Global burden and determinants of hypoglycaemia: epidemiological analyses of the Hypoglycaemia Assessment Tool (HAT) study

Qualification: PhD

Department: Health Sciences

Application deadline: 17th December 2019

Start date: 1st February 2020



Dr. Francesco Zaccardi
Professor Kamlesh Khunti

Project Description

The Leicester Diabetes Centre, within the Health Sciences Department is offering:

Intensive glucose control results in higher rates of hypoglycaemia which negatively impacts the quality of life and prevents maintenance of a good glycaemic control. Risk factors for hypoglycaemia have been identified mainly for severe episodes in small cohorts of people with diabetes; it remains unclear, however, the impact of those factors on the absolute risk of hypoglycaemia; whether differences across geographical regions could be explained by phenotypical patients’ characteristics; or whether there are differences in the determinants of severe vs non-severe episodes of hypoglycaemia.

This PhD project will undertake a series of epidemiological analyses of the Hypoglycaemia Assessment Tool (HAT) study database, the largest global hypoglycaemia study collecting information on hypoglycaemia from 24 countries worldwide. The post holder will work to identify key patterns of hypoglycaemia and related factors, such as age, gender, glucose control, diabetes duration. The student will be embedded within a team of experts in clinical diabetes, epidemiology and statistics and receive training in a broad range of statistical methods used to investigate cross-sectional and longitudinal real-world data, as well as methods for prognostic research (development and validation of prognostic models).

The PhD project will be integrated into a vibrant postgraduate research community within the Real World Evidence Unit and the Diabetes Research Centre, University of Leicester and help advance the aims of the National Institute of Health Research Leicester Biomedical Research Centre (BRU) and East Midlands Collaboration for Leadership in Applied Health Research and Care (CLAHRC).



The studentship is funded by Novo Nordisk and offers:

3 years stipend at UKRI rates currently £15,009 per year

3 years tuition fees at UK/EU rates

Research support grant (including travel allowance of £2,500 per year for 3 years.

Entry requirements

Entry requirements

UK Bachelor Degree with at least 2:1 in a relevant subject or overseas equivalent in a relevant subject.

Evidence of English language if applicable.

Informal enquiries

Informal enquiries

Project enquiries to: 

Dr Francesco Zaccardi 
Professor Kamlesh Khunti

Application enquiries to:

How to apply

How to apply

Please us the Apply button at the bottom of the page and select January 2020 entry.

In the funding section of the application please indicate you wish to be considered for TM65001 Zaccardi_Novo Studentship 

In the proposal section please provide the name of the supervisor and project. 

  • CV
  • personal statement explaining your interest in the project and why we should consider you together with all other relevant application documents.
  • Degree Certificates and Transcripts of study already completed and if possible transcript to date of study currently being undertaken
  • Evidence of English language proficiency if applicable
  • In the reference section please enter the contact details of your referees or upload letters of reference if already available.



The project and funding are only available to UK/EU applicants