Genetic Epidemiology

Module code: MD7448
Module coordinator: Nuala Sheehan, Louise Wain

Genetic epidemiology is an exciting and fast-moving field with many career opportunities spanning both methodological and applied research.

If you select this module you will be introduced to the basic biology and genetics, and statistical and epidemiological concepts that underpin genetic epidemiology.  

Practical sessions will give you experience of running and interpreting a genetic association analysis including multiple genetic variants. We will explore the fundamental concepts underpinning analyses of family-based data, recurrence risk ratios, heritability and variance components analysis.

After studying the use of genetic data in causal inference through 'Mendelian Randomisation', you will put this theory into practice with a computer-based exercise. You will explore statistical issues of current relevance to the field through practical exercises and discuss their application to current genetic epidemiological study design. We will also look at how relatedness between individuals is taken into account in association studies.

Learning

  • 18 one-hour lectures
  • 16 one-hour practical sessions

Assessment

  • Coursework 1 (50%)
  • Coursework 2 (50%)