Dr David Lo

Dr David Lo is an Associate Professor at the University of Leicester, and an Honorary NHS Consultant at the Leicester Children’s Hospital. His clinical and academic interests are in the treatment of childhood respiratory diseases, with a focus on difficult asthma and preschool wheeze, epidemiology, and health data research. David currently holds an Advanced Research Fellowship award from the National Institute of Health and Care Research (NIHR), is the European Respiratory Society's Paediatric Epidemiology Group Secretary, an associate director with HDRUK Midlands, and an associate editor for Thorax. 

Dr David Lo's research portfolio focuses on paediatric respiratory disorders, with particular interests in:

• Childhood asthma
• Preschool wheeze
• Implementation of evidence-based care
• Epidemiology
• Routine health care data

Lo D, Quint JK. Neuropsychiatric side effects of montelukast: time to change prescribing practice? Thorax. 2024 Nov 22:thorax-2024-222643. doi: 10.1136/thorax-2024-222643. Epub ahead of print. PMID: 39578089.

Lo D, Lawson C, Gillies C, Shabnam S, Gaillard EA, Pinnock H, Quint JK. Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study. Thorax. 2024 Oct 16;79(11):1050-1059. doi: 10.1136/thorax-2023-221210. PMID: 38955499; PMCID: PMC11503080.

Hakizimana A, Lo DKH, Roland D, Rai VK, Danvers L, Rowlands R, Ahmed IA, Herzallah R, Gaillard EA.  Effectiveness of paediatric asthma hubs: a clinical pilot study. Archives of Disease in Childhood Published Online First: 29 October 2024. doi: 10.1136/archdischild-2023-326635

Pinnock H, Noble M, Lo D, McClatchey K, Marsh V, Hui CY. Personalised management and supporting individuals to live with their asthma in a primary care setting. Expert Rev Respir Med. 2023 Jul-Dec;17(7):577-596. doi: 10.1080/17476348.2023.2241357. Epub 2023 Aug 3. PMID: 37535011.

Paracha R, Lo DKH, Montgomery U, Ryan L, Varakantam V, Gaillard EA. Asthma medication adherence and exacerbations and lung function in children managed in Leicester primary care. NPJ Prim Care Respir Med. 2023 Mar 25;33(1):12. doi: 10.1038/s41533-022-00323-6. PMID: 36966170; PMCID: PMC10039953.

Lo DK, Muhlebach MS, Smyth AR. Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis. Cochrane Database Syst Rev. 2022 Dec 13;12(12):CD009650.

Devani P, Lo DKH, Gaillard EA. Practical approaches to the diagnosis of asthma in school-age children. Expert Rev Respir Med. 2022 Sep;16(9):973-981

Lo D, Beardsmore C, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA, (2021). Risk factors for asthma attacks and poor control in children: a prospective observational study in UK primary care. Arch Dis Child. 2021 May 20:archdischild-2020-320110. doi: 10.1136/archdischild-2020-320110. Epub ahead of print. PMID: 34016593.

Gaillard EA, Kuehni CE, Turner S, Goutaki M, Holden KA, de Jong CCM, Lex C, Lo DKH, Lucas JS, Midulla F, Mozun R, Piacentini G, Rigau D, Rottier B, Thomas M, Tonia T, Usemann J, Yilmaz O, Zacharasiewicz A, Moeller A, (2021). European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5-16 years. Eur Respir J. 2021 Apr 19:2004173. doi: 10.1183/13993003.04173-2020. Epub ahead of print. PMID: 33863747.

Ramphul M, Lo DKH, Gaillard EA. Precision Medicine for Paediatric Severe Asthma: Current Status and Future Direction. J Asthma Allergy. 2021 May 20;14:525-538. doi: 10.2147/JAA.S265657. Erratum in: J Asthma Allergy. 2021 Jul 02;14:785-787. PMID: 34045872; PMCID: PMC8144021.

Yang Y , Lo D, Beardsmore C, Roland D, Richardson M, Danvers L, Andrew Wilson , Gaillard E, (2021). Implementing Spirometry and Fractional Exhaled Nitric Oxide (FeNO) Testing in Childhood Asthma Management in UK primary care - an observational study to examine training and implementation cost and impact on patient's health utilization and outcome. Arch Dis Child. 2021 Jul 9:archdischild-2020-319310. doi: 10.1136/archdischild-2020-319310. Epub ahead of print. PMID: 34244168.

Lo D, Beardsmore C, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA, (2020). Spirometry and FeNO testing for asthma in children in UK primary care: a prospective observational cohort study of feasibility and acceptability. The British journal of general practice : the journal of the Royal College of General Practitioners. 70 (700).

Roland D, Teo KW, Bandi S, Lo D, Gaillard EA, (2020). COVID-19 is not a driver of clinically significant viral wheeze and asthma. Archives of disease in childhood. 106 (4).

Nenna R, Slaats M, Ersu R, Lo D, Grigg J et al. ERS International Congress, Madrid, 2019: highlights from the Paediatric Assembly. ERJ Open Res. 2020 Jul 20;6(2):00063-2020. doi: 10.1183/23120541.00063-2020. PMID: 32714968; PMCID: PMC7369464.

Lo DK, Beardsmore CS, Roland D, Richardson M, Yang Y, Danvers L, Wilson A, Gaillard EA, (2019). Lung function and asthma control in school-age children managed in UK primary care: a cohort study. Thorax. 75 (2).

Lo D, Maniyar A, Gupta S, Gaillard E, (2019). High prevalence of bronchiectasis on chest CT in a selected cohort of children with severe Asthma. BMC pulmonary medicine. 19 (1).

Andrews G, Lo DKH, Richardson M, Wilson A, Gaillard EA, (2018). Prospective observational cohort study of symptom control prediction in paediatric asthma by using the Royal College of Physicians three questions. NPJM primary care respiratory medicine. 28 (1). 

Lo D, McKimm J, Till A, (2018). Transformational leadership: is this still relevant to clinical leaders?. British journal of hospital medicine (London, England : 2005). 79 (6).

Lo D, Till A, McKimm J, (2017). What do doctors and nurses think about development of clinical leadership? British journal of hospital medicine (London, England : 2005). 78 (9).

Lo D, Bullous L, Gaillard B, Gaillard EA. Diagnosis and management of childhood asthma in primary care. Practice Nursing. 2016 Oct;27(10):488-493

David is currently supervising the following PhD students:

Aleksandra Gawlick-Lipinski - Longitudinal trends in asthma mortality and uncontrolled asthma, and predictors for asthma-related deaths in children living in England

Mariam Mourabi - Post-infectious bronchiolitis obliterans (PIBO) in Children – epidemiology, differences in care, and risk factors for poor outcomes, a mixed methods study

• Undergraduate teaching for medical students
• Postgraduate teaching for medical trainees and allied health professionals

Current positions held: 

ERS Paediatric Epidemiology Group Secretary 2024-present

HDRUK Midlands, Associate Director 2024-present

Midlands Asthma and Allergy Research Association Executive Member 2024-present

National Respiratory Audit Programme (NRAP), Research Committee Member 2024-present

Thorax, Associate Editor 2024-present

Professional organisation membership:

General Medical Council

Royal College of Paediatrics and Child Health

British Paediatric Respiratory Society

European Respiratory Society

British Thoracic Society

Medical Defence Union

British Medical Association 

Previous positions held: 

BMC Pulmonary Medicine Editorial Board 2023-2025

James Lind Alliance PSP Breathlessness 2023-2024

NHSE CYP Transformation Programme Asthma Workstream 2021-2022

ERS Paediatric Asthma Diagnosis Taskforce 2018-2021

MD (Res) - 2020

MSc (Leadership) - 2018

European Examination in Paediatric Respiratory Medicine - 2015

MRCPCH - 2010

MB ChB - 2006