I am a medical doctor and registrar training in public health medicine. I joined the University of Leicester in 2017 after starting the training program in the Southwest. Before that I was working in acute medicine in Belfast for three years. My role is 50:50 between academic research and public health service work. I have been a PhD student since obtaining a clinical training fellowship since April 2019 due to submit in April 2022. I live in Nottingham with my wife and young son.
My research has focussed on utilising health and questionnaire records to develop phenotypes for use in genetic studies. I have worked on phenome wide and genome wide association studies including analysis on lung disease and complex pain phenotypes.
(0) Packer R, Ben Shlomo Y, Whiting P. Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review. Cheungpasitporn W, editor. PLoS ONE. 2019 Oct 21;14(10):e0223717.
John C, Reeve NF, Free RC, Williams AT, Ntalla I, Farmaki A-E, Packer R ,et al. Cohort profile: Extended Cohort for E-health, Environment and DNA (EXCEED). International Journal of Epidemiology. 2019 Jul 31;dyz175.
Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Packer R, et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019 Mar;51(3):481-93.
Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Packer R, et al. Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. The Lancet Respiratory Medicine. 2019 Jan;7(1):20-34.
Pellacani D, Packer RJ, Frame FM, Oldridge EE, Berry PA, Labarthe M-C, et al. Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer. Mol Cancer. 2011;10(1):94.
Phenome wide association study methods and analysis.
Use of primary and secondary care records in genetic studies.
Undergraduate medical degree CPT and PaSS modules.