People

Dr Justin S. Bice

Associate Professor - Programme Director MSc Medical Research (Intercalated) and Lead for Intercalation

School/Department: Leicester Medical School

Telephone: +44 (0)116 252 3095

Email: justin.bice@leicester.ac.uk

Profile

I completed my undergraduate degree at The Royal Veterinary College, University of London having spent 6 months of my final year in the department of pharmacology at Kings College London. I was awarded a Welsh School of Pharmacy PhD studentship and completed my doctoral studies in what is now The School of Pharmacy and Pharmaceutical Sciences, Cardiff University (2012). My research focused on targeting the deleterious effects of reperfusion following acute myocardial infarction, manipulating the NO-sGC-cGMP signalling cassette with novel therapeutics. During my doctoral training I spent time at Bayer Pharma AG, Wuppertal, Germany. I stayed in Cardiff, completing a British Heart Foundation post-doctoral research fellowship and subsequent university research and teaching post. I was appointed to a lectureship here at Leicester Medical School in August 2018 and was promoted to Associate Professor in January 2022.

Research

  • Myocardial Ischaemia-Reperfusion Injury
  • Vascular therapeutics
  • Prescribing education
  • Interprofessional education
  • Differential attainment

Publications

Karwi QG, Bice, JS, and Baxter GF. Pre- and postconditioning the heart with hydrogen sulfide (H2S) against ischemia/reperfusion injury in vivo: a systematic review and meta-analysis. Basic Research in Cardiology 2018; 113(1), 6.

Thomas RS, Alsaqati M, Bice JS, Hvoslef-Eide M, Good M and Kidd, EJ. Alterations in endocytic protein expression with increasing age in the transgenic APP695 V717I London mouse model of amyloid pathology - implications for Alzheimer's disease. NeuroReport 2017; 28(15): 963-968.

Bice JS, Chamberlain GR, Jones BR, Baxter GF. Nitric oxide treatments as adjuncts to reperfusion in acute myocardial infarction: a systematic review of experimental and clinical studies. Basic Research in Cardiology 2016; 111(2), 23.

Bice JS, Baxter GF. Postconditioning signaling in the heart: mechanisms and translatability. British Journal of Pharmacology. 2015; 172(8): 1933-1946.

Bice JS, Keim Y, Stasch J-P, Baxter GF. NO-independent stimulation or activation of soluble guanylyl cyclase during early reperfusion limits infarct size. Cardiovascular Research. 2014; 101: 220-228.

Bice JS, Burley DS, Baxter GF. Novel approaches and opportunities for cardioprotective signalling through 3', 5'-cyclic guanosine monophosphate manipulation. Journal of Cardiovascular Pharmacology and Therapeutics. 2014; 19 (3) 269-282.

Burley DS, Bice JS, Baxter GF. Natriuretic peptides in animal models of cardiovascular disease. Cardiovascular Endocrinology. 2014; 3(1) 19-26.

Supervision

MBChB SSC students.

MSc Medical Research (Intercalated) students.

Teaching

MBChB

  • Clinical Pharmacology, Therapeutics & Introduction to Prescribing (CPT)
  • Cardiovascular Physiology
  • Interprofessional education - Medicines Optimisation, delivered with School of Pharmacy, De Montfort University

MSc Medical Research (Intercalated)

MSc Midwifery

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