Module code: CH7011
Module co-ordinator: Dr Bernard Rawlings
- Principal types of enzymic catalysis, including methods for probing the structure and function of biomacromolecules.
- Preparative biological chemistry (synthesis) relevant to the pharmaceutical industry and drug-discovery programmes.
- Combinatorial syntheses and the contribution of this field to the identification of lead compounds.
- Principal techniques for biological assays, including methods for high throughput screening.
- How computational methods contribute to inhibitor design.
- Importance of genomics and proteomics in the field of drug discovery.
- Industrial applications of biocatalysis: synthesis, bioremediation, biological washing powders etc.
- 45 one-hour lectures
- 4 one-hour seminars
- Exam, 3 hours (70%)
- Individual and group-directed learning assessments (30%)