Biochemistry 3: Cellular Regulation of Energy and Metabolism

Module code: BS2093

Module co-ordinators: Ralf Schmid

In this module you will study how cells generate and use energy.  After learning the general aspects of enzyme kinetics and regulation you will study the pathways involved in the catabolism of dietary carbohydrates and lipids. Key aspects we will explore include how metabolism is regulated as a consequence of metabolic demand and how defects in metabolic control mechanisms can lead to disease. You will also learn about the molecular mechanisms involved in energy transduction as shown by proteins involved in movement, electron transport and ATP synthesis. Finally we will look at the special metabolic requirements of a cancer cell and how these determine tumour progression.

Topics covered

  • Selected aspects of carbohydrate metabolism
  • Aspects of lipid metabolism
  • Oxidative phosphorylation and ATP synthesis
  • Cancer metabolism
  • Properties of enzymes, enzyme kinetics and regulation
  • Energy use in motility and transport


  • 27 one-hour lectures
  • 12 hours of practicals
  • 1 two-hour tutorial


  • Exam, 3 hours (70%)
  • Practical write-up (10%)
  • Tutorial (20%)