Medical Genetics

This module may only be taken by Medical Genetics students.

Module code: MB3050

Module co-ordinators: Dr Christopher Talbot and Dr Ed Hollox

Module Aims

The aim of the module is to give students an appreciation of the application of genetics to a broad range of areas of modern medicine.

Learning Outcomes

By the end of the module students should be able to:

  • Assess how genetics has impacted upon the practice of medicine
  • Outline the problems and advances in using genetics to understand complex diseases
  • Illustrate the ways in which genetic knowledge is impacting on cancer therapeutics
  • Demonstrate a knowledge of the contribution of genetics to the study of brain diseases, heart disease and cancer
  • Research and integrate information from a range of sources in order to give a critical appraisal of a chosen specialist area
  • Appraise a current research paper and give an oral presentation on it

Module Description

The lecture programme will consist of 24 lectures covering the following topics:

  • Cancer Genetics
  • Cardiovascular Genetics
  • Neurogenetics
  • Genomic variation and disease
  • Genetic epidemiology
  • Pharmacogenetics


The tutorial programme will support the lectures and will take three forms:

  1. Discussions of clinical case studies and assessment of risk in medical genetics
  2. Research article presentations
  3. An exam clinic


  • Examination: 70%
  • Continuous assessment: 30%, consisting of an oral presentation (10%) and an essay (20%)

Recommended Books

Strachan, T. and Read, A.P. (2011). Human Molecular Genetics, (4th edition), published by Garland Science. ISBN 978-0815341499, £40.00.

Lists of original research articles and reviews will be given during the module.