I am a vascular and endovascular surgeon with an interest in clinical and translational research. My clinical focus is complex peripheral revascularisation.
I am currently based in the NIHR Leicester Biomedical Research Centre (BRC) and Department of Cardiovascular Sciences (University of Leicester) supported by an NIHR Advanced Fellowship. Prior to my current appointment I completed my higher surgical training in Birmingham (West Midlands Deanery) Leicester (East Midlands Deanery) and London (Guy's and St Thomas' NHS Foundation Trust) funded by the NIHR as a Fellow and subsequently as a Clinical Lecturer.
• Acute and Chronic Kidney Injury in Cardiovascular Surgery
Part of my clinical research has focussed on the epidemiology impact recognition and prevention of renal injury in cardiovascular patients. I have published extensively around Acute Kidney Injury (AKI) in patients having vascular procedures. This has led to the delivery of a randomised trial (HYDRA-P) and several other projects as well as a Hunterian Professorship in 2020.
• Cardiovascular Risk Reduction in Vascular Patients
I am currently leading a diverse team of experts and patient contributors (NIHR Advanced Fellowship; £1 million) to co-develop a cardiovascular risk-reduction programme specifically for patients with aneurysms. We work closely with the NHS Abdominal Aortic Aneurysm (AAA) Screening Programme (NAAASP) and other key stakeholders.
I lead four industry-funded investigator-led/sponsored clinical projects relating to the use of endovascular devices.
• Vascular and Endovascular Research Network (VERN)
I have previously led the Vascular and Endovascular Research Network (VERN) . More information: http://vascular-research.net.
(0) Selected publications - further available here: https://www.ncbi.nlm.nih.gov/pubmed/?term=saratzis+a
VERN, Saratzis A, Outcomes of Vascular and Endovascular Interventions Performed During the Coronavirus Disease 2019 (COVID-19) Pandemic. Annals of Surgery 2021; 273: 630-635.
KDIGO Conference Participants. Central and peripheral arterial diseases in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2021: S0085-2538(21)00472-5.
Sidloff DA, Saratzis A, Thompson J, Katsogridakis E, Bown MJ. Infra-Renal Aortic Diameter and Cardiovascular Risk: Making Better Use of Abdominal Aortic Aneurysm Screening Outcomes.
European Journal of Vascular and Endovascular Surgery 2021: S1078-5884(21)00270-7.
Saratzis A, Donati T, Biasi L, Diamantopoulos A, Katsanos K, Zayed H. A network meta-analysis of supervised exercise therapy, angioplasty and best medical therapy in intermittent claudication. Journal of the American College of Cardiology (JACC) Cardiovascular Interventions 2019; 24: 1125-1136.
Saratzis A, Lea T, Yap T, Batchelder A, Thomson B, Saha P, Diamantopoulos A, Saratzis N, Davies R, Zayed H. Paclitaxel and Mortality Following Peripheral Angioplasty: An Adjusted and Case Matched Multicentre Analysis. European Journal of Vascular and Endovascular Surgery 2020; 60: 220-229.
Saratzis A, Joshi S, Benson RA, Bosanquet D, Dattani N, Batchelder A, Fisher O, Ioannidou E, Bown MJ, Imray CH; VERN collaborators. Editor's Choice - Acute Kidney Injury (AKI) in Aortic Intervention: Findings From the Midlands Aortic Renal Injury (MARI) Cohort Study. European Journal of Vascular and Endovascular Surgery 2020; 59: 899-909.
Saratzis A, VERN. Observational study of the medical management of patients with peripheral artery disease. British Journal of Surgery 2019; 106:1168-1177.
Saratzis A, Chiocchia V, Jiffry A, Hassanali A, Singh S, Bown M, Mahmood A. HYDration and bicarbonate to prevent acute Renal injury after endovascular Aneurysm repair: pilot-feasibility randomized controlled study (HYDRA pilot trial). European Journal of Vascular and Endovascular Surgery 2018; 55:648-656.
Toghill BJ, Saratzis A, Freeman PJ, Sylvius N; UKAGS collaborators, Bown MJ. SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells. Clinical Epigenetics 2018; 10:29-31.
Bath M, Sidloff D, Saratzis A, UKAGS investigators. The Impact of Abdominal Aortic Aneurysm Screening on Quality of Life. British Journal of Surgery 2018; 105:203-208.
Peripheral Arterial Disease (PAD) Abdominal Aortic Aneurysm (AAA) Acute Kidney Injury (AKI) / Chronic Kidney Disease (CKD) in patients with vascular conditions. complex clinical interventions quality improvement in cardiovascular surgery.
I have been a fellow of the Higher Education Academy (FHEA) since 2016.
I regularly participate as faculty and/or organiser in national/international surgical and endovascular courses/webinars having also led several research projects investigating the role of simulation in endovascular training.
I am a faculty member of the VaLS Academy and lead the endovascular component of the course: https://www.vascularlimbsalvageacademy.com
Press and media
Abdominal aortic aneurysm Peripheral arterial disease Cardiovascular screening
07/2021- present: Member NIHR Health Technology Assessment (HTA) General Committee
10/2019 - present: Vice chair; Vascular Society of GB & Ireland Peripheral Arterial Disease Specialty Interest Group
02/2021 - present: Founding member; Research Collaboration for Peripheral Arterial Disease (RCPAD.org)
05/2020 - present: British Journal of Surgery Editor Assistant; PLOS One Associate Editor
02/2020 - present: Member; Kidney Disease Improving Global Outcomes KDIGO Vascular Conference/Committee.
01/2020-12/2020: Royal College of Surgeons of England Hunterian Professor 2020
02/2018-10/2019: Member NIHR Health Technology Assessment (HTA) Clinical Evaluation & Trials Committee
03/2018 - present: Primary Investigator (East Midlands) - UK Perioperative Medicine Clinical Trials Network
01/2018-06/2019: President - Vascular and Endovascular Research Network (VERN)
NIHR Clinical Lectureship (Vascular Surgery)
HEE Innovation Grant
European Vascular Society Prize
AMS Starter Grant
NIHR RfPB ""Female Aneurysm Screening Study"" (co-applicant)
BHF Programme Grant “Deep phenotypic characterisation of abdominal aortic aneurysm growth”
NIHR Advanced Fellowship ""Cardiovascular risk reduction In the NHS abdominal aortic aneurysm (AAA) Screening Programme - CRISP”
Abbott Medical “Treatment of common femoral artery atherosclerotic disease using the Supera stent - CONFESS”
Hunterian Professorship 2020 Royal College of Surgeons
NIHR HS&DR ""In-silico trials of targeted screening for abdominal aortic aneurysm using linked healthcare data” (co-applicant)
Circulation Foundation “The COVID-19 Vascular Service Study”
NIHR RfPB “An intervention to improve medical management of peripheral arterial disease - CHABLIS”
NIHR HTA “Diagnostic tools to establish the presence and severity of peripheral arterial disease” (co-applicant)
Shockwave Medical “Treatment of patients with peripheral artery disease using lithotripsy - SHOCC”
Abbott Medical “Fate of patients with limb ischaemia in the NHS”
·Fellow of the Royal College of Surgeons (England)
Fellow of the Higher Education Academy
PhD Vascular Surgery - multicentre project between Aristotle University (Greece) University of Birmingham (UK) and University of Leicester (UK) (2013)
Medical Degree Aristotle University (Greece) (2009)
Academic and clinical leadership training: NIHR Leadership Training (2018-19; Hult International Business School) Harvard University Surgical Leadership Programme (2019-21).