- Professor Thomas Yates
- Dr Claire Lawson
- Karen Tingay
People with underlying health conditions such as diabetes, hypertension, asthma, heart failure, chronic kidney disease, have been found to have the highest risk of developing severe COVID-19 infection resulting in hospitalisation or even mortality. Most of the research to date has focused on single chronic conditions, yet individuals often have multiple chronic conditions, known as multimorbidity. Understanding the impact of COVID-19 in those with multimorbidity has important clinical and public health implications which are not entirely captured by a focus on single conditions.
This PhD project aims to use large routinely collected data and the UK ONS Census data to investigate the initial and longer-term effects of the risk associated with multimorbidity on outcomes in patients with COVID-19 in the UK population. The specific objectives are to:
• Investigate the effects of the national lockdown on routine health care, lifestyle, mental and physical health conditions.
• Explore the direct and indirect impact of COVID-19 on mortality and life expectancy.
• To explore the effectiveness of vaccines by different pre-existing multimorbidity conditions.
The PhD will be suitable for a person with a background in Statistics and/or Epidemiology. The research programme will involve a range of data sources and methodologies, ranging from simple descriptive statistics to advanced survival modelling.
The PhD project will be integrated into a vibrant postgraduate research community within the Real World Evidence Unit and the Diabetes Research Centre, University of Leicester, and help advance the aims of the National Institute of Health Research Leicester Biomedical Research Centre (BRU) and East Midlands Applied Research Collaboration (ARC). The Centre provides a stimulating and exciting environment in which to study for a postgraduate degree.