Work at LISCB

The Leicester Institute of Structural and Chemical Biology (LISCB) is a cross-disciplinary entity that brings together internationally renowned research in structural biology and chemical biology at the University of Leicester into a single world-leading unit. The Institute aims to exploit synergies in research technologies to deliver major advances in both fundamental and translational research and has the following major research strands: 

  • understanding the structure and mechanism of macromolecules and macromolecular complexes in biology
  • structure-based drug discovery and design
  • the use of single molecule techniques to understand biological processes
  • the development of chemical probes and compound libraries

Academic and Research positions at the Leicester Institute of Structural and Chemical Biology

Research associate - synthetic organic chemistry and chemical biology

  • Department of Chemistry
  • Full time, fixed term contract from 1 September 2019 to 31 August 2021
  • Salary details: Grade 7 - £34,189 to £39,609 per annum
  • Advert closes midnight on 5 July 2019

Funded by the EPSRC, the post is a collaboration between the research groups of Dr James Hodgkinson (Department of Chemistry, and Leicester Institute of Structural and Chemical Biology), Professor John Schwabe (Department of Molecular and Cell Biology, and Leicester Institute of Structural and Chemical Biology), and Professor Shaun Cowley (Department of Molecular and Cell Biology), at the University of Leicester. The project will involve the chemical synthesis and application of organic molecules as chemical probes to study Histone Deacetylase multiprotein complexes in vitro and in cell-based assays.

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Postdoctoral research associate in structural biology

  • Leicester Institute of Structural and Chemical Biology/Department of Molecular and Cell Biology
  • Full-time fixed term contract until 1 September 2022
  • Salary details: Grade 7 - £34,189 to £39,609 per annum
  • Advert closes midnight on 28 June 2019

We have an exciting opportunity for highly motivated postdoctoral candidates to lead a new project, which tackles fundamental questions in regulation of gene expression through chromatin modification. The post of Research Associate is funded by the BBSRC to investigate the role of H2B ubiquitylation in heterochromatin formation and its mechanism in the promotion of euchromatic domains. The successful candidate will join a vibrant community with strong focus on gene regulation and will be based in the research group of Dr Thomas Schalch.

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