Biological Chemistry

Module code: CH7011

Module co-ordinator: Dr Bernard Rawlings

Topics covered

  • Principal types of enzymic catalysis, including methods for probing the structure and function of biomacromolecules.
  • Preparative biological chemistry (synthesis) relevant to the pharmaceutical industry and drug-discovery programmes.
  • Combinatorial syntheses and the contribution of this field to the identification of lead compounds.
  • Principal techniques for biological assays, including methods for high throughput screening.
  • How computational methods contribute to inhibitor design.
  • Importance of genomics and proteomics in the field of drug discovery.
  • Industrial applications of biocatalysis: synthesis, bioremediation, biological washing powders etc.

Learning

  • 45 one-hour lectures
  • 4 one-hour seminars

Assessment

  • Exam, 3 hours (70%)
  • Individual and group-directed learning assessments (30%)
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