Bioinformatics

Module code: BS2040

‘Bioinformatics’ gives an introductory overview of the underpinning principles of molecular biology that allow the acquisition, analysis and storage of information about genomes, transcriptomes and proteomes.  This module will also illustrate how computers are used to investigate the organisation and evolution of genes and genomes. A “hands on” approach is taken by way of practical sessions held in computer laboratories. A wide range of genes and genomes are considered, with emphasis on those of model systems (yeast, Drosophila, mouse) and humans. The principles, practices and challenges of curating and making accessible biological information in databases will also be discussed. 

Topics covered

• Genome organisation and evolution 
• Gene expression and regulation 
• Scientific publications and archives
• Bioinformatics databases and information retrieval 
• Alignments and phylogenetic trees
• Structural bioinformatics and drug discovery 
• Metabolic pathways
• Bioinformatics in practice: Now and the Future