Systems With Applications

• Reviewer Editor for Computational Physiology and Medicine, Frontiers in Physiology

• Reviewer of IEEE trans Biomedical Engineering

• Reviewer of IPEM-Translation

• Research Topic Editor of Frontiers in Physiology

• Guest Associate Editor in Cardiac Electrophysiology, Frontiers in Physiology

• Reviewer Editor for Information Theory, Frontiers in Network Physiology

• Reviewer of  MDPI journals

• Membership of European Heart Rhythm Association (EHRA)