Dr Amit Mistri

• Consultant Physician in Stroke Medicine - University Hospitals of Leicester NHS Trust - Aug 2008 to date
• Deputy Clinical Director, Emergency & Specialty Medicine, UHL NHS Trust - Aug 2018 to date
• Member, UHL Thrombosis Committee - Sep 2020 to date
• Member, LLR Transferring Care Safely Board - Feb 2022 to date

Previous Roles

Chair - UHL Anti-Coagulation Committee - Sep 2016 to Aug 2020

Clinical Senate, UHL NHS Trust - Member April 2016 to Mar 2017; Vice Chair Mar 2017 to Aug 2018

Coordinator - East Midlands Stroke Group - Nov 2010 to Nov 2017

Governance Advisor for Electronic Prescribing, UHL NHS Trust - Aug 2014 to Aug 2018

Lead for Clinical Research - Stroke Medicine, UHL NHS Trust - Aug 2010 to Aug 2018

Lead for Clinical Audit - Stroke Medicine, UHL NHS Trust - Jan 2011 to Mar 2017

Lead for Clinical Governance - Stroke Medicine, UHL NHS Trust - Jan 2011 to Mar 2015

Clinical Lead – Trent Stroke Research Network (South) - August 2010 to April 2014

Lead for VLE Pilot (UHL Education Improvement Group) - Sept 2013 to Feb 2014

LeiSTAR Epidemiology Study

The LeiSTAR study has been designed to analyse routinely collected data to improve an understanding of TIA and stroke in the LLR region and to inform the strategic management strategy for these conditions.

The aims include:

1. To develop knowledge about the evolving epidemiology of stroke and TIA in Leicestershire
2. To improve understanding of the clinical characteristics of patients presenting with TIA or stroke
3. To develop clinical prediction rules that will facilitate provision of high-quality clinical care.
4. To identify avenues for improvement of management of TIA and stroke, by systematic process evaluation.

Chief Investigator: Dr Amit Mistri
Principal Investigator: Dr David Eveson (UHL NHS Trust)
Collaborators: Dr Lisa Manning, Dr Jatinder Minhas, Briana Coles, Prof Kamlesh Khunti, Prof Tom Robinson

Outputs

Papers

Mankoo AS, Minhas JS, Coles B, Hussain ST,,Khunti K, Robinson TG, Mistri AK, Eveson DJ; on behalf of the LeiSTAR Steering Committee.
Clinical relevance of orthostatic hypotension in patients with atrial fibrillation and suspected transient ischaemic attack.
High Blood Pressure and Cardiovascular Prevention 2020 27 (1): 93-101 ()

Abstracts

Manning L et al
Does symptom duration affect outcome following retinal ischaemic events?
ESOC 2022 in preparation

Mistri A et al
Burden of carotid disease underlying retinal ischaemic events
ESOC 2022 in preparation

Fazal J, Burn E, Eveson D, Mistri A.
Retrospective review of Transient Global Amnesia presentation in a TIA clinic.
UKSF 2021.

Minhas J, Coles, B, Manning L, Eveson D, Mistri AK, on behalf of the LeiSTAR Steering Committee.
Is 1-year mortality a robust metric for monitoring TIA clinic effectiveness?
UKSF 2020.

Kadicheeni M, Minhas JS, Coles B, Eveson DJ, Hussain ST, Khunti K, Robinson TG.
Mortality in a one-stop TIA clinic.
ESO-WSO Conference 2020.

Highton P, Mistri A, Ng A, Glover K, Khunti K, Seidu S. Evaluating the use of a mobile device for detection of atrial fibrillation in primary care.
British Journal of Cardiology 2021; 28(1)

Evans N, Minhas J, Mehdi Z, Mistri A. Incorporating Simulation-Based Education into Stroke Training.
Stroke 2021 52: 00-00 online

Law ZK, Dineen R, Cala L, England TJ, Mistri AK, Appleton JP, Ozturk, S, Bereczki D, Ciccone A, Bath PM, Sprigg N, on behalf of the TICH-2 investigators. Predictors and outcomes of neurological deterioration in intracerebral haemorrhage: results form the TICH-2 trial.
Translational Stroke Research 2021

Ince J, Banahan C, Venturini S, Alharbi M, Turner P, Oura M, Beach KW, Robinson TG, Mistri AK, Lecchini-Visintini A, Minhas JS, Chung EML. Acute ischemic stroke diagnosis using brain tissue pulsations.
Journal of the Neurological Sciences 2020 419: 117164

Minhas J, Coles B, Mistri AK, Eveson D, Hussain ST, Potter JF, Khunti K, Robinson TG. What is the optimal blood pressure for patients with atrial fibrillation treated with direct oral anticoagulants?
Journal of Hypertension 2020 38(9): 1820-1828

Highton P, Mistri A, Seidu S. The East Midlands Atrial Fibrillation ADVANCE Program: A service evaluation
Australian Journal of General Practice 2020 submitted

Mankoo AS, Minhas JS, Coles B, Hussain ST, Khunti K, Robinson TG, Mistri AK, Eveson DJ; on behalf of the LeiSTAR Steering Committee. Clinical relevance of orthostatic hypotension in patients with atrial fibrillation and suspected transient ischaemic attack.
High Blood Pressure and Cardiovascular Prevention 2020; 27 (1): 93-101 (alternative pdf link)

Minhas JS, Rook W, Panerai RB, Hoiland RL, Ainslie PN, Thompson JP, Mistri AK, Robinson TG. Pathophysiological and clinical considerations in the perioperative care of patients with a previous ischaemic stroke: a multidisciplinary narrative review
British Journal of Anaesthesia 2020; 124(2): 183-196

Law ZK, England TJ, Mistri AK, Woodhouse LJ, Cala L, Dineen R, Ozturk S, Beridze M, Collins R, Bath PM, Sprigg, N; on behalf of TICH-2 investigators. Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid.
European Stroke Journal 2020; 0(0): 1-7

Bhat Y, Dixit A, Mistri A, Patel B, Quoraishi SH, Uprichard J. A mixed methodology, non-interventional study to evaluate the use of direct oral anticoagulants in UK clinical practice for patients with a first stroke associated with non-valvular atrial fibrillation: study protocol.
BMC Neurology 2019; 19 (306)

Bridgwood B, Lager KE, Mistri AK, Khunti K, Wilson AD, Modi P. Interventions for improving modifiable risk factor control in the secondary prevention of stroke.
Cochrane Database of Systematic Reviews 2018, Issue 5. Art. No.: CD009103. DOI: 10.1002/14651858.CD009103.pub3.
Stroke. 2018;49:e301-e302. DOI: 10.1161/STROKEAHA.118.022213

Bose P, Tarrant C, Mistri A, Wilson A. Managing uncertainty: A qualitative study of GPs’ views on the diagnosis and immediate management of Transient Ischaemic Attack and the potential of a diagnostic tool.
Family Practice 2018; 35(6): 738-743

Hawkins L, Lincoln NB, Sprigg N, Ward NS, Mistri A, Tyrell P, Worthington E, & Drummond A. The Nottingham Fatigue After Stroke (NotFAST) Study: Results from follow-up six months after stroke.
Topics in Stroke Rehabilitation 2017 DOI: 10.1080/10749357.2017.1368912

Bose P, Wilson A, Mistri AK. The Diagnosis and Management of Transient Ischemic Attack (TIA) in Primary Care:A Systematic Review.
The Journal of Primary Health Care 2017; 9 (2): 114-130

Hawkins L, Lincoln NB, Sprigg N, Ward N, Mistri A, Tyrell P, Worthington E, Drummond A. The Nottingham Fatigue After Stroke (NotFAST) study: Factors associated with severity of fatigue in stroke patients without depression.
Clinical Rehabilitation 2017; 1-10 (DOI 10.1177/0269215517695857)

Katbamna S, Manning L, Mistri A, Johnson S, Robinson TG. Balancing Satisfaction and Stress: Carer Burden among White and British Asian Indian carers of stroke survivors.
Ethnicity & Health 2017; 22: 425-41.

Minhas JS; Syed NF; Haunton VJ; Panerai RB; Robinson TG; Mistri AK. Is dynamic cerebral autoregulation measurement using transcranial Doppler ultrasound reproducible in the presence of high concentration oxygen and carbon dioxide?
Physiol. Meas. 2016; 37: 673-82. doi:10.1088/0967-3334/37/5/673

Manning LS, Mistri AK, Rothwell PM, Potter JF, Robinson TG. Prognostic significance of blood pressure variability in acute stroke: observational analysis of the CHHIPS and COSSACS trials.
Stroke 2015; 46: 1518-1524.

Designated Medical Practitioner for Non-Medical Prescribing Course - Poonam Varu 2017-18; Habibab Hafeji 2018-19; Barry Fogarty 2018-19

PhD - Priyanka Bose - 2015 - 2020; Kate Lager PhD - 2010-13

MD - Lisa Manning 2013-16; Victoria Haunton - 2010-13

BSc - Ravinthu Thilakawardhana & Shamilah Rahman - 2013-14; Peter Connell - 2012-13; Nazia Syed & Sara Al-Ansari - 2011-12

Current

• Special Senses Block - Secondary Prevention of Stroke
• MSc Diabetes - Stroke and Diabetes Interface
• CMT Teaching - Critical Appraisal of Research
• Simulation teaching: Stroke & TIA scenarios

Past

• Vascular Biology Module - Physiological Control of BP; Blood Pressure Variability; Clinical Trial Interpretation
• People and Diseases course - Clinical Teaching
• Consultation Skills Foundation Course - Clinical Teaching
• Nervous System Module - Blood Supply to the Brain & Spinal Cord
• MSc Lectures: Biochemistry - Cerebrovascular Disease; Pain Module - Post-stroke Pain

• MB BS Christian Medical College, Vellore, India, 1995
• MRCP (UK) Royal College of Physicians, London 2001
• MD University of Leicester, Leicester 2009
• FRCP (UK) Royal College of Physicians, London 2018