Bioinformatics Research Project

Module code: MB7010

Building on the skills you have acquired in the taught modules and the steered research project, you will undertake a three month individual research project typically in research groups at the University of Leicester, though some will have external collaborations.

Examples of recent projects:

  • Comparative genomics of blood flukes
  • Identifying the transcriptional start sites of L1 retrotransposons
  • Natural variation in miRNA target sequences
  • Unravelling the significance of bidirectional promoters and the function of 'unknown' genes in genomes
  • Constructing whole genome recombination maps from Next Generation Sequencing Data
  • Trawling for satellites and transposons in living fossil genomes

Published project work by MSc Bioinformatics students

  • Saunders GI, Wasmuth JD, Beech R, Lainga R, Hunt M, Naghra H, Cotton JA, Berriman M, Britton C, Gilleard JS. (2013) 'Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes'. Int. J. Parasitol. vol.43 no.6 pp.465-475 doi:10.1016/j.ijpara.2012.12.011
  • Ray J, Dondrup M, Modha S, Steen IH, Sandaa R-A, et al. (2012) 'Finding a needle in the virus metagenome haystack – Micro-metagenome analysis captures a snapshot of the diversity of a bacteriophage armoire'. PLoS ONE 7(4): e34238. doi:10.1371/journal.pone.0034238
  • Malone J, Badarinarayan N, Ison J, Stevens R, Parkinson H. (2010) 'An ontology of bioinformatics software' Bio-Ontologies 2010, a Special Interest Group meeting at ISMB 2010. Boston, MA.
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