Chronology of DNA fingerprinting at Leicester
- Professor Sir Alec Jeffreys joined the University of Leicester.
- Professor Jeffreys is joint first to describe how to detect human genetic variation at the DNA level, and first to produce a good estimate of how many sites in the genome, where genetic variation occurred.
- Professor Jeffreys is first to discover DNA fingerprinting.
- First immigration case solved by DNA fingerprinting.
- First paternity case solved by DNA fingerprinting.
- First identification of identical twins using DNA fingerprinting.
- First criminal investigation to implement DNA fingerprinting evidence.
- First detailed description of the rate of mutation in humans at the DNA level.
- First to develop sperm analysis technology.
- Identification of Josef Mengele by DNA analysis from skeletal remains.
- Professor Jeffreys contributes to work by Professor Yuri Dubrova investigating mutations caused by the Chernobyl disaster.
- First to describe in detail what a recombination ‘hotspot’ is.
- Work contributing to the ‘International HapMap Project’.
Sir Alec's present research
- Further analysis of recombination hotspots, what causes them and what affects they have on human genetic diversity?
- The implications of recombination on genes linked to diseases such as thalassaemia and diabetes.